[Term]
id: PR:000003828
name: advanced glycosylation end product-specific receptor
def: "A protein that is a translation product of the human AGER gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "AGER" EXACT PRO-short-label [PRO:DNx]
synonym: "RAGE" RELATED Gene-based []
synonym: "receptor for advanced glycosylation end products" EXACT []
xref: IUPHARobj:2843
is_a: PR:000000001 ! protein

[Term]
id: PR:Q15109-9
name: advanced glycosylation end product-specific receptor isoform h9 (human)
def: "An advanced glycosylation end product-specific receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15109-9." [PRO:DNx, UniProtKB:Q15109]
comment: Category=organism-sequence.
synonym: "hAGER/iso:h9" EXACT PRO-short-label [PRO:DNx]
synonym: "advanced glycosylation end product-specific receptor isoform del exon8-9 (human)" EXACT [UniProtKB:Q15109]
xref: UniProtKB:Q15109-9
is_a: PR:Q15109 ! advanced glycosylation end product-specific receptor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045359
name: secreted RAGE (human)
def: "An advanced glycosylation end product-specific receptor (human) that consists of the ectodomain region of the protein which can be a product of a splice form or a proteolytic cleavage." [PMID:18355449, PRO:KRC]
comment: Category=union.
synonym: "sRAGE (human)" NARROW [PRO:DAN]
synonym: "hAGER/secreted" EXACT PRO-short-label [PRO:DAN]
synonym: "RAGE ectodomain (human)" RELATED []
is_a: PR:Q15109 ! advanced glycosylation end product-specific receptor (human)
union_of: PR:000045356 ! sRAGE proteolytic cleavage product (human)
union_of: PR:Q15109-3 ! advanced glycosylation end product-specific receptor isoform h3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000046282
name: advanced glycosylation end product-specific receptor, signal peptide removed form (human)
def: "An advanced glycosylation end product-specific receptor (human) that has had the signal peptide removed. UniProtKB:Q15109, 23-404." [PRO:DNx, Reactome:R-HSA-197639]
comment: Category=organism-modification.
synonym: "hAGER/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000014923" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:Q15109, 23-404" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-197639 "PR:000046282 located_in GO:0005886"
intersection_of: PR:Q15109 ! advanced glycosylation end product-specific receptor (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q15109-5
name: advanced glycosylation end product-specific receptor isoform h5 (human)
def: "An advanced glycosylation end product-specific receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15109-5." [PRO:DNx, UniProtKB:Q15109]
comment: Category=organism-sequence.
synonym: "hAGER/iso:h5" EXACT PRO-short-label [PRO:DNx]
synonym: "advanced glycosylation end product-specific receptor isoform del exon3-7 (human)" EXACT [UniProtKB:Q15109]
xref: UniProtKB:Q15109-5
is_a: PR:Q15109 ! advanced glycosylation end product-specific receptor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045356
name: sRAGE proteolytic cleavage product (human)
def: "An sRAGE proteolytic cleavage product that is produced in human." [PMID:18355449, PRO:KRC]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:18355449).
synonym: "hAGER/Clv:ecto" EXACT PRO-short-label [PRO:DAN]
synonym: "RAGE ectodomain (human)" RELATED []
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000045354 ! sRAGE proteolytic cleavage product

[Term]
id: PR:Q15109-7
name: advanced glycosylation end product-specific receptor isoform h7 (human)
def: "An advanced glycosylation end product-specific receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15109-7." [PMID:18089847, PRO:CNA, UniProtKB:Q15109]
comment: Category=organism-sequence. Evidence=(ECO:0000006, based on PMID:18089847).
synonym: "hAGER/iso:h7" EXACT PRO-short-label [PRO:DNx]
synonym: "RAGE_v4 (human)" EXACT [PMID:18089847]
synonym: "advanced glycosylation end product-specific receptor isoform del exon3 (human)" EXACT [UniProtKB:Q15109]
xref: UniProtKB:Q15109-7
is_a: PR:Q15109 ! advanced glycosylation end product-specific receptor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q15109-6
name: advanced glycosylation end product-specific receptor isoform h6 (human)
def: "An advanced glycosylation end product-specific receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15109-6." [PMID:18089847, PRO:CNA, UniProtKB:Q15109]
comment: Category=organism-sequence. Evidence=(ECO:0000006, based on PMID:18089847).
synonym: "hAGER/iso:h6" EXACT PRO-short-label [PRO:DNx]
synonym: "RAGE_v5 (human)" EXACT [PMID:18089847]
xref: UniProtKB:Q15109-6
is_a: PR:Q15109 ! advanced glycosylation end product-specific receptor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045353
name: RICD (human)
def: "A RICD that is produced in human." [PMID:18355449, PRO:KRC]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:18355449).
synonym: "hAGER/Clv:intracellular" EXACT PRO-short-label [PRO:DAN]
synonym: "RAGE intracellular domain (human)" EXACT []
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000045350 ! RICD

