[Term]
id: PR:Q8C7N7-1
name: gamma-secretase subunit APH-1B isoform 1 (mouse)
def: "A gamma-secretase subunit APH-1B isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mAPH1B/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8C7N7-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000042189 ! gamma-secretase subunit APH-1B isoform 1

[Term]
id: PR:Q8JHE9
name: gamma-secretase subunit Aph-1b (zebrafish)
def: "A gamma-secretase subunit APH-1B that is encoded in the genome of zebrafish." [OMA:Q8JHE9, PRO:DNx]
comment: Category=organism-gene.
synonym: "psfl" RELATED Gene-based [UniProtKB:Q8JHE9]
synonym: "aph1b" RELATED Gene-based [UniProtKB:Q8JHE9]
synonym: "z-APH1B" EXACT PRO-short-label [PRO:DNx]
synonym: "anterior-pharynx-defective protein 1b (zebrafish)" EXACT [UniProtKB:Q8JHE9]
xref: UniProtKB:Q8JHE9
intersection_of: only_in_taxon NCBITaxon:7955 ! Danio rerio
intersection_of: PR:000004130 ! gamma-secretase subunit APH-1B
relationship: has_gene_template ZFIN:ZDB-GENE-031118-31 ! aph1b (zebrafish)

[Term]
id: PR:000042189
name: gamma-secretase subunit APH-1B isoform 1
def: "A gamma-secretase subunit APH-1B that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8WW43-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "APH1B/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000004130 ! gamma-secretase subunit APH-1B

[Term]
id: PR:000004130
name: gamma-secretase subunit APH-1B
def: "A protein that is a translation product of the human APH1B gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene. Requested by=Alzforum.
synonym: "PSFL" RELATED Gene-based []
synonym: "APH1B" EXACT PRO-short-label [PRO:DNx]
synonym: "APH-1b" EXACT []
synonym: "Aph-1beta" EXACT []
synonym: "UNQ688/PRO1328" RELATED Gene-based []
synonym: "presenilin-stabilization factor-like" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q8WW43-1
name: gamma-secretase subunit APH-1B isoform 1 (human)
def: "A gamma-secretase subunit APH-1B isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hAPH1B/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8WW43-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000042189 ! gamma-secretase subunit APH-1B isoform 1

[Term]
id: PR:Q55FS3
name: gamma-secretase subunit Aph-1 (Dictyostelium discoideum)
def: "A gamma-secretase subunit APH-1B that is encoded in the genome of Dictyostelium discoideum." [OMA:Q55FS3, PRO:DNx]
comment: Category=organism-gene.
synonym: "aph1" RELATED Gene-based [UniProtKB:Q55FS3]
synonym: "Dicty-APH1B" EXACT PRO-short-label [PRO:DNx]
synonym: "DDB_G0267976" RELATED Gene-based [UniProtKB:Q55FS3]
xref: UniProtKB:Q55FS3
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000004130 ! gamma-secretase subunit APH-1B
relationship: has_gene_template dictyBase:DDB_G0267976 ! aph1 (Dictyostelium discoideum)

[Term]
id: PR:Q8WW43-2
name: gamma-secretase subunit APH-1B isoform h2 (human)
def: "A gamma-secretase subunit APH-1B (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8WW43-2." [PRO:DNx, UniProtKB:Q8WW43]
comment: Category=organism-sequence.
synonym: "hAPH1B/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8WW43-2
is_a: PR:Q8WW43 ! gamma-secretase subunit APH-1B (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q8WW43
name: gamma-secretase subunit APH-1B (human)
def: "A gamma-secretase subunit APH-1B that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q8WW43]
comment: Category=organism-gene.
synonym: "PSFL" RELATED Gene-based [UniProtKB:Q8WW43]
synonym: "APH1B" RELATED Gene-based [UniProtKB:Q8WW43]
synonym: "hAPH1B" EXACT PRO-short-label [PRO:DNx]
synonym: "APH-1b (human)" EXACT [UniProtKB:Q8WW43]
synonym: "UNQ688/PRO1328" RELATED Gene-based [UniProtKB:Q8WW43]
synonym: "Aph-1beta (human)" EXACT [UniProtKB:Q8WW43]
synonym: "presenilin-stabilization factor-like (human)" EXACT [UniProtKB:Q8WW43]
xref: UniProtKB:Q8WW43
xref: Reactome:R-HSA-157340 "PR:Q8WW43 located_in GO:0005886"
xref: Reactome:R-HSA-9010060 "PR:Q8WW43 located_in GO:0010008"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000004130 ! gamma-secretase subunit APH-1B
relationship: has_gene_template HGNC:24080 ! APH1B (human)