[Term]
id: PR:000046354
name: amyloid beta precursor like protein 2, signal peptide removed form (human)
def: "An amyloid beta precursor like protein 2 (human) that has had the signal peptide removed. UniProtKB:Q06481, 32-763." [PRO:DNx, Reactome:R-HSA-8848898, Reactome:R-HSA-8848902]
comment: Category=organism-modification.
synonym: "PRO_0000000207" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hAPLP2/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q06481, 32-763" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-8848898 "PR:000046354 located_in GO:0031092"
xref: Reactome:R-HSA-8848902 "PR:000046354 located_in GO:0005886"
xref: Reactome:R-HSA-8956784 "PR:000046354 located_in GO:0005788"
intersection_of: PR:Q06481 ! amyloid beta precursor like protein 2 (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q06481
name: amyloid beta precursor like protein 2 (human)
def: "An amyloid beta precursor like protein 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q06481]
comment: Category=organism-gene.
synonym: "APLP2" RELATED Gene-based [UniProtKB:Q06481]
synonym: "APPL2" RELATED Gene-based [UniProtKB:Q06481]
synonym: "hAPLP2" EXACT PRO-short-label [PRO:DNx]
synonym: "APPH (human)" EXACT [UniProtKB:Q06481]
synonym: "CDEBP (human)" EXACT [UniProtKB:Q06481]
synonym: "APLP-2 (human)" EXACT [UniProtKB:Q06481]
synonym: "amyloid-like protein 2 (human)" EXACT [UniProtKB:Q06481]
synonym: "amyloid protein homolog (human)" EXACT [UniProtKB:Q06481]
synonym: "CDEI box-binding protein (human)" EXACT [UniProtKB:Q06481]
synonym: "sperm membrane protein YWK-II (human)" EXACT [UniProtKB:Q06481]
synonym: "amyloid beta (A4) precursor-like protein 2 (human)" EXACT [UniProtKB:Q06481]
xref: UniProtKB:Q06481
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000004137 ! amyloid beta precursor like protein 2
relationship: has_gene_template HGNC:598 ! APLP2 (human)

[Term]
id: PR:000056889
name: amyloid beta precursor like protein 2 O-glycosylated 1 (human)
def: "An amyloid beta precursor like protein 2 (human) that has been O-glycosylated at the residue equivalent to Thr-367 of the amino acid sequence represented by UniProtKB:Q06481-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q06481-1, Thr-367, MOD:00005~GNO:G43417UB." [GlyGen:Q06481-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hAPLP2/OGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q06481-1, Thr-367, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q06481 ! amyloid beta precursor like protein 2 (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000004137
name: amyloid beta precursor like protein 2
def: "An amyloid beta precursor like protein that is a translation product of the human APLP2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "APPH" EXACT []
synonym: "APLP2" EXACT PRO-short-label [PRO:DNx]
synonym: "APPL2" RELATED Gene-based []
synonym: "CDEBP" EXACT []
synonym: "APLP-2" EXACT []
synonym: "amyloid-like protein 2" EXACT []
synonym: "amyloid protein homolog" BROAD [PRO:DAN]
synonym: "CDEI box-binding protein" EXACT []
synonym: "sperm membrane protein YWK-II" EXACT []
synonym: "amyloid beta (A4) precursor-like protein 2" EXACT []
is_a: PR:000050011 ! amyloid beta precursor like protein

[Term]
id: PR:Q06481-1
name: amyloid beta precursor like protein 2 isoform h1 (human)
def: "An amyloid beta precursor like protein 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q06481-1." [PRO:DNx, UniProtKB:Q06481]
comment: Category=organism-sequence.
synonym: "hAPLP2/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q06481-1
is_a: PR:Q06481 ! amyloid beta precursor like protein 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000056890
name: amyloid beta precursor like protein 2 O-glycosylated 2 (human)
def: "An amyloid beta precursor like protein 2 (human) that has been O-glycosylated at the residue equivalent to Thr-371 of the amino acid sequence represented by UniProtKB:Q06481-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q06481-1, Thr-371, MOD:00005~GNO:G43417UB." [GlyGen:Q06481-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hAPLP2/OGlyco:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q06481-1, Thr-371, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q06481 ! amyloid beta precursor like protein 2 (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000056891
name: amyloid beta precursor like protein 2 O-glycosylated 3 (human)
def: "An amyloid beta precursor like protein 2 (human) that has been O-glycosylated at the residue equivalent to Thr-43 of the amino acid sequence represented by UniProtKB:Q06481-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q06481-1, Thr-43, MOD:00005~GNO:G43417UB." [GlyGen:Q06481-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hAPLP2/OGlyco:3" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q06481-1, Thr-43, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q06481 ! amyloid beta precursor like protein 2 (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q06481-2
name: amyloid beta precursor like protein 2 isoform 2 (human)
def: "An amyloid beta precursor like protein 2 isoform 2 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hAPLP2/iso:2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q06481-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000040306 ! amyloid beta precursor like protein 2 isoform 2

[Term]
id: PR:Q06481-3
name: amyloid beta precursor like protein 2 isoform h3 (human)
def: "An amyloid beta precursor like protein 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q06481-3." [PRO:DNx, UniProtKB:Q06481]
comment: Category=organism-sequence.
synonym: "hAPLP2/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q06481-3
is_a: PR:Q06481 ! amyloid beta precursor like protein 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q06481-4
name: amyloid beta precursor like protein 2 isoform 4 (human)
def: "An amyloid beta precursor like protein 2 isoform 4 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hAPLP2/iso:4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q06481-4
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000040307 ! amyloid beta precursor like protein 2 isoform 4

[Term]
id: PR:Q06481-5
name: amyloid beta precursor like protein 2 isoform h5 (human)
def: "An amyloid beta precursor like protein 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q06481-5." [PRO:DNx, UniProtKB:Q06481]
comment: Category=organism-sequence.
synonym: "hAPLP2/iso:h5" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q06481-5
is_a: PR:Q06481 ! amyloid beta precursor like protein 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q06481-6
name: amyloid beta precursor like protein 2 isoform h6 (human)
def: "An amyloid beta precursor like protein 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q06481-6." [PRO:DNx, UniProtKB:Q06481]
comment: Category=organism-sequence.
synonym: "hAPLP2/iso:h6" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q06481-6
is_a: PR:Q06481 ! amyloid beta precursor like protein 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens