[Term]
id: PR:P41181-1
name: aquaporin-2 isoform 1 (human)
def: "An aquaporin-2 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hAQP2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P41181-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000039411 ! aquaporin-2 isoform 1

[Term]
id: PR:000004182
name: aquaporin-2
def: "An aquaporin protein that is a translation product of the human AQP2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "AQP2" EXACT PRO-short-label [PRO:DNx]
synonym: "AQP-2" EXACT []
synonym: "AQP-CD" EXACT []
synonym: "WCH-CD" EXACT []
synonym: "aquaporin-CD" EXACT []
synonym: "ADH water channel" EXACT []
synonym: "collecting duct water channel protein" EXACT []
synonym: "water channel protein for renal collecting duct" EXACT []
xref: IUPHARobj:689
is_a: PR:000044672 ! aquaporin protein

[Term]
id: PR:P56402-1
name: aquaporin-2 isoform 1 (mouse)
def: "An aquaporin-2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mAQP2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P56402-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000039411 ! aquaporin-2 isoform 1

[Term]
id: PR:P34080-1
name: aquaporin-2 isoform 1 (rat)
def: "An aquaporin-2 isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rAQP2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P34080-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000039411 ! aquaporin-2 isoform 1

[Term]
id: PR:P56402
name: aquaporin-2 (mouse)
def: "An aquaporin-2 that is encoded in the genome of mouse." [OMA:P56402, PRO:DNx]
comment: Category=organism-gene.
synonym: "cph" RELATED Gene-based [UniProtKB:P56402]
synonym: "Aqp2" RELATED Gene-based [UniProtKB:P56402]
synonym: "mAQP2" EXACT PRO-short-label [PRO:DNx]
synonym: "AQP-2 (mouse)" EXACT [UniProtKB:P56402]
synonym: "AQP-CD (mouse)" EXACT [UniProtKB:P56402]
synonym: "WCH-CD (mouse)" EXACT [UniProtKB:P56402]
synonym: "aquaporin-CD (mouse)" EXACT [UniProtKB:P56402]
synonym: "ADH water channel (mouse)" EXACT [UniProtKB:P56402]
synonym: "collecting duct water channel protein (mouse)" EXACT [UniProtKB:P56402]
synonym: "water channel protein for renal collecting duct (mouse)" EXACT [UniProtKB:P56402]
xref: UniProtKB:P56402
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000004182 ! aquaporin-2
relationship: has_gene_template MGI:1096865 ! Aqp2 (mouse)

[Term]
id: PR:P34080
name: aquaporin-2 (rat)
def: "An aquaporin-2 that is encoded in the genome of rat." [OMA:P34080, PRO:DNx]
comment: Category=organism-gene.
synonym: "Aqp2" RELATED Gene-based [UniProtKB:P34080]
synonym: "rAQP2" EXACT PRO-short-label [PRO:DNx]
synonym: "AQP-2 (rat)" EXACT [UniProtKB:P34080]
synonym: "AQP-CD (rat)" EXACT [UniProtKB:P34080]
synonym: "WCH-CD (rat)" EXACT [UniProtKB:P34080]
synonym: "aquaporin-CD (rat)" EXACT [UniProtKB:P34080]
synonym: "ADH water channel (rat)" EXACT [UniProtKB:P34080]
synonym: "collecting duct water channel protein (rat)" EXACT [UniProtKB:P34080]
synonym: "water channel protein for renal collecting duct (rat)" EXACT [UniProtKB:P34080]
xref: UniProtKB:P34080
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000004182 ! aquaporin-2
relationship: has_gene_template RGD:2142 ! Aqp2 (rat)

[Term]
id: PR:000045775
name: aquaporin-2 phosphorylated 1 (human)
def: "An aquaporin-2 (human) that has been phosphorylated at Ser-256. UniProtKB:P41181, Ser-256, MOD:00046." [PMID:12194985, iPTMnet:P41181]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:12194985). Status=unreviewed.
synonym: "hAQP2/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P41181, Ser-256, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-432222 "PR:000045775 located_in GO:0030658"
xref: Reactome:R-HSA-432231 "PR:000045775 located_in GO:0005886"
is_a: PR:P41181 ! aquaporin-2 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P41181
name: aquaporin-2 (human)
def: "An aquaporin-2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P41181]
comment: Category=organism-gene.
synonym: "AQP2" RELATED Gene-based [UniProtKB:P41181]
synonym: "hAQP2" EXACT PRO-short-label [PRO:DNx]
synonym: "AQP-2 (human)" EXACT [UniProtKB:P41181]
synonym: "AQP-CD (human)" EXACT [UniProtKB:P41181]
synonym: "WCH-CD (human)" EXACT [UniProtKB:P41181]
synonym: "aquaporin-CD (human)" EXACT [UniProtKB:P41181]
synonym: "ADH water channel (human)" EXACT [UniProtKB:P41181]
synonym: "collecting duct water channel protein (human)" EXACT [UniProtKB:P41181]
synonym: "water channel protein for renal collecting duct (human)" EXACT [UniProtKB:P41181]
xref: Reactome:R-HSA-432215 "PR:P41181 located_in GO:0030658"
xref: UniProtKB:P41181
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000004182 ! aquaporin-2
relationship: has_gene_template HGNC:634 ! AQP2 (human)

[Term]
id: PR:000039411
name: aquaporin-2 isoform 1
def: "An aquaporin-2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P41181-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "AQP2/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000004182 ! aquaporin-2