[Term]
id: PR:000004894
name: complement C1s subcomponent
def: "A protein that is a translation product of the human C1S gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "C1S" EXACT PRO-short-label [PRO:DNx]
synonym: "C1 esterase" RELATED []
synonym: "complement component 1 subcomponent s" EXACT []
xref: IUPHARobj:2335
is_a: PR:000000001 ! protein

[Term]
id: PR:P09871
name: complement C1s subcomponent (human)
def: "A complement C1s subcomponent that is encoded in the genome of human." [PRO:DNx, UniProtKB:P09871]
comment: Category=organism-gene.
synonym: "C1S" RELATED Gene-based [UniProtKB:P09871]
synonym: "hC1S" EXACT PRO-short-label [PRO:DNx]
synonym: "C1 esterase (human)" EXACT [UniProtKB:P09871]
synonym: "complement component 1 subcomponent s (human)" EXACT [UniProtKB:P09871]
xref: UniProtKB:P09871
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000004894 ! complement C1s subcomponent
relationship: has_gene_template HGNC:1247 ! C1S (human)

[Term]
id: PR:000046528
name: complement C1s subcomponent, signal peptide removed form (human)
def: "A complement C1s subcomponent (human) that has had the signal peptide removed. UniProtKB:P09871, 16-688." [PRO:DNx, Reactome:R-HSA-173557]
comment: Category=organism-modification.
synonym: "hC1S/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000027586" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P09871, 16-688" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-173557 "PR:000046528 located_in GO:0005576"
intersection_of: PR:P09871 ! complement C1s subcomponent (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000054674
name: complement C1s subcomponent N-glycosylated 1 (human)
def: "A complement C1s subcomponent (human) that has been N-glycosylated at the residue equivalent to Asn-174 of the amino acid sequence represented by UniProtKB:P09871-1, in which the glycan composition is represented by GlyTouCan:G00912UN. Example: UniProtKB:P09871-1, Asn-174, MOD:00160~GNO:G00912UN." [GlyGen:P09871-1, PMID:29671580, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hC1S/NGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P09871-1, Asn-174, MOD:00160~GNO:G00912UN" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P09871 ! complement C1s subcomponent (human)
relationship: has_part GNO:G00912UN ! G00912UN
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000019172
name: complement C1s subcomponent proteolytic cleavage product
def: "A complement C1s subcomponent that has been processed by proteolytic cleavage." [PRO:DNx]
comment: Category=modification.
synonym: "C1S/ClvPrd" EXACT PRO-short-label [PRO:DNx]
intersection_of: output_of GO:0016485 ! protein processing
intersection_of: PR:000004894 ! complement C1s subcomponent

[Term]
id: PR:000019171
name: complement C1s subcomponent, signal peptide removed form
def: "A complement C1s subcomponent that has had the signal peptide removed." [PRO:DNx]
comment: Category=modification.
synonym: "C1S/SigPep-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000004894 ! complement C1s subcomponent
intersection_of: lacks_part SO:0000418 ! signal_peptide

[Term]
id: PR:Q6P6T1
name: complement C1s subcomponent (rat)
def: "A complement C1s subcomponent that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-gene.
synonym: "C1s" RELATED Gene-based [UniProtKB:Q6P6T1]
synonym: "rC1S" EXACT PRO-short-label [PRO:DNx]
synonym: "r-gsp" RELATED Gene-based [UniProtKB:Q6P6T1]
synonym: "C1 esterase (rat)" EXACT [UniProtKB:Q6P6T1]
synonym: "complement component 1 subcomponent s (rat)" EXACT [UniProtKB:Q6P6T1]
xref: UniProtKB:Q6P6T1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000004894 ! complement C1s subcomponent
relationship: has_gene_template RGD:619983 ! C1s (rat)