[Term]
id: PR:Q15109-3
name: advanced glycosylation end product-specific receptor isoform h3 (human)
def: "An advanced glycosylation end product-specific receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15109-3." [PMID:18089847, PRO:CNA, UniProtKB:Q15109]
comment: Category=organism-sequence. Evidence=(ECO:0000006, based on PMID:18089847). Note: At least two splice variants give rise to this protein GenBank:AY755628 and GenBank:AY755620.
synonym: "hAGER/iso:h3" EXACT PRO-short-label [PRO:DNx]
synonym: "sRAGE (human)" EXACT []
synonym: "esRAGE (human)" EXACT []
synonym: "sRAGE2 (human)" EXACT []
synonym: "RAGE_v1 (human)" RELATED [PMID:18089847]
synonym: "RAGE_v10 (human)" RELATED [PMID:18089847]
synonym: "C-truncated RAGE (human)" EXACT []
xref: UniProtKB:Q15109-3
is_a: PR:Q15109 ! advanced glycosylation end product-specific receptor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q15109-2
name: advanced glycosylation end product-specific receptor isoform h2 (human)
def: "An advanced glycosylation end product-specific receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15109-2." [PRO:DNx, UniProtKB:Q15109]
comment: Category=organism-sequence. Evidence=(ECO:0000006, based on PMID:18089847).
synonym: "hRAGEsec" EXACT [PMID:18089847]
synonym: "hAGER/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "RAGE_v16 (human)" EXACT [PMID:18089847]
synonym: "advanced glycosylation end product-specific receptor isoform RAGESEC (human)" EXACT [UniProtKB:Q15109]
xref: UniProtKB:Q15109-2
is_a: PR:Q15109 ! advanced glycosylation end product-specific receptor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q3L1R2
name: advanced glycosylation end product-specific receptor isoform h11 (human)
def: "An advanced glycosylation end product-specific receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q3L1R2." [PMID:18089847, PRO:CNA, PRO:DAN, UniProtKB:Q3L1R2]
comment: Category=organism-sequence. Evidence=(ECO:0000006, based on PMID:18089847). Note: This form is encoded by a transcript that lacks the region coding for exons 3-10.
synonym: "hAGER/iso:h11" EXACT PRO-short-label [PRO:DAN]
synonym: "RAGE_v13 (human)" EXACT [PMID:18089847]
xref: UniProtKB:Q3L1R2
is_a: PR:Q15109 ! advanced glycosylation end product-specific receptor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q15109-4
name: advanced glycosylation end product-specific receptor isoform h4 (human)
def: "An advanced glycosylation end product-specific receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15109-4." [PMID:18089847, PRO:CNA, UniProtKB:Q15109]
comment: Category=organism-sequence. Evidence=(ECO:0000006, based on PMID:18089847).
synonym: "hAGER/iso:h4" EXACT PRO-short-label [PRO:DNx]
synonym: "RAGE_v6 (human)" EXACT [PMID:18089847]
xref: UniProtKB:Q15109-4
is_a: PR:Q15109 ! advanced glycosylation end product-specific receptor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q15109-1
name: advanced glycosylation end product-specific receptor isoform h1 (human)
def: "An advanced glycosylation end product-specific receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15109-1." [PMID:18089847, PRO:CNA, UniProtKB:Q15109]
comment: Category=organism-sequence. Evidence=(ECO:0000006, based on PMID:18089847).
synonym: "RAGE (human)" RELATED []
synonym: "hAGER/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q15109-1
is_a: PR:Q15109 ! advanced glycosylation end product-specific receptor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q15109-10
name: advanced glycosylation end product-specific receptor isoform h10 (human)
def: "An advanced glycosylation end product-specific receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15109-10." [PRO:DNx, UniProtKB:Q15109]
comment: Category=organism-sequence.
synonym: "hAGER/iso:h10" EXACT PRO-short-label [PRO:DNx]
synonym: "advanced glycosylation end product-specific receptor isoform delta-ICD (human)" EXACT [UniProtKB:Q15109]
synonym: "advanced glycosylation end product-specific receptor isoform variant 20 (human)" EXACT [UniProtKB:Q15109]
xref: UniProtKB:Q15109-10
is_a: PR:Q15109 ! advanced glycosylation end product-specific receptor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q15109
name: advanced glycosylation end product-specific receptor (human)
def: "An advanced glycosylation end product-specific receptor that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q15109]
comment: Category=organism-gene.
synonym: "AGER" RELATED Gene-based [UniProtKB:Q15109]
synonym: "RAGE" RELATED Gene-based [UniProtKB:Q15109]
synonym: "hAGER" EXACT PRO-short-label [PRO:DNx]
synonym: "receptor for advanced glycosylation end products (human)" EXACT [UniProtKB:Q15109]
xref: UniProtKB:Q15109
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003828 ! advanced glycosylation end product-specific receptor
relationship: has_gene_template HGNC:320 ! AGER (human)

[Term]
id: PR:Q15109-8
name: advanced glycosylation end product-specific receptor isoform h8 (human)
def: "An advanced glycosylation end product-specific receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15109-8." [PRO:DNx, UniProtKB:Q15109]
comment: Category=organism-sequence.
synonym: "hAGER/iso:h8" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q15109-8
is_a: PR:Q15109 ! advanced glycosylation end product-specific receptor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens