[Term]
id: PR:000004615
name: beta-secretase 1
def: "A protein that is a translation product of the human BACE1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene. Requested by=Alzforum.
synonym: "ASP2" EXACT []
synonym: "BACE" RELATED Gene-based []
synonym: "Asp 2" EXACT []
synonym: "BACE1" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA1149" RELATED Gene-based []
synonym: "memapsin-2" EXACT []
synonym: "aspartyl protease 2" EXACT []
synonym: "beta-site APP cleaving enzyme 1" EXACT []
synonym: "membrane-associated aspartic protease 2" EXACT []
synonym: "beta-site amyloid precursor protein cleaving enzyme 1" EXACT []
xref: IUPHARobj:2330
is_a: PR:000000001 ! protein

[Term]
id: PR:P56819-1
name: beta-secretase 1 isoform 1 (rat)
def: "A beta-secretase 1 isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rBACE1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P56819-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000039837 ! beta-secretase 1 isoform 1

[Term]
id: PR:P56819
name: beta-secretase 1 (rat)
def: "A beta-secretase 1 that is encoded in the genome of rat." [OMA:P56819, PANTHER:PTHR13683:SF87, PRO:DNx]
comment: Category=organism-gene.
synonym: "Bace" RELATED Gene-based [UniProtKB:P56819]
synonym: "Bace1" RELATED Gene-based [UniProtKB:P56819]
synonym: "rBACE1" EXACT PRO-short-label [PRO:DNx]
synonym: "ASP2 (rat)" EXACT [UniProtKB:P56819]
synonym: "Asp 2 (rat)" EXACT [UniProtKB:P56819]
synonym: "memapsin-2 (rat)" EXACT [UniProtKB:P56819]
synonym: "aspartyl protease 2 (rat)" EXACT [UniProtKB:P56819]
synonym: "beta-site APP cleaving enzyme 1 (rat)" EXACT [UniProtKB:P56819]
synonym: "membrane-associated aspartic protease 2 (rat)" EXACT [UniProtKB:P56819]
synonym: "beta-site amyloid precursor protein cleaving enzyme 1 (rat)" EXACT [UniProtKB:P56819]
xref: UniProtKB:P56819
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000004615 ! beta-secretase 1
relationship: has_gene_template RGD:2191 ! Bace1 (rat)