[Term]
id: PR:000004127
name: DNA-(apurinic or apyrimidinic site) endonuclease
def: "A protein that is a translation product of the human APEX1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "APE" RELATED Gene-based []
synonym: "APX" RELATED Gene-based []
synonym: "APE1" RELATED Gene-based []
synonym: "APEN" EXACT []
synonym: "APEX" RELATED Gene-based []
synonym: "HAP1" RELATED Gene-based []
synonym: "REF1" RELATED Gene-based []
synonym: "APEX1" EXACT PRO-short-label [PRO:DNx]
synonym: "REF-1" EXACT []
synonym: "APEX nuclease" EXACT []
synonym: "protein REF-1" EXACT []
synonym: "redox factor-1" EXACT []
synonym: "AP endonuclease 1" EXACT []
synonym: "apurinic-apyrimidinic endonuclease 1" EXACT []
synonym: "DNA-(apurinic or apyrimidinic site) lyase" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:P43138
name: DNA-(apurinic or apyrimidinic site) endonuclease (rat)
def: "A DNA-(apurinic or apyrimidinic site) endonuclease that is encoded in the genome of rat." [OMA:P43138, PANTHER:PTHR22748:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "Ape" RELATED Gene-based [UniProtKB:P43138]
synonym: "Apex" RELATED Gene-based [UniProtKB:P43138]
synonym: "Ref1" RELATED Gene-based [UniProtKB:P43138]
synonym: "Apex1" RELATED Gene-based [UniProtKB:P43138]
synonym: "rAPEX1" EXACT PRO-short-label [PRO:DNx]
synonym: "APEN (rat)" EXACT [UniProtKB:P43138]
synonym: "REF-1 (rat)" EXACT [UniProtKB:P43138]
synonym: "APEX nuclease (rat)" EXACT [UniProtKB:P43138]
synonym: "redox factor-1 (rat)" EXACT [UniProtKB:P43138]
synonym: "AP endonuclease 1 (rat)" EXACT [UniProtKB:P43138]
synonym: "apurinic-apyrimidinic endonuclease 1 (rat)" EXACT [UniProtKB:P43138]
xref: UniProtKB:P43138
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000004127 ! DNA-(apurinic or apyrimidinic site) endonuclease
relationship: has_gene_template RGD:2126 ! Apex1 (rat)

[Term]
id: PR:P43138-1
name: DNA-(apurinic or apyrimidinic site) endonuclease isoform 1 (rat)
def: "A DNA-(apurinic or apyrimidinic site) endonuclease isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rAPEX1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P43138-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000039197 ! DNA-(apurinic or apyrimidinic site) endonuclease isoform 1