[Term] id: PR:000035362 name: mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 1 (human) def: "A mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 1 in human. Example: UniProtKB:O60566-1, Thr-620, MOD:00047." [PMID:17785528, PRO:KER] comment: Category=organism-modification. Kinase=("CDK1"; PR:000003271). synonym: "hBUB1B/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "hBUBR1 phosphorylated" RELATED [] synonym: "BUBR1 phosphorylated (human)" RELATED [] synonym: "UniProtKB:O60566-1, Thr-620, MOD:00047" NARROW PRO-proteoform-std [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000035361 ! mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 1 relationship: has_part MOD:00047 ! O-phospho-L-threonine [Term] id: PR:P41695 name: checkpoint serine/threonine-protein kinase BUB1 (yeast) def: "A mitotic checkpoint serine/threonine-protein kinase BUB1 beta that is encoded in the genome of yeast." [OMA:P41695, PRO:CNA, PRO:DAN] comment: Category=organism-gene. synonym: "BUB1" RELATED Gene-based [UniProtKB:P41695] synonym: "G7542" RELATED Gene-based [UniProtKB:P41695] synonym: "yBUB1B" EXACT PRO-short-label [PRO:DNx] synonym: "YGR188C" RELATED Gene-based [UniProtKB:P41695] xref: UniProtKB:P41695 intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C intersection_of: PR:000004855 ! mitotic checkpoint serine/threonine-protein kinase BUB1 beta relationship: has_gene_template SGD:S000003420 ! BUB1 (yeast) [Term] id: PR:Q800D4 name: mitotic checkpoint serine/threonine-protein kinase BUB1 beta (chicken) def: "A mitotic checkpoint serine/threonine-protein kinase BUB1 beta that is encoded in the genome of chicken." [PMID:17276342, PRO:KER] comment: Category=organism-gene. synonym: "BubR1" RELATED Gene-based [UniProtKB:Q800D4] synonym: "chick-BUB1B" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q800D4 intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus intersection_of: PR:000004855 ! mitotic checkpoint serine/threonine-protein kinase BUB1 beta relationship: has_gene_template CGNC:3590 ! BUB1B (chicken) [Term] id: PR:000004855 name: mitotic checkpoint serine/threonine-protein kinase BUB1 beta def: "A BUB1/BUB1B protein that is a translation product of the human BUB1B gene or a 1:1 ortholog thereof." [PMID:22698286, PRO:CNA] comment: Category=gene. synonym: "SSK1" RELATED Gene-based [] synonym: "BUB1B" EXACT PRO-short-label [PRO:DNx] synonym: "BUBR1" RELATED Gene-based [] synonym: "BubR1" EXACT [] synonym: "MAD3L" RELATED Gene-based [] synonym: "protein SSK1" EXACT [] synonym: "mitotic checkpoint kinase MAD3L" EXACT [] synonym: "MAD3/BUB1-related protein kinase" EXACT [] xref: IUPHARobj:1950 is_a: PR:000035665 ! BUB1/BUB1B protein [Term] id: PR:Q8JGT8 name: mitotic checkpoint serine/threonine-protein kinase BUB1 beta (frog) def: "A mitotic checkpoint serine/threonine-protein kinase BUB1 beta that is encoded in the genome of frog." [PMID:12163471, PMID:15241477, PMID:16950116, PRO:KER] comment: Category=organism-gene. synonym: "xBUBR1" EXACT [] synonym: "frog-BUB1B" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q8JGT8 intersection_of: only_in_taxon NCBITaxon:8355 ! Xenopus laevis intersection_of: PR:000004855 ! mitotic checkpoint serine/threonine-protein kinase BUB1 beta relationship: has_gene_template NCBIGene:378923 ! bub1b (frog) [Term] id: PR:000035361 name: mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 1 def: "A mitotic checkpoint serine/threonine-protein kinase BUB1 beta that has been phosphorylated at the position equivalent to Thr-620 of the amino acid sequence represented by UniProtKB:O60566-1. Example: UniProtKB:O60566-1, Thr-620, MOD:00047." [PMID:17785528, PRO:KER] comment: Category=modification. synonym: "BUB1B/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "BUBR1 