[Term]
id: PR:000003676
name: actin, cytoplasmic 1
def: "A protein that is a translation product of the human ACTB gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "ACTB" EXACT PRO-short-label [PRO:DNx]
synonym: "beta-actin" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000036179
name: actin, cytoplasmic 1 acetylated 1 (human)
def: "An actin, cytoplasmic 1 (human) that is N-terminal Met acetylated. UniProtKB:P60709, Met-1, MOD:00058." [TDR:1964]
comment: Category=organism-modification. Note: Top down proteomics. Evidence=(ECO:0000006).
synonym: "hACTB/Ac:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P60709, Met-1, MOD:00058" EXACT PRO-proteoform-std [PRO:DNx]
xref: TDR:1964
is_a: PR:P60709 ! actin, cytoplasmic 1 (human)
relationship: has_part MOD:00058 ! N-acetyl-L-methionine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000036900
name: actin, cytoplasmic 1 phosphorylated 1 (human)
def: "An actin, cytoplasmic 1 (human) that has been phosphorylated on Tyr-91, Tyr-198, and Tyr-218. UniProtKB:P60709, Tyr-91/Tyr-198/Tyr-218, MOD:00048." [TDR:2663]
comment: Category=organism-modification.
synonym: "hACTB/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P60709, Tyr-91/Tyr-198/Tyr-218, MOD:00048" EXACT PRO-proteoform-std [PRO:DAN]
xref: TDR:2663
is_a: PR:P60709 ! actin, cytoplasmic 1 (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P60709
name: actin, cytoplasmic 1 (human)
def: "An actin, cytoplasmic 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P60709]
comment: Category=organism-gene. Requested by=PubChem.
synonym: "ACTB" RELATED Gene-based [UniProtKB:P60709]
synonym: "hACTB" EXACT PRO-short-label [PRO:DNx]
synonym: "beta-actin (human)" EXACT [UniProtKB:P60709]
xref: UniProtKB:P60709
xref: Reactome:R-HSA-201861 "PR:P60709 located_in GO:0005829"
xref: Reactome:R-HSA-196016 "PR:P60709 located_in GO:0005886"
xref: Reactome:R-HSA-196160 "PR:P60709 located_in GO:0005765"
xref: Reactome:R-HSA-390462 "PR:P60709 located_in GO:0005829"
xref: Reactome:R-HSA-3321990 "PR:P60709 located_in GO:0005654"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003676 ! actin, cytoplasmic 1
relationship: has_gene_template HGNC:132 ! ACTB (human)

[Term]
id: PR:P60709-1
name: actin, cytoplasmic 1 isoform 1 (human)
def: "An actin, cytoplasmic 1 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hACTB/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P60709-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000039894 ! actin, cytoplasmic 1 isoform 1