[Term] id: PR:C0RF67 name: bifunctional purine biosynthesis protein PurH (Brucella melitensis ATCC 23457) def: "A bifunctional purine biosynthesis protein ATIC that is encoded in the genome of Brucella melitensis ATCC 23457." [PRO:CNA] comment: Category=organism-gene. Requested by=IDOBRU. synonym: "purH" RELATED Gene-based [UniProtKB:C0RF67] synonym: "BMEA_A1866" RELATED Gene-based [UniProtKB:C0RF67] synonym: "ATIC (BRUMB)" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:C0RF67 intersection_of: only_in_taxon NCBITaxon:546272 ! Brucella melitensis ATCC 23457 intersection_of: PR:000004423 ! bifunctional purine biosynthesis protein ATIC relationship: has_gene_template EnsemblBacteria:BMEA_A1866 ! purH (Brucella melitensis ATCC 23457) [Term] id: PR:A5VSF8 name: bifunctional purine biosynthesis protein PurH (Brucella ovis ATCC 25840) def: "A bifunctional purine biosynthesis protein ATIC that is encoded in the genome of Brucella ovis ATCC 25840." [PRO:CNA] comment: Category=organism-gene. Requested by=IDOBRU. synonym: "purH" RELATED Gene-based [UniProtKB:A5VSF8] synonym: "BOV_1749" RELATED Gene-based [UniProtKB:A5VSF8] synonym: "ATIC (BRUO2)" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:A5VSF8 intersection_of: only_in_taxon NCBITaxon:444178 ! Brucella ovis ATCC 25840 intersection_of: PR:000004423 ! bifunctional purine biosynthesis protein ATIC relationship: has_gene_template EnsemblBacteria:BOV_1749 ! purH (Brucella ovis ATCC 25840) [Term] id: PR:Q2FZI6 name: bifunctional purine biosynthesis protein PurH (Staphylococcus aureus subsp. aureus NCTC 8325) def: "A bifunctional purine biosynthesis protein ATIC that is encoded in the genome of Staphylococcus aureus subsp. aureus NCTC 8325." [OMA:Q2FZI6, PRO:DNx] comment: Category=organism-gene. synonym: "purH" RELATED Gene-based [UniProtKB:Q2FZI6] synonym: "ATIC (STAA8)" EXACT PRO-short-label [PRO:DNx] synonym: "SAOUHSC_01017" RELATED Gene-based [UniProtKB:Q2FZI6] xref: UniProtKB:Q2FZI6 intersection_of: only_in_taxon NCBITaxon:93061 ! Staphylococcus aureus subsp. aureus NCTC 8325 intersection_of: PR:000004423 ! bifunctional purine biosynthesis protein ATIC relationship: has_gene_template EnsemblBacteria:SAOUHSC_01017 ! purH (Staphylococcus aureus subsp. aureus NCTC 8325) [Term] id: PR:P31939-1 name: bifunctional purine biosynthesis protein ATIC isoform h1 (human) def: "A bifunctional purine biosynthesis protein ATIC (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P31939-1." [PRO:DNx, UniProtKB:P31939] comment: Category=organism-sequence. synonym: "hATIC/iso:h1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P31939-1 is_a: PR:P31939 ! bifunctional purine biosynthesis protein ATIC (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000024869 name: bifunctional purine biosynthesis protein ATIC isoform 1 acetylated 1 def: "A bifunctional purine biosynthesis protein ATIC isoform 1 that has been acetylated at the position equivalent to Lys-287 of the amino acid sequence represented by UniProtKB:P15639-1. Example: UniProtKB:P15639-1, Lys-287, MOD:00064." [EcoCyc:AICARTRANSIMPCYCLO-CPLX] comment: Category=modification. synonym: "ATIC/iso:1/Ac:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000024867 ! bifunctional purine biosynthesis protein ATIC isoform 1 relationship: has_part MOD:00064 ! N6-acetyl-L-lysine [Term] id: PR:P15639 name: bifunctional purine biosynthesis protein PurH (Escherichia coli K-12) def: "A bifunctional purine biosynthesis protein ATIC that is encoded in the genome of Escherichia coli K-12." [OMA:P15639, PRO:DNx] comment: Category=organism-gene. synonym: "purH" RELATED Gene-based [UniProtKB:P15639] synonym: "b4006" RELATED Gene-based [UniProtKB:P15639] synonym: "JW3970" RELATED Gene-based [UniProtKB:P15639] synonym: "Ec-ATIC" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P15639 intersection_of: only_in_taxon NCBITaxon:83333 ! Escherichia coli K-12 