phosphorylated" RELATED [] is_a: PR:000004855 ! mitotic checkpoint serine/threonine-protein kinase BUB1 beta relationship: has_part MOD:00047 ! O-phospho-L-threonine [Term] id: PR:Q9Z1S0 name: mitotic checkpoint serine/threonine-protein kinase BUB1 beta (mouse) def: "A mitotic checkpoint serine/threonine-protein kinase BUB1 beta that is encoded in the genome of mouse." [OMA:Q9Z1S0, PRO:DNx] comment: Category=organism-gene. synonym: "Bub1b" RELATED Gene-based [UniProtKB:Q9Z1S0] synonym: "Mad3l" RELATED Gene-based [UniProtKB:Q9Z1S0] synonym: "mBUB1B" EXACT PRO-short-label [PRO:DNx] synonym: "BubR1 (mouse)" EXACT [UniProtKB:Q9Z1S0] synonym: "mitotic checkpoint kinase MAD3L (mouse)" EXACT [UniProtKB:Q9Z1S0] synonym: "MAD3/BUB1-related protein kinase (mouse)" EXACT [UniProtKB:Q9Z1S0] xref: UniProtKB:Q9Z1S0 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000004855 ! mitotic checkpoint serine/threonine-protein kinase BUB1 beta relationship: has_gene_template MGI:1333889 ! Bub1b (mouse) [Term] id: PR:000028798 name: mitotic checkpoint serine/threonine-protein kinase BUB1 beta isoform 1 acetylated 1 (human) def: "A mitotic checkpoint serine/threonine-protein kinase BUB1 beta isoform 1 acetylated 1 in human. Acetylation of this site inhibits ubiquitin mediated proteolysis and modulates timing for entry into anaphase. UniProtKB:O60566-1, Lys-250, MOD:00064." [PMID:19407811, PRO:PD] comment: Category=organism-modification. Acetylase=("KAT2B"; PR:000012332). synonym: "hBUB1B/iso:1/Ac:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:O60566-1, Lys-250, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000028797 ! mitotic checkpoint serine/threonine-protein kinase BUB1 beta isoform 1 acetylated 1 relationship: has_part MOD:00064 ! N6-acetyl-L-lysine [Term] id: PR:000035426 name: mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 1 (frog) def: "A mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 1 in frog. UniProtKB:Q8JGT8, Thr-605, MOD:00047." [PMID:17998400, PRO:KER] comment: Category=organism-modification. Kinase=("Cdk1:Cyclin B"; PR:000029190). synonym: "frog-BUB1B/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "xBUBR1 phosphorylated" RELATED [] synonym: "BUBR1 phosphorylated (frog)" RELATED [] synonym: "UniProtKB:Q8JGT8, Thr-605, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:8355 ! Xenopus laevis intersection_of: PR:000035361 ! mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 1 relationship: has_part MOD:00047 ! O-phospho-L-threonine [Term] id: PR:000035427 name: mitotic checkpoint serine/threonine-protein kinase BUB1 beta CDK1- and PLK1-phosphorylated form def: "A mitotic checkpoint serine/threonine-protein kinase BUB1 beta that has been phosphorylated at one or more CDK1 and PLK1 consensus sites. The phosphorylation at CDK1 site(s) is necessary for the phosphorylation at the PLK1 site(s) to occur. Example: UniProtKB:O60566, Thr-620, MOD:00047|(Ser-676, MOD:00046 and/or Thr-680, MOD:00047)|(Thr-792, MOD:00047 and/or Thr-1008, MOD:00047)." [PMID:10593653, PMID:11030144, PMID:11792804, PMID:17276342, PMID:17376779, PMID:17785528, PMID:18440313, PRO:KER] comment: Category=modification. synonym: "BUB1B/Phos:CDK1+PLK1" EXACT PRO-short-label [PRO:DAN] synonym: "BUBR1 phosphorylated" RELATED [] is_a: PR:000004855 ! mitotic checkpoint serine/threonine-protein kinase BUB1 beta relationship: has_part MOD:00047 ! O-phospho-L-threonine relationship: has_part MOD:00696 ! phosphorylated residue [Term] id: PR:000035425 name: mitotic checkpoint serine/threonine-protein kinase BUB1 beta unphosphorylated form (frog) def: "A mitotic checkpoint serine/threonine-protein kinase BUB1 beta unphosphorylated form in frog." [PRO:CNA] comment: Category=organism-modification. synonym: "frog-BUB1B/PhosRes-" EXACT