[Term]
id: PR:Q9QWY8
name: Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (mouse)
def: "An Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 that is encoded in the genome of mouse." [OMA:Q9QWY8, PRO:DNx]
comment: Category=organism-gene.
synonym: "Asap1" RELATED Gene-based [UniProtKB:Q9QWY8]
synonym: "Ddef1" RELATED Gene-based [UniProtKB:Q9QWY8]
synonym: "Shag1" RELATED Gene-based [UniProtKB:Q9QWY8]
synonym: "mASAP1" EXACT PRO-short-label [PRO:DNx]
synonym: "Kiaa1249" RELATED Gene-based [UniProtKB:Q9QWY8]
synonym: "DEF-1 (mouse)" EXACT [UniProtKB:Q9QWY8]
synonym: "PIP2-dependent ARF1 GAP (mouse)" EXACT [UniProtKB:Q9QWY8]
synonym: "ARF GTPase-activating protein 1 (mouse)" EXACT [UniProtKB:Q9QWY8]
synonym: "differentiation-enhancing factor 1 (mouse)" EXACT [UniProtKB:Q9QWY8]
synonym: "development and differentiation-enhancing factor 1 (mouse)" EXACT [UniProtKB:Q9QWY8]
synonym: "ADP-ribosylation factor-directed GTPase-activating protein 1 (mouse)" EXACT [UniProtKB:Q9QWY8]
synonym: "130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein (mouse)" EXACT [UniProtKB:Q9QWY8]
xref: UniProtKB:Q9QWY8
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000004338 ! Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
relationship: has_gene_template MGI:1342335 ! Asap1 (mouse)

[Term]
id: PR:Q9QWY8-3
name: Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform m3 (mouse)
def: "An Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9QWY8-3." [PRO:DNx, UniProtKB:Q9QWY8]
comment: Category=organism-sequence.
synonym: "mASAP1/iso:m3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9QWY8-3
is_a: PR:Q9QWY8 ! Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q9QWY8-1
name: Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform m1 (mouse)
def: "An Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9QWY8-1." [PRO:DNx, UniProtKB:Q9QWY8]
comment: Category=organism-sequence.
synonym: "mASAP1/iso:m1" EXACT PRO-short-label [PRO:DNx]
synonym: "Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform ASAP1a (mouse)" EXACT [UniProtKB:Q9QWY8]
synonym: "Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform SHAG1a (mouse)" EXACT [UniProtKB:Q9QWY8]
xref: UniProtKB:Q9QWY8-1
is_a: PR:Q9QWY8 ! Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000004338
name: Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
def: "A protein that is a translation product of the human ASAP1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "PAG2" RELATED Gene-based []
synonym: "ASAP1" EXACT PRO-short-label [PRO:DNx]
synonym: "DDEF1" RELATED Gene-based []
synonym: "DEF-1" EXACT []
synonym: "Shag1" RELATED Gene-based []
synonym: "KIAA1249" RELATED Gene-based []
synonym: "PIP2-dependent ARF1 GAP" EXACT []
synonym: "ARF GTPase-activating protein 1" EXACT []
synonym: "differentiation-enhancing factor 1" EXACT []
synonym: "development and differentiation-enhancing factor 1" EXACT []
synonym: "ADP-ribosylation factor-directed GTPase-activating protein 1" EXACT []
synonym: "130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase-activating protein" EXACT []
synonym: "130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q9QWY8-2
name: Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform m2 (mouse)
def: "An Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9QWY8-2." [PRO:DNx, UniProtKB:Q9QWY8]
comment: Category=organism-sequence.
synonym: "mASAP1/iso:m2" EXACT PRO-short-label [PRO:DNx]
synonym: "Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform ASAP1b (mouse)" EXACT [UniProtKB:Q9QWY8]
synonym: "Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform SHAG1b (mouse)" EXACT [UniProtKB:Q9QWY8]
xref: UniProtKB:Q9QWY8-2
is_a: PR:Q9QWY8 ! Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q9QWY8-4
name: Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform m4 (mouse)
def: "An Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9QWY8-4." [PRO:DNx, UniProtKB:Q9QWY8]
comment: Category=organism-sequence.
synonym: "mASAP1/iso:m4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9QWY8-4
is_a: PR:Q9QWY8 ! Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000049740
name: Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform m1 phosphorylated 1 (mouse)
def: "An Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform m1 (mouse) that has been phosphorylated on Tyr-308 and Tyr-782. UniProtKB:Q9QWY8-1, Tyr-308/Tyr-782, MOD:00048." [PMID:12771146, PRO:KRC]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:12771146). Kinase=("Ptkb2"; PR:Q9QVP9; Tyr-308). Kinase=("Ptkb2"; PR:Q9QVP9; Tyr-782).
synonym: "mASAP1/iso:m1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "ASAP1 phosphorylated 1" RELATED []
synonym: "UniProtKB:Q9QWY8-1, Tyr-308/Tyr-782, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:Q9QWY8-1 ! Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform m1 (mouse)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000049741
name: Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform m1 unphosphorylated 1 (mouse)
def: "An Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform m1 (mouse) that lacks phosphorylated Tyr-308 and Tyr-782. UniProtKB:Q9QWY8-1, Tyr-308/Tyr-782, PR:000026291." [PMID:12771146, PRO:KRC]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:12771146].
synonym: "mASAP1/iso:m1/UnPhos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "ASAP1 unphosphorylated 1" RELATED []
synonym: "UniProtKB:Q9QWY8-1, Tyr-308/Tyr-782, PR:000026291" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:Q9QWY8-1 ! Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform m1 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000045553
name: Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform m2 Src-phosphorylated form (mouse)
def: "An Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform m2 (mouse) that has been phosphorylated on Tyr residues within Src phosphorylation sites. Example: UniProtKB:Q9QWY8-2, Tyr-782, MOD:00048." [PMID:17893324, PMID:9819391, PRO:KRC]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:9819391]. Evidence=(ECO:0000006, based on PMID:17893324].
synonym: "mASAP1/iso:m2/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "ASAP1b phosphorylated 1" EXACT []
synonym: "UniProtKB:Q9QWY8-2, Tyr-782, MOD:00048" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q9QWY8-2 ! Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform m2 (mouse)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus