[Term]
id: PR:P55145
name: mesencephalic astrocyte-derived neurotrophic factor (human)
def: "A protein ARMET that is encoded in the genome of human." [PRO:DNx, UniProtKB:P55145]
comment: Category=organism-gene.
synonym: "ARP" RELATED Gene-based [UniProtKB:P55145]
synonym: "MANF" RELATED Gene-based [UniProtKB:P55145]
synonym: "ARMET" RELATED Gene-based [UniProtKB:P55145]
synonym: "hMANF" EXACT PRO-short-label [PRO:DNx]
synonym: "protein ARMET (human)" EXACT [UniProtKB:P55145]
synonym: "arginine-rich protein (human)" EXACT [UniProtKB:P55145]
xref: UniProtKB:P55145
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000004300 ! protein ARMET
relationship: has_gene_template HGNC:15461 ! MANF (human)

[Term]
id: PR:Q9XZ63
name: mesencephalic astrocyte-derived neurotrophic factor homolog (fruit fly)
def: "A protein ARMET that is encoded in the genome of fruit fly." [OMA:Q9XZ63, PRO:DNx]
comment: Category=organism-gene.
synonym: "Manf" RELATED Gene-based [UniProtKB:Q9XZ63]
synonym: "CG7013" RELATED Gene-based [UniProtKB:Q9XZ63]
synonym: "DmMANF" EXACT [UniProtKB:Q9XZ63]
synonym: "ARP-like" RELATED Gene-based [UniProtKB:Q9XZ63]
synonym: "fly-MANF" EXACT PRO-short-label [PRO:DNx]
synonym: "MANF/CDNF-like protein (fruit fly)" EXACT [UniProtKB:Q9XZ63]
xref: UniProtKB:Q9XZ63
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
intersection_of: PR:000004300 ! protein ARMET
relationship: has_gene_template FlyBase:FBgn0027095 ! Manf (fruit fly)

[Term]
id: PR:Q9CXI5
name: mesencephalic astrocyte-derived neurotrophic factor (mouse)
def: "A protein ARMET that is encoded in the genome of mouse." [OMA:Q9CXI5, PRO:DNx]
comment: Category=organism-gene.
synonym: "Manf" RELATED Gene-based [UniProtKB:Q9CXI5]
synonym: "Armet" RELATED Gene-based [UniProtKB:Q9CXI5]
synonym: "mMANF" EXACT PRO-short-label [PRO:DNx]
synonym: "protein ARMET (mouse)" EXACT [UniProtKB:Q9CXI5]
synonym: "arginine-rich protein (mouse)" EXACT [UniProtKB:Q9CXI5]
xref: UniProtKB:Q9CXI5
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000004300 ! protein ARMET
relationship: has_gene_template MGI:1922090 ! Manf (mouse)

[Term]
id: PR:000019050
name: protein ARMET, signal peptide removed form
def: "A protein ARMET that has had the signal peptide removed." [PRO:DNx]
comment: Category=modification.
synonym: "ARMET/SigPep-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000004300 ! protein ARMET
intersection_of: lacks_part SO:0000418 ! signal_peptide

[Term]
id: PR:000048289
name: mesencephalic astrocyte-derived neurotrophic factor, signal peptide removed form (human)
def: "A mesencephalic astrocyte-derived neurotrophic factor (human) that has had the signal peptide removed. UniProtKB:P55145, 25-182." [PRO:DNx, Reactome:R-HSA-8862946, Reactome:R-HSA-8862958]
comment: Category=organism-modification.
synonym: "hMANF/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000002305" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P55145, 25-182" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-8862946 "PR:000048289 located_in GO:0005829"
xref: Reactome:R-HSA-8862958 "PR:000048289 located_in GO:0005576"
intersection_of: PR:P55145 ! mesencephalic astrocyte-derived neurotrophic factor (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P0C5H9
name: mesencephalic astrocyte-derived neurotrophic factor (rat)
def: "A protein ARMET that is encoded in the genome of rat." [OMA:P0C5H9, PANTHER:PTHR12990:SF4, PRO:DNx]
comment: Category=organism-gene.
synonym: "Manf" RELATED Gene-based [UniProtKB:P0C5H9]
synonym: "Armet" RELATED Gene-based [UniProtKB:P0C5H9]
synonym: "rMANF" EXACT PRO-short-label [PRO:DNx]
synonym: "protein ARMET (rat)" EXACT [UniProtKB:P0C5H9]
synonym: "arginine-rich protein (rat)" EXACT [UniProtKB:P0C5H9]
xref: UniProtKB:P0C5H9
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000004300 ! protein ARMET
relationship: has_gene_template RGD:1307252 ! Manf (rat)

[Term]
id: PR:000004300
name: protein ARMET
def: "A protein that is a translation product of the human MANF gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "ARP" RELATED Gene-based []
synonym: "MANF" EXACT PRO-short-label [PRO:DNx]
synonym: "ARMET" RELATED Gene-based []
synonym: "arginine-rich protein" EXACT []
is_a: PR:000000001 ! protein