PRO-short-label [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:8355 ! Xenopus laevis intersection_of: PR:000035372 ! mitotic checkpoint serine/threonine-protein kinase BUB1 beta unphosphorylated form [Term] id: PR:000035435 name: mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 4 (human) def: "A mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 4 in human. This phosphorylated form is observed in prophase, prometaphase, metaphase, anaphase, spindle depolymerization (nocodazole). This form is not observed when there is a lack of kinetochore tension (taxol). Ser-435, Ser-574 and Ser-720 could also be phosphorylated. Example: UniProtKB:O60566-1, Ser-543/Ser-670/Ser-1043, MOD:00046." [PMID:19015317, PMID:20016069, PRO:KER] comment: Category=organism-modification. Kinase=("CDK1"; PR:000003271). synonym: "hBUB1B/Phos:4" EXACT PRO-short-label [PRO:DNx] synonym: "hBUBR1 phosphorylated" RELATED [] synonym: "BUBR1 phosphorylated (human)" RELATED [] synonym: "UniProtKB:O60566-1, Ser-543/Ser-670/Ser-1043, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000035434 ! mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 4 relationship: has_part MOD:00046 ! O-phospho-L-serine [Term] id: PR:000035428 name: mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 2 (human) def: "A mitotic checkpoint serine/threonine-protein kinase BUB1 beta CDK1- and PLK1-phosphorylated form in human that has had Thr-620 phosphorylated by CDK1, and Ser-676 and/or Thr-680 phosphorylated by PLK1. Additionally, Thr-792 and/or Thr-1008 may be phosphorylated based on in vitro experiments. This phosphorylated form is observed during pro metaphase, spindle depolymerization (nocodazole), and lack of kinetochore tension (taxol). Example: UniProtKB:O60566, Thr-620, MOD:00047|(Ser-676, MOD:00046 and/or Thr-680, MOD:00047)|(Thr-792, MOD:00047 and/or Thr-1008, MOD:00047)." [PMID:10593653, PMID:11030144, PMID:11792804, PMID:17276342, PMID:17376779, PMID:17785528, PMID:18440313, PMID:23079597, PRO:KER] comment: Category=organism-modification. Kinase=("CDK1"; PR:000003271). Kinase=("PLK1"; PR:P53350). synonym: "hBUB1B/Phos:2" EXACT PRO-short-label [PRO:DNx] synonym: "hBUBR1 phosphorylated" RELATED [] synonym: "BUBR1 phosphorylated (human)" RELATED [] synonym: "UniProtKB:O60566, Thr-620, MOD:00047|(Ser-676, MOD:00046 and/or Thr-680, MOD:00047)|(Thr-792, MOD:00047 and/or Thr-1008, MOD:00047)" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:000035427 ! mitotic checkpoint serine/threonine-protein kinase BUB1 beta CDK1- and PLK1-phosphorylated form relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: has_part MOD:00047 ! O-phospho-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000035373 name: mitotic checkpoint serine/threonine-protein kinase BUB1 beta unphosphorylated form (human) def: "A mitotic checkpoint serine/threonine-protein kinase BUB1 beta unphosphorylated form in human." [PRO:CNA] comment: Category=organism-modification. synonym: "hBUB1B/PhosRes-" EXACT PRO-short-label [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000035372 ! mitotic checkpoint serine/threonine-protein kinase BUB1 beta unphosphorylated form [Term] id: PR:000028797 name: mitotic checkpoint serine/threonine-protein kinase BUB1 beta isoform 1 acetylated 1 def: "A mitotic checkpoint serine/threonine-protein kinase BUB1 beta isoform 1 that has been acetylated on the Lys residue within the conserved sequence RVGGALKA. Example: UniProtKB:O60566-1, Lys-250, MOD:00064." [PMID:19407811, PRO:PD] comment: Category=modification. synonym: "BUB1B/iso:1/Ac:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000028795 ! mitotic checkpoint serine/threonine-protein kinase BUB1 beta isoform 1 relationship: has_part MOD:00064 ! N6-acetyl-L-lysine [Term] id: PR:000035431 name: mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 3 def: "A mitotic checkpoint serine/threonine-protein kinase BUB1 beta that has been phosphorylated on a residue equivalent to Thr-608 of the amino acid sequence represented by UniProtKB:O60566-1. Example: UniProtKB:O60566-1, Thr-608, MOD:00047." [PMID:10593653, PMID:10749118, PMID:22801780, PRO:KER] comment: Category=modification. There is some controversy in the literature on whether BUB1B has kinase activity or is a pseudokinase. synonym: "BUB1B/Phos:3" EXACT PRO-short-label [PRO:DNx] synonym: "BUBR1 phosphorylated" RELATED [] is_a: PR:000004855 ! mitotic checkpoint serine/threonine-protein kinase BUB1 beta relationship: has_part MOD:00047 ! O-phospho-L-threonine [Term] id: PR:000035430 name: mitotic checkpoint serine/threonine-protein kinase BUB1 beta CDK1- and PLK1-phosphorylated form (frog) def: "A mitotic checkpoint serine/threonine-protein kinase BUB1 beta CDK1- and PLK1-phosphorylated form in frog. This phosphorylation form is observed during mitosis and in conditions of spindle depolymerization (nocodazole). MAD1 is needed for this phosphorylation. UniProtKB:Q8JGT8, Thr-605, MOD:00047|MOD:00696." [PMID:12163471, PMID:17998400, PRO:KER] comment: Category=organism-modification. Kinase=("PLK1"; PR:P70032). Kinase=("cyclin B:Cdk1 complex"; PR:000029190). synonym: "frog-BUB1B/Phos:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q8JGT8, Thr-605, MOD:00047|MOD:00696" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:000035427 ! mitotic checkpoint serine/threonine-protein kinase BUB1 beta CDK1- and PLK1-phosphorylated form relationship: has_part MOD:00047 ! O-phospho-L-threonine relationship: has_part MOD:00696 ! phosphorylated residue relationship: only_in_taxon NCBITaxon:8355 ! Xenopus laevis [Term] id: PR:000035433 name: mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 3 (frog) def: "A mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 3 in frog. UniProtKB:Q8JGT8, Thr-593, MOD:00047." [PMID:22801780, PRO:KER] comment: Category=organism-modification. One of the articles cited mentions BUB1B (PR:Q8JGT8) as the kinase when bound to CENPE (PR:O42263). synonym: "frog-BUB1B/Phos:3" EXACT PRO-short-label [PRO:DNx] synonym: "xBUBR1 phosphorylated" RELATED [] synonym: "BUBR1 phosphorylated (frog)" RELATED [] synonym: "UniProtKB:Q8JGT8, Thr-593, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:8355 ! Xenopus laevis intersection_of: PR:000035431 ! mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 3 relationship: has_part MOD:00047 ! O-phospho-L-threonine [Term] id: PR:000035432 name: mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 3 (human) def: "A mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 3 in human. This phosphorylated form is observed in prometaphase and in conditions of spindle depolymerization (nocodazole). Example: UniProtKB:O60566-1, Thr-608, MOD:00047." [PMID:10593653, PMID:10749118, PMID:22801780, PRO:KER] comment: Category=organism-modification. One of the articles cited mentions BUB1B (PR:O60566) as the kinase when bound to CENPE (PR:Q02224). synonym: "hBUB1B/Phos:3" EXACT PRO-short-label [PRO:DNx] synonym: "hBUBR1 phosphorylated" RELATED [] synonym: "BUBR1 phosphorylated (human)" RELATED [] synonym: "UniProtKB:O60566-1, Thr-608, MOD:00047" NARROW PRO-proteoform-std [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000035431 ! mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 3 relationship: has_part MOD:00047 ! O-phospho-L-threonine [Term] id: PR:000035372 name: mitotic checkpoint serine/threonine-protein kinase BUB1 beta unphosphorylated form def: "A mitotic checkpoint serine/threonine-protein kinase BUB1 beta that lacks phosphorylated residues." [PRO:CNA] comment: Category=modification. synonym: "BUB1B/PhosRes-" EXACT PRO-short-label [PRO:DNx] synonym: "BUBR1 unphosphorylated" RELATED [] intersection_of: lacks_part MOD:00696 ! phosphorylated residue intersection_of: PR:000004855 ! mitotic checkpoint serine/threonine-protein kinase BUB1 beta [Term] id: PR:000035434 name: mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 4 def: "A mitotic checkpoint serine/threonine-protein kinase BUB1 beta that has been phosphorylated on residues equivalent to Ser-543, Ser-670, and Ser-1043 of the amino acid sequence represented by UniProtKB:O60566-1. Additional Ser residues could be phosphorylated. Example: UniProtKB:O60566-1, Ser-543/Ser-670/Ser-1043, MOD:00046." [PMID:19015317, PMID:20016069, PRO:KER] comment: Category=modification. synonym: "BUB1B/Phos:4" EXACT PRO-short-label [PRO:DNx] synonym: "BUBR1 phosphorylated" RELATED [] is_a: PR:000004855 ! mitotic checkpoint serine/threonine-protein kinase BUB1 beta relationship: has_part MOD:00046 ! O-phospho-L-serine [Term] id: PR:O60566 name: mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) def: "A mitotic checkpoint serine/threonine-protein kinase BUB1 beta that is encoded in the genome of human." [PRO:DNx, UniProtKB:O60566] comment: Category=organism-gene. synonym: "SSK1" RELATED Gene-based [UniProtKB:O60566] synonym: "BUB1B" RELATED Gene-based [UniProtKB:O60566] synonym: "BUBR1" RELATED Gene-based [UniProtKB:O60566] synonym: "MAD3L" RELATED Gene-based [UniProtKB:O60566] synonym: "hBUB1B" EXACT PRO-short-label [PRO:DNx] synonym: "hBUBR1" EXACT [UniProtKB:O60566] synonym: "protein SSK1 (human)" EXACT [UniProtKB:O60566] synonym: "mitotic checkpoint kinase MAD3L (human)" EXACT [UniProtKB:O60566] synonym: "MAD3/BUB1-related protein kinase (human)" EXACT [UniProtKB:O60566] xref: DTO:03100051 xref: UniProtKB:O60566 xref: Reactome:R-HSA-141436 "PR:O60566 located_in GO:0005829" intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000004855 ! mitotic checkpoint serine/threonine-protein kinase BUB1 beta relationship: has_gene_template HGNC:1149 ! BUB1B (human) [Term] id: PR:000028795 name: mitotic checkpoint serine/threonine-protein kinase BUB1 beta isoform 1 def: "A mitotic checkpoint serine/threonine-protein kinase BUB1 beta that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O60566-1 or a 1:1 ortholog thereof." [PMID:19407811, PRO:PD] comment: Category=sequence. synonym: "BUB1B/iso:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000004855 ! mitotic checkpoint serine/threonine-protein kinase BUB1 beta [Term] id: PR:O60566-2 name: mitotic checkpoint serine/threonine-protein kinase BUB1 beta isoform h2 (human) def: "A mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O60566-2." [PRO:DNx, UniProtKB:O60566] comment: Category=organism-sequence. synonym: "hBUB1B/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:O60566-2 is_a: PR:O60566 ! mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:O60566-3 name: mitotic checkpoint serine/threonine-protein kinase BUB1 beta isoform h3 (human) def: "A mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O60566-3." [PRO:DNx, UniProtKB:O60566] comment: Category=organism-sequence. synonym: "hBUB1B/iso:h3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:O60566-3 is_a: PR:O60566 ! mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:O60566-1 name: mitotic checkpoint serine/threonine-protein kinase BUB1 beta isoform 1 (human) def: "A mitotic checkpoint serine/threonine-protein kinase BUB1 beta isoform 1 that is encoded in the genome of human." [PRO:PD] comment: Category=organism-sequence. synonym: "hBUB1B/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:O60566-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000028795 ! mitotic checkpoint serine/threonine-protein kinase BUB1 beta isoform 1