[Term]
id: PR:000004134
name: aprataxin and PNK-like factor
def: "A protein that is a translation product of the human APLF gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "APLF" EXACT PRO-short-label [PRO:DNx]
synonym: "PALF" RELATED Gene-based []
synonym: "XIP1" RELATED Gene-based []
synonym: "C2orf13" RELATED Gene-based []
synonym: "XRCC1-interacting protein 1" EXACT []
synonym: "apurinic-apyrimidinic endonuclease APLF" EXACT []
synonym: "PNK and APTX-like FHA domain-containing protein" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q8IW19
name: aprataxin and PNK-like factor (human)
def: "An aprataxin and PNK-like factor that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q8IW19]
comment: Category=organism-gene.
synonym: "APLF" RELATED Gene-based [UniProtKB:Q8IW19]
synonym: "PALF" RELATED Gene-based [UniProtKB:Q8IW19]
synonym: "XIP1" RELATED Gene-based [UniProtKB:Q8IW19]
synonym: "hAPLF" EXACT PRO-short-label [PRO:DNx]
synonym: "C2orf13" RELATED Gene-based [UniProtKB:Q8IW19]
synonym: "XRCC1-interacting protein 1 (human)" EXACT [UniProtKB:Q8IW19]
synonym: "apurinic-apyrimidinic endonuclease APLF (human)" EXACT [UniProtKB:Q8IW19]
synonym: "PNK and APTX-like FHA domain-containing protein (human)" EXACT [UniProtKB:Q8IW19]
xref: UniProtKB:Q8IW19
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000004134 ! aprataxin and PNK-like factor
relationship: has_gene_template HGNC:28724 ! APLF (human)

[Term]
id: PR:000045987
name: aprataxin and PNK-like factor phosphorylated 1 (human)
def: "An aprataxin and PNK-like factor (human) that has been phosphorylated at Ser-116. UniProtKB:Q8IW19, Ser-116, MOD:00046." [PMID:17507382, iPTMnet:Q8IW19]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:17507382). Status=unreviewed.
synonym: "hAPLF/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q8IW19, Ser-116, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:Q8IW19 ! aprataxin and PNK-like factor (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens