[Term]
id: PR:000004400
name: cyclic AMP-dependent transcription factor ATF-4
def: "A protein that is a translation product of the human ATF4 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "ATF4" EXACT PRO-short-label [PRO:DNx]
synonym: "C/ATF" EXACT []
synonym: "CREB2" RELATED Gene-based []
synonym: "TXREB" RELATED Gene-based []
synonym: "CREB-2" RELATED []
synonym: "TaxREB67" EXACT []
synonym: "TaxREB67 homolog" EXACT []
synonym: "C/EBP-related ATF" EXACT []
synonym: "DNA-binding protein TAXREB67" EXACT []
synonym: "activating transcription factor 4" EXACT []
synonym: "cAMP-dependent transcription factor ATF-4" EXACT []
synonym: "cAMP-responsive element-binding protein 2" RELATED []
synonym: "cyclic AMP-responsive element-binding protein 2" RELATED []
synonym: "Tax-responsive enhancer element-binding protein 67" EXACT []
synonym: "Tax-responsive enhancer element-binding protein 67 homolog" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:P18848
name: cyclic AMP-dependent transcription factor ATF-4 (human)
def: "A cyclic AMP-dependent transcription factor ATF-4 that is encoded in the genome of human." [PRO:PD]
comment: Category=organism-gene. Requested by=PubChem.
synonym: "ATF4" RELATED Gene-based [UniProtKB:P18848]
synonym: "CREB2" RELATED Gene-based [UniProtKB:P18848]
synonym: "TXREB" RELATED Gene-based [UniProtKB:P18848]
synonym: "hATF4" EXACT PRO-short-label [PRO:DNx]
synonym: "CREB-2 (human)" BROAD [UniProtKB:P18848]
synonym: "TaxREB67 (human)" EXACT [UniProtKB:P18848]
synonym: "activating transcription factor 4 (human)" EXACT [UniProtKB:P18848]
synonym: "cAMP-dependent transcription factor ATF-4 (human)" EXACT [UniProtKB:P18848]
synonym: "cAMP-responsive element-binding protein 2 (human)" BROAD [UniProtKB:P18848]
synonym: "cyclic AMP-responsive element-binding protein 2 (human)" BROAD [UniProtKB:P18848]
synonym: "Tax-responsive enhancer element-binding protein 67 (human)" EXACT [UniProtKB:P18848]
xref: Reactome:R-HSA-381016 "PR:P18848 located_in GO:0005654"
xref: UniProtKB:P18848
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000004400 ! cyclic AMP-dependent transcription factor ATF-4
relationship: has_gene_template HGNC:786 ! ATF4 (human)

[Term]
id: PR:P18848-1
name: cyclic AMP-dependent transcription factor ATF-4 isoform 1 (human)
def: "A cyclic AMP-dependent transcription factor ATF-4 isoform 1 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hATF4/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P18848-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000028554 ! cyclic AMP-dependent transcription factor ATF-4 isoform 1

[Term]
id: PR:000028557
name: cyclic AMP-dependent transcription factor ATF-4 acetylated 1 (human)
def: "A cyclic AMP-dependent transcription factor ATF-4 acetylated 1 in human. UniProtKB:P18848, Lys-311, MOD:00064." [KAT:P18848, PMID:16219772, PRO:PD]
comment: Category=organism-modification. Acetylase=("EP300"; PR:000007102).
synonym: "hATF4/Ac:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P18848, Lys-311, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000028556 ! cyclic AMP-dependent transcription factor ATF-4 acetylated 1
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine