[Term]
id: PR:Q5EGZ1
name: angiotensin-converting enzyme 2 (rat)
def: "An angiotensin-converting enzyme 2 that is encoded in the genome of rat." [OMA:Q5EGZ1, PANTHER:PTHR10514:SF10, PRO:DNx]
comment: Category=organism-gene.
synonym: "Ace2" RELATED Gene-based [UniProtKB:Q5EGZ1]
synonym: "rACE2" EXACT PRO-short-label [PRO:DNx]
synonym: "ACE-related carboxypeptidase (rat)" EXACT [UniProtKB:Q5EGZ1]
xref: UniProtKB:Q5EGZ1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000003622 ! angiotensin-converting enzyme 2
relationship: has_gene_template RGD:728890 ! Ace2 (rat)

[Term]
id: PR:Q8R0I0
name: angiotensin-converting enzyme 2 (mouse)
def: "An angiotensin-converting enzyme 2 that is encoded in the genome of mouse." [OMA:Q8R0I0, PRO:DNx]
comment: Category=organism-gene.
synonym: "Ace2" RELATED Gene-based [UniProtKB:Q8R0I0]
synonym: "mACE2" EXACT PRO-short-label [PRO:DNx]
synonym: "ACE-related carboxypeptidase (mouse)" EXACT [UniProtKB:Q8R0I0]
xref: UniProtKB:Q8R0I0
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000003622 ! angiotensin-converting enzyme 2
relationship: has_gene_template MGI:1917258 ! Ace2 (mouse)

[Term]
id: PR:000042968
name: angiotensin-converting enzyme 2 isoform 1
def: "An angiotensin-converting enzyme 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BYF1-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "ACE2/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000003622 ! angiotensin-converting enzyme 2

[Term]
id: PR:000003622
name: angiotensin-converting enzyme 2
def: "A protein that is a translation product of the human ACE2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "ACE2" EXACT PRO-short-label [PRO:DNx]
synonym: "ACEH" EXACT []
synonym: "UNQ868/PRO1885" RELATED Gene-based []
synonym: "metalloprotease MPROT15" EXACT []
synonym: "ACE-related carboxypeptidase" EXACT []
synonym: "angiotensin-converting enzyme homolog" EXACT []
xref: IUPHARobj:1614
is_a: PR:000000001 ! protein

[Term]
id: PR:Q18581-2
name: inactive angiotensin-converting enzyme-related protein isoform b (worm)
def: "An inactive angiotensin-converting enzyme-related protein (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q18581-2." [PRO:DNx, UniProtKB:Q18581]
comment: Category=organism-sequence.
synonym: "ACE2/iso:b (worm)" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q18581-2
is_a: PR:Q18581 ! inactive angiotensin-converting enzyme-related protein (worm)
relationship: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans

[Term]
id: PR:Q18581-1
name: inactive angiotensin-converting enzyme-related protein isoform a (worm)
def: "An inactive angiotensin-converting enzyme-related protein (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q18581-1." [PRO:DNx, UniProtKB:Q18581]
comment: Category=organism-sequence.
synonym: "ACE2/iso:a (worm)" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q18581-1
is_a: PR:Q18581 ! inactive angiotensin-converting enzyme-related protein (worm)
relationship: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans

[Term]
id: PR:Q8R0I0-1
name: angiotensin-converting enzyme 2 isoform 1 (mouse)
def: "An angiotensin-converting enzyme 2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mACE2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8R0I0-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000042968 ! angiotensin-converting enzyme 2 isoform 1

