[Term]
id: PR:P50578
name: aldo-keto reductase family 1 member A1 (pig)
def: "An aldo-keto reductase family 1 member A1 that is encoded in the genome of pig." [OMA:P50578, PRO:DNx]
comment: Category=organism-gene. Requested by=PubChem.
synonym: "ALR" RELATED Gene-based [UniProtKB:P50578]
synonym: "ALR1" RELATED Gene-based [UniProtKB:P50578]
synonym: "AKR1A1" RELATED Gene-based [UniProtKB:P50578]
synonym: "pig-AKR1A1" EXACT PRO-short-label [PRO:DNx]
synonym: "aldehyde reductase (pig)" BROAD [PRO:DAN, UniProtKB:P50578]
synonym: "glucuronate reductase (pig)" EXACT [UniProtKB:P50578]
synonym: "glucuronolactone reductase (pig)" EXACT [UniProtKB:P50578]
synonym: "alcohol dehydrogenase [NADP(+)] (pig)" EXACT [UniProtKB:P50578]
xref: UniProtKB:P50578
intersection_of: only_in_taxon NCBITaxon:9823 ! Sus scrofa
intersection_of: PR:000003900 ! aldo-keto reductase family 1 member A1
relationship: has_gene_template NCBIGene:396924 ! AKR1A1 (pig)

[Term]
id: PR:000038906
name: aldo-keto reductase family 1 member A1 isoform 1
def: "An aldo-keto reductase family 1 member A1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P14550-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "AKR1A1/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000003900 ! aldo-keto reductase family 1 member A1

[Term]
id: PR:000046292
name: aldo-keto reductase family 1 member A1, initiator methionine removed form (human)
def: "An aldo-keto reductase family 1 member A1 (human) that has had the initiator methionine removed. UniProtKB:P14550, 2-325." [PRO:DNx, Reactome:R-HSA-5661253]
comment: Category=organism-modification.
synonym: "PRO_0000124617" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hAKR1A1/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P14550, 2-325" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5661253 "PR:000046292 located_in GO:0005829"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:P14550 ! aldo-keto reductase family 1 member A1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P14550-1
name: aldo-keto reductase family 1 member A1 isoform 1 (human)
def: "An aldo-keto reductase family 1 member A1 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hAKR1A1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P14550-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000038906 ! aldo-keto reductase family 1 member A1 isoform 1

[Term]
id: PR:Q9JII6
name: aldo-keto reductase family 1 member A1 (mouse)
def: "An aldo-keto reductase family 1 member A1 that is encoded in the genome of mouse." [OMA:Q9JII6, PRO:DNx]
comment: Category=organism-gene.
synonym: "Akr1a1" RELATED Gene-based [UniProtKB:Q9JII6]
synonym: "Akr1a4" RELATED Gene-based [UniProtKB:Q9JII6]
synonym: "mAKR1A1" EXACT PRO-short-label [PRO:DNx]
synonym: "aldehyde reductase (mouse)" BROAD [UniProtKB:Q9JII6]
synonym: "glucuronate reductase (mouse)" EXACT [UniProtKB:Q9JII6]
synonym: "glucuronolactone reductase (mouse)" EXACT [UniProtKB:Q9JII6]
synonym: "alcohol dehydrogenase [NADP(+)] (mouse)" EXACT [UniProtKB:Q9JII6]
xref: UniProtKB:Q9JII6
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000003900 ! aldo-keto reductase family 1 member A1
relationship: has_gene_template MGI:1929955 ! Akr1a1 (mouse)

[Term]
id: PR:000003900
name: aldo-keto reductase family 1 member A1
def: "A protein that is a translation product of the human AKR1A1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "ALR" RELATED Gene-based []
synonym: "ALDR1" RELATED Gene-based []
synonym: "AKR1A1" EXACT PRO-short-label [PRO:DNx]
synonym: "Akr1a4" RELATED Gene-based []
synonym: "aldehyde reductase" RELATED []
synonym: "glucuronate reductase" EXACT []
synonym: "glucuronolactone reductase" EXACT []
synonym: "alcohol dehydrogenase [NADP(+)]" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q5ZK84
name: aldo-keto reductase family 1 member A1 (chicken)
def: "An aldo-keto reductase family 1 member A1 that is encoded in the genome of chicken." [OMA:Q5ZK84, PRO:DNx]
comment: Category=organism-gene.
synonym: "AKR1A1" RELATED Gene-based [UniProtKB:Q5ZK84]
synonym: "RCJMB04_12g8" RELATED Gene-based [UniProtKB:Q5ZK84]
synonym: "chick-AKR1A1" EXACT PRO-short-label [PRO:DNx]
synonym: "aldehyde reductase (chicken)" EXACT [UniProtKB:Q5ZK84]
synonym: "alcohol dehydrogenase [NADP(+)] (chicken)" EXACT [UniProtKB:Q5ZK84]
xref: UniProtKB:Q5ZK84
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000003900 ! aldo-keto reductase family 1 member A1
relationship: has_gene_template NCBIGene:424599 ! AKR1A1 (chicken)

[Term]
id: PR:P51635
name: aldo-keto reductase family 1 member A1 (rat)
def: "An aldo-keto reductase family 1 member A1 that is encoded in the genome of rat." [OMA:P51635, PRO:DNx]
comment: Category=organism-gene.
synonym: "Alr" RELATED Gene-based [UniProtKB:P51635]
synonym: "Akr1a1" RELATED Gene-based [UniProtKB:P51635]
synonym: "rAKR1A1" EXACT PRO-short-label [PRO:DNx]
synonym: "aldehyde reductase (rat)" RELATED [UniProtKB:P51635]
synonym: "3-DG-reducing enzyme (rat)" EXACT [UniProtKB:P51635]
synonym: "glucuronate reductase (rat)" EXACT [UniProtKB:P51635]
synonym: "glucuronolactone reductase (rat)" EXACT [UniProtKB:P51635]
synonym: "alcohol dehydrogenase [NADP(+)] (rat)" EXACT [UniProtKB:P51635]
xref: UniProtKB:P51635
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000003900 ! aldo-keto reductase family 1 member A1
relationship: has_gene_template RGD:68346 ! Akr1a1 (rat)

[Term]
id: PR:Q568L5
name: aldo-keto reductase family 1 member A1-B (zebrafish)
def: "An aldo-keto reductase family 1 member A1 that is encoded in the genome of zebrafish." [OMA:Q568L5, PRO:DNx]
comment: Category=organism-gene.
synonym: "akr1a1b" RELATED Gene-based [UniProtKB:Q568L5]
synonym: "z-AKR1A1" EXACT PRO-short-label [PRO:DNx]
synonym: "zgc:110225" RELATED Gene-based [UniProtKB:Q568L5]
synonym: "aldehyde reductase-B (zebrafish)" EXACT [UniProtKB:Q568L5]
synonym: "alcohol dehydrogenase [NADP(+)] B (zebrafish)" EXACT [UniProtKB:Q568L5]
xref: UniProtKB:Q568L5
intersection_of: only_in_taxon NCBITaxon:7955 ! Danio rerio
intersection_of: PR:000003900 ! aldo-keto reductase family 1 member A1
relationship: has_gene_template ZFIN:ZDB-GENE-050417-118 ! akr1a1b (zebrafish)

[Term]
id: PR:Q9JII6-1
name: aldo-keto reductase family 1 member A1 isoform 1 (mouse)
def: "An aldo-keto reductase family 1 member A1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mAKR1A1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9JII6-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000038906 ! aldo-keto reductase family 1 member A1 isoform 1

[Term]
id: PR:P51635-1
name: aldo-keto reductase family 1 member A1 isoform 1 (rat)
def: "An aldo-keto reductase family 1 member A1 isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rAKR1A1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P51635-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000038906 ! aldo-keto reductase family 1 member A1 isoform 1

[Term]
id: PR:P14550
name: aldo-keto reductase family 1 member A1 (human)
def: "An aldo-keto reductase family 1 member A1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P14550]
comment: Category=organism-gene.
synonym: "ALR" RELATED Gene-based [UniProtKB:P14550]
synonym: "ALDR1" RELATED Gene-based [UniProtKB:P14550]
synonym: "AKR1A1" RELATED Gene-based [UniProtKB:P14550]
synonym: "hAKR1A1" EXACT PRO-short-label [PRO:DNx]
synonym: "aldehyde reductase (human)" BROAD [UniProtKB:P14550]
synonym: "glucuronate reductase (human)" EXACT [UniProtKB:P14550]
synonym: "glucuronolactone reductase (human)" EXACT [UniProtKB:P14550]
synonym: "alcohol dehydrogenase [NADP(+)] (human)" EXACT [UniProtKB:P14550]
xref: UniProtKB:P14550
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003900 ! aldo-keto reductase family 1 member A1
relationship: has_gene_template HGNC:380 ! AKR1A1 (human)

[Term]
id: PR:000018942
name: aldo-keto reductase family 1 member A1, initiator methionine removed form
def: "An aldo-keto reductase family 1 member A1 that has had the initiator methionine removed." [PRO:DNx]
comment: Category=modification.
synonym: "AKR1A1/InitMet-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000003900 ! aldo-keto reductase family 1 member A1
intersection_of: lacks_part PR:000021937 ! initiator methionine