[Term]
id: PR:000004637
name: barrier-to-autointegration factor
def: "A protein that is a translation product of the human BANF1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "BAF" RELATED Gene-based []
synonym: "BANF1" EXACT PRO-short-label [PRO:DNx]
synonym: "BCRG1" RELATED Gene-based []
synonym: "Bcrp1" RELATED Gene-based []
synonym: "L2bp1" RELATED Gene-based []
synonym: "LAP2-binding protein 1" EXACT []
synonym: "breakpoint cluster region protein 1" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000046460
name: barrier-to-autointegration factor phosphorylated 2 (human)
def: "A barrier-to-autointegration factor (human) that has been post-translationally modified to include phosphothreonine at positions 2 and 3, and phosphoserine at position 4 of the amino acid sequence represented by UniProtKB:O75531. UniProtKB:O75531, Thr-2/Thr-3, MOD:00047|Ser-4, MOD:00046." [PRO:DNx, Reactome:R-HSA-2993896, Reactome:R-HSA-2995375]
comment: Category=organism-modification.
synonym: "hBANF1/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O75531, Thr-2/Thr-3, MOD:00047|Ser-4, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2993896 "PR:000046460 located_in GO:0005654"
xref: Reactome:R-HSA-2995375 "PR:000046460 located_in GO:0005829"
is_a: PR:O75531 ! barrier-to-autointegration factor (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000036220
name: barrier-to-autointegration factor acetylated 1 (human)
def: "A barrier-to-autointegration factor that is N-terminal Met acetylated in human. UniProtKB:O75531, Met-1, MOD:00058." [TDR:1150]
comment: Category=organism-modification. Note: Top down proteomics. Evidence=(ECO:0000006).
synonym: "hBANF1/Ac:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O75531, Met-1, MOD:00058" EXACT PRO-proteoform-std [PRO:DNx]
xref: TDR:1150
is_a: PR:000004637 ! barrier-to-autointegration factor
relationship: has_part MOD:00058 ! N-acetyl-L-methionine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O75531
name: barrier-to-autointegration factor (human)
def: "A barrier-to-autointegration factor that is encoded in the genome of human." [PRO:DNx, UniProtKB:O75531]
comment: Category=organism-gene.
synonym: "BAF" RELATED Gene-based [UniProtKB:O75531]
synonym: "BANF1" RELATED Gene-based [UniProtKB:O75531]
synonym: "BCRG1" RELATED Gene-based [UniProtKB:O75531]
synonym: "hBANF1" EXACT PRO-short-label [PRO:DNx]
synonym: "breakpoint cluster region protein 1 (human)" EXACT [UniProtKB:O75531]
xref: Reactome:R-HSA-175030 "PR:O75531 located_in GO:0005654"
xref: Reactome:R-HSA-175371 "PR:O75531 located_in GO:0005829"
xref: UniProtKB:O75531
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000004637 ! barrier-to-autointegration factor
relationship: has_gene_template HGNC:17397 ! BANF1 (human)

[Term]
id: PR:000045608
name: barrier-to-autointegration factor phosphorylated 1 (human)
def: "A barrier-to-autointegration factor (human) that has been phosphorylated at Ser-4. UniProtKB:O75531, Ser-4, MOD:00046." [PMID:25899223, iPTMnet:O75531]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:25899223). Status=unreviewed.
synonym: "hBANF1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O75531, Ser-4, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:O75531 ! barrier-to-autointegration factor (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens