[Term]
id: PR:000003626
name: acetylcholinesterase
def: "A protein that is a translation product of the human ACHE gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "ACHE" EXACT PRO-short-label [PRO:DNx]
xref: IUPHARobj:2465
is_a: PR:000000001 ! protein

[Term]
id: PR:P22303
name: acetylcholinesterase (human)
def: "An acetylcholinesterase that is encoded in the genome of human." [PRO:DNx, UniProtKB:P22303]
comment: Category=organism-gene.
synonym: "ACHE" RELATED Gene-based [UniProtKB:P22303]
synonym: "hACHE" EXACT PRO-short-label [PRO:DNx]
synonym: "AChE (human)" EXACT [UniProtKB:P22303]
xref: UniProtKB:P22303
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003626 ! acetylcholinesterase
relationship: has_gene_template HGNC:108 ! ACHE (human)

[Term]
id: PR:P22303-4
name: acetylcholinesterase isoform R (human)
def: "An acetylcholinesterase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22303-4." [PRO:DNx, UniProtKB:P22303]
comment: Category=organism-sequence.
synonym: "hACHE/iso:R" EXACT PRO-short-label [PRO:DNx]
synonym: "acetylcholinesterase isoform ACHE-R (human)" EXACT [UniProtKB:P22303]
synonym: "acetylcholinesterase isoform readthrough (human)" EXACT [UniProtKB:P22303]
xref: UniProtKB:P22303-4
is_a: PR:P22303 ! acetylcholinesterase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000046239
name: acetylcholinesterase, signal peptide removed form (human)
def: "An acetylcholinesterase (human) that has had the signal peptide removed. UniProtKB:P22303, 32-614." [PRO:DNx, Reactome:R-HSA-1524050, Reactome:R-HSA-372506]
comment: Category=organism-modification.
synonym: "hACHE/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000008587" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P22303, 32-614" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-372506 "PR:000046239 located_in GO:0005576"
xref: Reactome:R-HSA-1524050 "PR:000046239 located_in GO:0005886"
intersection_of: PR:P22303 ! acetylcholinesterase (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P22303-1
name: acetylcholinesterase isoform T (human)
def: "An acetylcholinesterase isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hACHE/iso:T" EXACT PRO-short-label [PRO:DNx]
synonym: "acetylcholinesterase isoform ACHE-S (human)" EXACT [UniProtKB:P22303]
synonym: "acetylcholinesterase isoform synaptic (human)" EXACT [UniProtKB:P22303]
xref: UniProtKB:P22303-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000039067 ! acetylcholinesterase isoform 1

[Term]
id: PR:P22303-2
name: acetylcholinesterase isoform H (human)
def: "An acetylcholinesterase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22303-2." [PRO:DNx, UniProtKB:P22303]
comment: Category=organism-sequence.
synonym: "hACHE/iso:H" EXACT PRO-short-label [PRO:DNx]
synonym: "acetylcholinesterase isoform E4-E5 (human)" EXACT [UniProtKB:P22303]
synonym: "acetylcholinesterase isoform ACHE-E (human)" EXACT [UniProtKB:P22303]
synonym: "acetylcholinesterase isoform erythrocytic (human)" EXACT [UniProtKB:P22303]
xref: UniProtKB:P22303-2
is_a: PR:P22303 ! acetylcholinesterase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P22303-3
name: acetylcholinesterase isoform h4 (human)
def: "An acetylcholinesterase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22303-3." [PRO:DNx, UniProtKB:P22303]
comment: Category=organism-sequence.
synonym: "hACHE/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P22303-3
is_a: PR:P22303 ! acetylcholinesterase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens