[Term]
id: PR:000046108
name: brefeldin A-inhibited guanine nucleotide-exchange protein 1 phosphorylated 1 (human)
def: "A brefeldin A-inhibited guanine nucleotide-exchange protein 1 (human) that has been phosphorylated at Ser-883. UniProtKB:Q9Y6D6, Ser-883, MOD:00046." [PMID:16467138, iPTMnet:Q9Y6D6]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:16467138). Status=unreviewed.
synonym: "hARFGEF1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9Y6D6, Ser-883, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:Q9Y6D6 ! brefeldin A-inhibited guanine nucleotide-exchange protein 1 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9Y6D6
name: brefeldin A-inhibited guanine nucleotide-exchange protein 1 (human)
def: "A brefeldin A-inhibited guanine nucleotide-exchange protein 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9Y6D6]
comment: Category=organism-gene.
synonym: "BIG1" RELATED Gene-based [UniProtKB:Q9Y6D6]
synonym: "ARFGEF1" RELATED Gene-based [UniProtKB:Q9Y6D6]
synonym: "ARFGEP1" RELATED Gene-based [UniProtKB:Q9Y6D6]
synonym: "hARFGEF1" EXACT PRO-short-label [PRO:DNx]
synonym: "p200 ARF-GEP1 (human)" EXACT [UniProtKB:Q9Y6D6]
synonym: "brefeldin A-inhibited GEP 1 (human)" EXACT [UniProtKB:Q9Y6D6]
synonym: "p200 ARF guanine nucleotide exchange factor (human)" EXACT [UniProtKB:Q9Y6D6]
synonym: "ADP-ribosylation factor guanine nucleotide-exchange factor 1 (human)" EXACT [UniProtKB:Q9Y6D6]
xref: UniProtKB:Q9Y6D6
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000004209 ! brefeldin A-inhibited guanine nucleotide-exchange protein 1
relationship: has_gene_template HGNC:15772 ! ARFGEF1 (human)

[Term]
id: PR:000004209
name: brefeldin A-inhibited guanine nucleotide-exchange protein 1
def: "A protein that is a translation product of the human ARFGEF1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "BIG1" RELATED Gene-based []
synonym: "ARFGEF1" EXACT PRO-short-label [PRO:DNx]
synonym: "ARFGEP1" RELATED Gene-based []
synonym: "p200 ARF-GEP1" EXACT []
synonym: "brefeldin A-inhibited GEP 1" EXACT []
synonym: "p200 ARF guanine nucleotide exchange factor" EXACT []
synonym: "ADP-ribosylation factor guanine nucleotide-exchange factor 1" EXACT []
is_a: PR:000000001 ! protein