intersection_of: PR:000004423 ! bifunctional purine biosynthesis protein ATIC relationship: has_gene_template NCBIGene:948503 ! purH (Escherichia coli K-12) [Term] id: PR:P31335 name: bifunctional purine biosynthesis protein ATIC (chicken) def: "A bifunctional purine biosynthesis protein ATIC that is encoded in the genome of chicken." [PRO:DAN] comment: Category=organism-gene. Requested by=PubChem. synonym: "ATIC" RELATED Gene-based [UniProtKB:P31335] synonym: "PURH" RELATED Gene-based [UniProtKB:P31335] synonym: "chick-ATIC" EXACT PRO-short-label [PRO:DNx] synonym: "AICAR transformylase/inosine monophosphate cyclohydrolase (chicken)" EXACT [UniProtKB:P31335] xref: UniProtKB:P31335 intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus intersection_of: PR:000004423 ! bifunctional purine biosynthesis protein ATIC relationship: has_gene_template CGNC:2606 ! ATIC (chicken) [Term] id: PR:000036656 name: bifunctional purine biosynthesis protein PurH isoform 1 acetylated 1 (Escherichia coli K-12) def: "A bifunctional purine biosynthesis protein ATIC isoform 1 acetylated 1 in Escherichia coli K-12. UniProtKB:P15639-1, Lys-287, MOD:00064." [EcoCyc:AICARTRANSIMPCYCLO-CPLX, PRO:CNA] comment: Category=organism-modification. synonym: "Ec-ATIC/iso:1/Ac:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P15639-1, Lys-287, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] xref: EcoCyc:AICARTRANSIMPCYCLO-CPLX intersection_of: only_in_taxon NCBITaxon:83333 ! Escherichia coli K-12 intersection_of: PR:000024869 ! bifunctional purine biosynthesis protein ATIC isoform 1 acetylated 1 relationship: has_part MOD:00064 ! N6-acetyl-L-lysine [Term] id: PR:000024867 name: bifunctional purine biosynthesis protein ATIC isoform 1 def: "A bifunctional purine biosynthesis protein ATIC that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P15639-1 or a 1:1 ortholog thereof." [PRO:CNA] comment: Category=sequence. synonym: "ATIC/iso:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000004423 ! bifunctional purine biosynthesis protein ATIC [Term] id: PR:O74928 name: bifunctional purine biosynthesis protein ade10 (Schizosaccharomyces pombe 972h-) def: "A bifunctional purine biosynthesis protein ATIC that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:O74928, PANTHER:PTHR11692:SF0, PRO:DNx] comment: Category=organism-gene. synonym: "ade10" RELATED Gene-based [UniProtKB:O74928] synonym: "SPCPB16A4.03c" RELATED Gene-based [UniProtKB:O74928] synonym: "Spom972h-ATIC" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:O74928 intersection_of: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h- intersection_of: PR:000004423 ! bifunctional purine biosynthesis protein ATIC relationship: has_gene_template PomBase:SPCPB16A4.03c ! ade10 (Schizosaccharomyces pombe) [Term] id: PR:P15639-1 name: bifunctional purine biosynthesis protein PurH isoform 1 (Escherichia coli K-12) def: "A bifunctional purine biosynthesis protein ATIC isoform 1 that is encoded in the genome of Escherichia coli K-12." [PRO:CNA] comment: Category=organism-sequence. synonym: "Ec-ATIC/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P15639-1 intersection_of: only_in_taxon NCBITaxon:83333 ! Escherichia coli K-12 intersection_of: PR:000024867 ! bifunctional purine biosynthesis protein ATIC isoform 1 [Term] id: PR:Q9CWJ9 name: bifunctional purine biosynthesis protein ATIC (mouse) def: "A bifunctional purine biosynthesis protein ATIC that is encoded in the genome of mouse." [OMA:Q9CWJ9, PRO:DNx] comment: Category=organism-gene. synonym: "Atic" RELATED Gene-based [UniProtKB:Q9CWJ9] synonym: "Purh" RELATED Gene-based [UniProtKB:Q9CWJ9] synonym: "mATIC" EXACT PRO-short-label [PRO:DNx] synonym: "ATIC (mouse)" EXACT [UniProtKB:Q9CWJ9] synonym: "AICAR transformylase/inosine monophosphate cyclohydrolase (mouse)" EXACT [UniProtKB:Q9CWJ9] xref: UniProtKB:Q9CWJ9 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000004423 ! bifunctional purine biosynthesis protein ATIC relationship: has_gene_template MGI:1351352 ! Atic (mouse) [Term] id: PR:A9M854 name: bifunctional purine biosynthesis protein PurH (Brucella canis ATCC 23365) def: "A bifunctional purine biosynthesis protein ATIC that is encoded in the genome of Brucella canis ATCC 23365." [PRO:CNA] comment: Category=organism-gene. Requested by=IDOBRU. synonym: "purH" RELATED Gene-based [UniProtKB:A9M854] synonym: "BCAN_A1854" RELATED Gene-based [UniProtKB:A9M854] synonym: "ATIC (BRUC2)" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:A9M854 intersection_of: only_in_taxon NCBITaxon:483179 ! Brucella canis ATCC 23365 intersection_of: PR:000004423 ! bifunctional purine biosynthesis protein ATIC relationship: has_gene_template EnsemblBacteria:BCAN_A1854 ! purH (Brucella canis ATCC 23365) [Term] id: PR:Q86L14 name: bifunctional purine biosynthesis protein purH (Dictyostelium discoideum) def: "A bifunctional purine biosynthesis protein ATIC that is encoded in the genome of Dictyostelium discoideum." [OMA:Q86L14, PRO:DNx] comment: Category=organism-gene. synonym: "purH" RELATED Gene-based [UniProtKB:Q86L14] synonym: "Dicty-ATIC" EXACT PRO-short-label [PRO:DNx] synonym: "DDB_G0277087" RELATED Gene-based [UniProtKB:Q86L14] xref: UniProtKB:Q86L14 intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum intersection_of: PR:000004423 ! bifunctional purine biosynthesis protein ATIC relationship: has_gene_template dictyBase:DDB_G0277087 ! purH (Dictyostelium discoideum) [Term] id: PR:Q57B71 name: bifunctional purine biosynthesis protein PurH (Brucella abortus bv. 1 str. 9-941) def: "A bifunctional purine biosynthesis protein ATIC that is encoded in the genome of Brucella abortus bv. 1 str. 9-941." [PRO:CNA] comment: Category=organism-gene. Requested by=IDOBRU. synonym: "purH" RELATED Gene-based [UniProtKB:Q57B71] synonym: "BruAb1_1796" RELATED Gene-based [UniProtKB:Q57B71] synonym: "ATIC (BRUAB)" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q57B71 intersection_of: only_in_taxon NCBITaxon:262698 ! Brucella abortus bv. 1 str. 9-941 intersection_of: PR:000004423 ! bifunctional purine biosynthesis protein ATIC relationship: has_gene_template EnsemblBacteria:BruAb1_1796 ! purH (Brucella abortus bv. 1 str. 9-941) [Term] id: PR:O35567 name: bifunctional purine biosynthesis protein ATIC (rat) def: "A bifunctional purine biosynthesis protein ATIC that is encoded in the genome of rat." [OMA:O35567, PANTHER:PTHR11692:SF0, PRO:DNx] comment: Category=organism-gene. synonym: "Atic" RELATED Gene-based [UniProtKB:O35567] synonym: "Purh" RELATED Gene-based [UniProtKB:O35567] synonym: "rATIC" EXACT PRO-short-label [PRO:DNx] synonym: "ATIC (rat)" EXACT [UniProtKB:O35567] synonym: "AICAR transformylase/inosine monophosphate cyclohydrolase (rat)" EXACT [UniProtKB:O35567] xref: UniProtKB:O35567 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000004423 ! bifunctional purine biosynthesis protein ATIC relationship: has_gene_template RGD:70879 ! Atic (rat) [Term] id: PR:A5I5V9 name: bifunctional purine biosynthesis protein PurH (Clostridium botulinum A str. Hall) def: "A bifunctional purine biosynthesis protein ATIC that is encoded in the genome of Clostridium botulinum A str. Hall." [OMA:A5I5V9, PRO:DNx] comment: Category=organism-gene. Note: Additional NCBIGenes (GeneIDs) listed in the UniProtKB entry have been reviewed and removed by PRO:DNx. synonym: "purH" RELATED Gene-based [UniProtKB:A5I5V9] synonym: "CBO2873" RELATED Gene-based [UniProtKB:A5I5V9] synonym: "CLC_2771" RELATED Gene-based [UniProtKB:A5I5V9] synonym: "ATIC (CLOBH)" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:A5I5V9 intersection_of: only_in_taxon NCBITaxon:441771 ! Clostridium botulinum A str. Hall intersection_of: PR:000004423 ! bifunctional purine biosynthesis protein ATIC relationship: has_gene_template NCBIGene:5399190 ! purH (Clostridium botulinum A str. Hall) [Term] id: PR:P67540 name: bifunctional purine biosynthesis protein PurH (Brucella suis 1330) def: "A bifunctional purine biosynthesis protein ATIC that is encoded in the genome of Brucella suis 1330." [PRO:CNA] comment: Category=organism-gene. Requested by=IDOBRU. synonym: "purH" RELATED Gene-based [UniProtKB:P67540] synonym: "BR1816" RELATED Gene-based [UniProtKB:P67540] synonym: "ATIC (BRUSU)" EXACT PRO-short-label [PRO:DNx] synonym: "BS1330_I1810" RELATED Gene-based [UniProtKB:P67540] xref: UniProtKB:P67540 intersection_of: only_in_taxon NCBITaxon:204722 ! Brucella suis 1330 intersection_of: PR:000004423 ! bifunctional purine biosynthesis protein ATIC relationship: has_gene_template EnsemblBacteria:BR1816 ! purH (Brucella suis 1330) [Term] id: PR:P31939-2 name: bifunctional purine biosynthesis protein ATIC isoform h2 (human) def: "A bifunctional purine biosynthesis protein ATIC (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P31939-2." [PRO:DNx, UniProtKB:P31939] comment: Category=organism-sequence. synonym: "hATIC/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P31939-2 is_a: PR:P31939 ! bifunctional purine biosynthesis protein ATIC (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P31939 name: bifunctional purine biosynthesis protein ATIC (human) def: "A bifunctional purine biosynthesis protein ATIC that is encoded in the genome of human." [PRO:DNx, UniProtKB:P31939] comment: Category=organism-gene. synonym: "ATIC" RELATED Gene-based [UniProtKB:P31939] synonym: "PURH" RELATED Gene-based [UniProtKB:P31939] synonym: "hATIC" EXACT PRO-short-label [PRO:DNx] synonym: "OK/SW-cl.86" RELATED Gene-based [UniProtKB:P31939] synonym: "AICAR transformylase/inosine monophosphate cyclohydrolase (human)" EXACT [UniProtKB:P31939] xref: Reactome:R-HSA-62506 "PR:P31939 located_in GO:0005829" xref: UniProtKB:P31939 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000004423 ! bifunctional purine biosynthesis protein ATIC relationship: has_gene_template HGNC:794 ! ATIC (human) [Term] id: PR:000004423 name: bifunctional purine biosynthesis protein ATIC def: "A protein that is a translation product of the human ATIC gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "ATIC" EXACT PRO-short-label [PRO:DNx] synonym: "PURH" RELATED Gene-based [] synonym: "OK/SW-cl.86" RELATED Gene-based [] synonym: "AICAR transformylase/inosine monophosphate cyclohydrolase" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:A9WWU1 name: bifunctional purine biosynthesis protein PurH (Brucella suis ATCC 23445) def: "A bifunctional purine biosynthesis protein ATIC that is encoded in the genome of Brucella suis ATCC 23445." [PRO:CNA] comment: Category=organism-gene. Requested by=IDOBRU. synonym: "purH" RELATED Gene-based [UniProtKB:A9WWU1] synonym: "BSUIS_B1294" RELATED Gene-based [UniProtKB:A9WWU1] synonym: "ATIC (BRUSI)" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:A9WWU1 intersection_of: only_in_taxon NCBITaxon:470137 ! Brucella suis ATCC 23445 intersection_of: PR:000004423 ! bifunctional purine biosynthesis protein ATIC relationship: has_gene_template EnsemblBacteria:BSUIS_B1294 ! purH (Brucella suis ATCC 23445) [Term] id: PR:Q2YLH0 name: bifunctional purine biosynthesis protein PurH (Brucella abortus 2308) def: "A bifunctional purine biosynthesis protein ATIC that is encoded in the genome of Brucella abortus 2308." [PRO:CNA] comment: Category=organism-gene. Requested by=IDOBRU. synonym: "purH" RELATED Gene-based [UniProtKB:Q2YLH0] synonym: "BAB1_1824" RELATED Gene-based [UniProtKB:Q2YLH0] synonym: "ATIC (BRUA2)" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q2YLH0 intersection_of: only_in_taxon NCBITaxon:359391 ! Brucella abortus 2308 intersection_of: PR:000004423 ! bifunctional purine biosynthesis protein ATIC relationship: has_gene_template EnsemblBacteria:BAB1_1824 ! purH (Brucella abortus 2308)