[Term]
id: PR:Q8R0I0-2
name: angiotensin-converting enzyme 2 isoform m2 (mouse)
def: "An angiotensin-converting enzyme 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8R0I0-2." [PRO:DNx, UniProtKB:Q8R0I0]
comment: Category=organism-sequence.
synonym: "mACE2/iso:m2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8R0I0-2
is_a: PR:Q8R0I0 ! angiotensin-converting enzyme 2 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q9BYF1-3
name: angiotensin-converting enzyme 2 isoform h2 (human)
def: "An angiotensin-converting enzyme 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BYF1-3." [PRO:DNx, UniProtKB:Q9BYF1]
comment: Category=organism-sequence.
synonym: "hACE2/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "angiotensin-converting enzyme 2 isoform dACE2 (human)" EXACT [UniProtKB:Q9BYF1]
synonym: "angiotensin-converting enzyme 2 isoform delta (human)" EXACT [UniProtKB:Q9BYF1]
synonym: "angiotensin-converting enzyme 2 isoform short (human)" EXACT [UniProtKB:Q9BYF1]
xref: UniProtKB:Q9BYF1-3
is_a: PR:Q9BYF1 ! angiotensin-converting enzyme 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9BYF1-1
name: angiotensin-converting enzyme 2 isoform 1 (human)
def: "An angiotensin-converting enzyme 2 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hACE2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9BYF1-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000042968 ! angiotensin-converting enzyme 2 isoform 1

[Term]
id: PR:Q5EGZ1-1
name: angiotensin-converting enzyme 2 isoform 1 (rat)
def: "An angiotensin-converting enzyme 2 isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rACE2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q5EGZ1-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000042968 ! angiotensin-converting enzyme 2 isoform 1

[Term]
id: PR:000018866
name: angiotensin-converting enzyme 2 proteolytic cleavage product
def: "An angiotensin-converting enzyme 2 that has been processed by proteolytic cleavage." [PRO:DNx]
comment: Category=modification.
synonym: "ACE2/ClvPrd" EXACT PRO-short-label [PRO:DNx]
intersection_of: output_of GO:0016485 ! protein processing
intersection_of: PR:000003622 ! angiotensin-converting enzyme 2

[Term]
id: PR:Q18581
name: inactive angiotensin-converting enzyme-related protein (worm)
def: "An angiotensin-converting enzyme 2 that is encoded in the genome of worm." [PRO:DNx]
comment: Category=organism-gene.
synonym: "acn-1" RELATED Gene-based [UniProtKB:Q18581]
synonym: "C42D8.5" RELATED Gene-based [UniProtKB:Q18581]
synonym: "ACE2 (worm)" EXACT PRO-short-label [PRO:DNx]
synonym: "ACE-like non-metallopeptidase protein 1 (worm)" EXACT [UniProtKB:Q18581]
xref: UniProtKB:Q18581
intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans
intersection_of: PR:000003622 ! angiotensin-converting enzyme 2
relationship: has_gene_template WormBase:WBGene00000039 ! acn-1 (worm)

[Term]
id: PR:000046238
name: angiotensin-converting enzyme 2, signal peptide removed form (human)
def: "An angiotensin-converting enzyme 2 (human) that has had the signal peptide removed. UniProtKB:Q9BYF1, 18-805." [PRO:DNx, Reactome:R-HSA-2022344]
comment: Category=organism-modification.
synonym: "hACE2/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000028570" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:Q9BYF1, 18-805" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2022344 "PR:000046238 located_in GO:0005886"
intersection_of: PR:Q9BYF1 ! angiotensin-converting enzyme 2 (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9BYF1
name: angiotensin-converting enzyme 2 (human)
def: "An angiotensin-converting enzyme 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9BYF1]
comment: Category=organism-gene.
synonym: "ACE2" RELATED Gene-based [UniProtKB:Q9BYF1]
synonym: "hACE2" EXACT PRO-short-label [PRO:DNx]
synonym: "ACEH (human)" EXACT [UniProtKB:Q9BYF1]
synonym: "UNQ868/PRO1885" RELATED Gene-based [UniProtKB:Q9BYF1]
synonym: "metalloprotease MPROT15 (human)" EXACT [UniProtKB:Q9BYF1]
synonym: "ACE-related carboxypeptidase (human)" EXACT [UniProtKB:Q9BYF1]
synonym: "angiotensin-converting enzyme homolog (human)" EXACT [UniProtKB:Q9BYF1]
synonym: "angiotensin-converting enzyme-related carboxypeptidase (human)" EXACT [UniProtKB:Q9BYF1]
xref: UniProtKB:Q9BYF1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003622 ! angiotensin-converting enzyme 2
relationship: has_gene_template HGNC:13557 ! ACE2 (human)