[Term]
id: PR:Q8K4I3
name: Rho guanine nucleotide exchange factor 6 (mouse)
def: "A Rho guanine nucleotide exchange factor 6 that is encoded in the genome of mouse." [OMA:Q8K4I3, PRO:DNx]
comment: Category=organism-gene.
synonym: "Arhgef6" RELATED Gene-based [UniProtKB:Q8K4I3]
synonym: "mARHGEF6" EXACT PRO-short-label [PRO:DNx]
synonym: "alpha-PIX (mouse)" EXACT [UniProtKB:Q8K4I3]
synonym: "Rac/Cdc42 guanine nucleotide exchange factor 6 (mouse)" EXACT [UniProtKB:Q8K4I3]
xref: UniProtKB:Q8K4I3
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000004259 ! Rho guanine nucleotide exchange factor 6
relationship: has_gene_template MGI:1920591 ! Arhgef6 (mouse)

[Term]
id: PR:000004259
name: Rho guanine nucleotide exchange factor 6
def: "A protein that is a translation product of the human ARHGEF6 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "PIXA" RELATED Gene-based []
synonym: "COOL2" RELATED Gene-based []
synonym: "COOL-2" EXACT []
synonym: "ARHGEF6" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA0006" RELATED Gene-based []
synonym: "alpha-Pix" EXACT []
synonym: "PAK-interacting exchange factor alpha" EXACT []
synonym: "rac/Cdc42 guanine nucleotide exchange factor 6" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q15052-1
name: Rho guanine nucleotide exchange factor 6 isoform h1 (human)
def: "A Rho guanine nucleotide exchange factor 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15052-1." [PRO:DNx, UniProtKB:Q15052]
comment: Category=organism-sequence.
synonym: "hARHGEF6/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q15052-1
is_a: PR:Q15052 ! Rho guanine nucleotide exchange factor 6 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q15052-2
name: Rho guanine nucleotide exchange factor 6 isoform h2 (human)
def: "A Rho guanine nucleotide exchange factor 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15052-2." [PRO:DNx, UniProtKB:Q15052]
comment: Category=organism-sequence.
synonym: "hARHGEF6/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q15052-2
is_a: PR:Q15052 ! Rho guanine nucleotide exchange factor 6 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q5XXR3
name: Rho guanine nucleotide exchange factor 6 (rat)
def: "A Rho guanine nucleotide exchange factor 6 that is encoded in the genome of rat." [OMA:Q5XXR3, PANTHER:PTHR22826:SF18, PRO:DNx]
comment: Category=organism-gene.
synonym: "Arhgef6" RELATED Gene-based [UniProtKB:Q5XXR3]
synonym: "rARHGEF6" EXACT PRO-short-label [PRO:DNx]
synonym: "Rac/Cdc42 guanine nucleotide exchange factor 6 (rat)" EXACT [UniProtKB:Q5XXR3]
xref: UniProtKB:Q5XXR3
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000004259 ! Rho guanine nucleotide exchange factor 6
relationship: has_gene_template RGD:1359674 ! Arhgef6 (rat)

[Term]
id: PR:Q5ZLR6
name: Rho guanine nucleotide exchange factor 6 (chicken)
def: "A Rho guanine nucleotide exchange factor 6 that is encoded in the genome of chicken." [OMA:Q5ZLR6, PANTHER:PTHR22826:SF18, PRO:DNx]
comment: Category=organism-gene.
synonym: "ARHGEF6" RELATED Gene-based [UniProtKB:Q5ZLR6]
synonym: "RCJMB04_5b15" RELATED Gene-based [UniProtKB:Q5ZLR6]
synonym: "chick-ARHGEF6" EXACT PRO-short-label [PRO:DNx]
synonym: "Rac/Cdc42 guanine nucleotide exchange factor 6 (chicken)" EXACT [UniProtKB:Q5ZLR6]
xref: UniProtKB:Q5ZLR6
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000004259 ! Rho guanine nucleotide exchange factor 6
relationship: has_gene_template NCBIGene:422247 ! ARHGEF6 (chicken)

[Term]
id: PR:Q15052
name: Rho guanine nucleotide exchange factor 6 (human)
def: "A Rho guanine nucleotide exchange factor 6 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q15052]
comment: Category=organism-gene.
synonym: "PIXA" RELATED Gene-based [UniProtKB:Q15052]
synonym: "COOL2" RELATED Gene-based [UniProtKB:Q15052]
synonym: "ARHGEF6" RELATED Gene-based [UniProtKB:Q15052]
synonym: "KIAA0006" RELATED Gene-based [UniProtKB:Q15052]
synonym: "hARHGEF6" EXACT PRO-short-label [PRO:DNx]
synonym: "COOL-2 (human)" EXACT [UniProtKB:Q15052]
synonym: "alpha-Pix (human)" EXACT [UniProtKB:Q15052]
synonym: "PAK-interacting exchange factor alpha (human)" EXACT [UniProtKB:Q15052]
synonym: "Rac/Cdc42 guanine nucleotide exchange factor 6 (human)" EXACT [UniProtKB:Q15052]
xref: Reactome:R-HSA-195017 "PR:Q15052 located_in GO:0005829"
xref: UniProtKB:Q15052
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000004259 ! Rho guanine nucleotide exchange factor 6
relationship: has_gene_template HGNC:685 ! ARHGEF6 (human)