[Term]
id: PR:000046326
name: alkaline phosphatase, placental type, signal peptide removed form (human)
def: "An alkaline phosphatase, placental type (human) that has had the signal peptide removed. UniProtKB:P05187, 23-535." [PRO:DNx, Reactome:R-HSA-8847823]
comment: Category=organism-modification.
synonym: "hALPP/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P05187, 23-535" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-8847823 "PR:000046326 located_in GO:0030133"
intersection_of: PR:P05187 ! alkaline phosphatase, placental type (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000003969
name: alkaline phosphatase, placental type
def: "A protein that is a translation product of the human ALPP gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "ALPP" EXACT PRO-short-label [PRO:DNx]
synonym: "PLAP" RELATED Gene-based []
synonym: "PLAP-1" EXACT []
synonym: "placental alkaline phosphatase 1" EXACT []
synonym: "alkaline phosphatase Regan isozyme" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:P05187
name: alkaline phosphatase, placental type (human)
def: "An alkaline phosphatase, placental type that is encoded in the genome of human." [PRO:DNx, UniProtKB:P05187]
comment: Category=organism-gene.
synonym: "ALPP" RELATED Gene-based [UniProtKB:P05187]
synonym: "PLAP" RELATED Gene-based [UniProtKB:P05187]
synonym: "hALPP" EXACT PRO-short-label [PRO:DNx]
synonym: "PLAP-1 (human)" BROAD [UniProtKB:P05187]
synonym: "placental alkaline phosphatase 1 (human)" EXACT [UniProtKB:P05187]
synonym: "alkaline phosphatase Regan isozyme (human)" EXACT [UniProtKB:P05187]
xref: UniProtKB:P05187
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003969 ! alkaline phosphatase, placental type
relationship: has_gene_template HGNC:439 ! ALPP (human)

[Term]
id: PR:000050345
name: alkaline phosphatase, placental type, mature form (human)
def: "An alkaline phosphatase, placental type (human) that has had the signal peptide and propeptide removed." [PRO:DAN]
comment: Category=organism-modification. Requested by=MAxO.
synonym: "hALPP/mature" EXACT PRO-short-label [PRO:DAN]
intersection_of: PR:P05187 ! alkaline phosphatase, placental type (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
intersection_of: lacks_part SO:0001062 ! propeptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens