[Term]
id: PR:P10989
name: actin (Schizosaccharomyces pombe 972h-)
def: "An actin, cytoplasmic 2 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:P10989, PRO:DNx]
comment: Category=organism-gene.
synonym: "act1" RELATED Gene-based [UniProtKB:P10989]
synonym: "cps8" RELATED Gene-based [UniProtKB:P10989]
synonym: "pi012" RELATED Gene-based [UniProtKB:P10989]
synonym: "SPBC32H8.12c" RELATED Gene-based [UniProtKB:P10989]
synonym: "Spom972h-ACTG1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P10989
intersection_of: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h-
intersection_of: PR:000003680 ! actin, cytoplasmic 2
relationship: has_gene_template PomBase:SPBC32H8.12c ! act1 (Schizosaccharomyces pombe)

[Term]
id: PR:000003680
name: actin, cytoplasmic 2
def: "A protein that is a translation product of the human ACTG1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "ACTB" RELATED []
synonym: "ACTG" RELATED Gene-based []
synonym: "ACTG1" EXACT PRO-short-label [PRO:DNx]
synonym: "gamma-actin" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:P63260-1
name: actin, cytoplasmic 2 isoform 1 (mouse)
def: "An actin, cytoplasmic 2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mACTG1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P63260-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000040085 ! actin, cytoplasmic 2 isoform 1

[Term]
id: PR:000040085
name: actin, cytoplasmic 2 isoform 1
def: "An actin, cytoplasmic 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P63261-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "ACTG1/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000003680 ! actin, cytoplasmic 2

[Term]
id: PR:P63260
name: actin, cytoplasmic 2 (mouse)
def: "An actin, cytoplasmic 2 that is encoded in the genome of mouse." [OMA:P63260, PRO:DNx]
comment: Category=organism-gene.
synonym: "Actg" RELATED Gene-based [UniProtKB:P63260]
synonym: "Actg1" RELATED Gene-based [UniProtKB:P63260]
synonym: "mACTG1" EXACT PRO-short-label [PRO:DNx]
synonym: "gamma-actin (mouse)" EXACT [UniProtKB:P63260]
xref: UniProtKB:P63260
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000003680 ! actin, cytoplasmic 2
relationship: has_gene_template MGI:87906 ! Actg1 (mouse)

[Term]
id: PR:P63261
name: actin, cytoplasmic 2 (human)
def: "An actin, cytoplasmic 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P63261]
comment: Category=organism-gene.
synonym: "ACTG" RELATED Gene-based [UniProtKB:P63261]
synonym: "ACTG1" RELATED Gene-based [UniProtKB:P63261]
synonym: "hACTG1" EXACT PRO-short-label [PRO:DNx]
synonym: "gamma-actin (human)" EXACT [UniProtKB:P63261]
xref: Reactome:R-HSA-201858 "PR:P63261 located_in GO:0005829"
xref: Reactome:R-HSA-196044 "PR:P63261 located_in GO:0005886"
xref: Reactome:R-HSA-196169 "PR:P63261 located_in GO:0005765"
xref: UniProtKB:P63261
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003680 ! actin, cytoplasmic 2
relationship: has_gene_template HGNC:144 ! ACTG1 (human)

[Term]
id: PR:P60010
name: actin (yeast)
def: "An actin, cytoplasmic 2 that is encoded in the genome of yeast." [OMA:P60010, PRO:DNx]
comment: Category=organism-gene.
synonym: "ABY1" RELATED Gene-based [UniProtKB:P60010]
synonym: "ACT1" RELATED Gene-based [UniProtKB:P60010]
synonym: "END7" RELATED Gene-based [UniProtKB:P60010]
synonym: "yACTG1" EXACT PRO-short-label [PRO:DNx]
synonym: "YFL039C" RELATED Gene-based [UniProtKB:P60010]
xref: UniProtKB:P60010
intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C
intersection_of: PR:000003680 ! actin, cytoplasmic 2
relationship: has_gene_template SGD:S000001855 ! ACT1 (yeast)

[Term]
id: PR:000018887
name: actin, cytoplasmic 2 proteolytic cleavage product
def: "An actin, cytoplasmic 2 that has been processed by proteolytic cleavage." [PRO:DNx]
comment: Category=modification.
synonym: "ACTG1/ClvPrd" EXACT PRO-short-label [PRO:DNx]
intersection_of: output_of GO:0016485 ! protein processing
intersection_of: PR:000003680 ! actin, cytoplasmic 2

[Term]
id: PR:000018886
name: actin, cytoplasmic 2, initiator methionine removed form
def: "An actin, cytoplasmic 2 that has had the initiator methionine removed." [PRO:DNx]
comment: Category=modification.
synonym: "ACTG1/InitMet-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000003680 ! actin, cytoplasmic 2
intersection_of: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:P63261-1
name: actin, cytoplasmic 2 isoform 1 (human)
def: "An actin, cytoplasmic 2 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hACTG1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P63261-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000040085 ! actin, cytoplasmic 2 isoform 1

[Term]
id: PR:P63259
name: actin, cytoplasmic 2 (rat)
def: "An actin, cytoplasmic 2 that is encoded in the genome of rat." [OMA:P63259, PRO:DNx]
comment: Category=organism-gene.
synonym: "Actg" RELATED Gene-based [UniProtKB:P63259]
synonym: "Actg1" RELATED Gene-based [UniProtKB:P63259]
synonym: "rACTG1" EXACT PRO-short-label [PRO:DNx]
synonym: "gamma-actin (rat)" EXACT [UniProtKB:P63259]
xref: UniProtKB:P63259
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000003680 ! actin, cytoplasmic 2
relationship: has_gene_template RGD:1304556 ! Actg1 (rat)

[Term]
id: PR:000036200
name: actin, cytoplasmic 2 acetylated 1 (human)
def: "An actin, cytoplasmic 2 (human) that is N-terminal Met acetylated. UniProtKB:P63261, Met-1, MOD:00058." [TDR:1509]
comment: Category=organism-modification. Note: Top down proteomics. Evidence=(ECO:0000006).
synonym: "hACTG1/Ac:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P63261, Met-1, MOD:00058" EXACT PRO-proteoform-std [PRO:DNx]
xref: TDR:1509
is_a: PR:P63261 ! actin, cytoplasmic 2 (human)
relationship: has_part MOD:00058 ! N-acetyl-L-methionine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens