[Term]
id: PR:Q9NPC4
name: lactosylceramide 4-alpha-galactosyltransferase (human)
def: "A lactosylceramide 4-alpha-galactosyltransferase that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9NPC4]
comment: Category=organism-gene.
synonym: "A4GALT" RELATED Gene-based [UniProtKB:Q9NPC4]
synonym: "A14GALT" RELATED Gene-based [UniProtKB:Q9NPC4]
synonym: "A4GALT1" RELATED Gene-based [UniProtKB:Q9NPC4]
synonym: "hA4GALT" EXACT PRO-short-label [PRO:DNx]
synonym: "Gb3 synthase (human)" EXACT [UniProtKB:Q9NPC4]
synonym: "alpha4Gal-T1 (human)" EXACT [UniProtKB:Q9NPC4]
synonym: "CD77 synthase (human)" EXACT [UniProtKB:Q9NPC4]
synonym: "P1/Pk synthase (human)" EXACT [UniProtKB:Q9NPC4]
synonym: "globotriaosylceramide synthase (human)" EXACT [UniProtKB:Q9NPC4]
synonym: "alpha-1,4-galactosyltransferase (human)" EXACT [UniProtKB:Q9NPC4]
synonym: "alpha-1,4-N-acetylglucosaminyltransferase (human)" RELATED [UniProtKB:Q9NPC4]
synonym: "UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase (human)" EXACT [UniProtKB:Q9NPC4]
xref: UniProtKB:Q9NPC4
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003516 ! lactosylceramide 4-alpha-galactosyltransferase
relationship: has_gene_template HGNC:18149 ! A4GALT (human)

[Term]
id: PR:000003516
name: lactosylceramide 4-alpha-galactosyltransferase
def: "A protein that is a translation product of the human A4GALT gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene. Requested by=CL.
synonym: "A4GALT" EXACT PRO-short-label [PRO:DNx]
synonym: "A14GALT" RELATED Gene-based []
synonym: "A4GALT1" RELATED Gene-based []
synonym: "Gb3 synthase" EXACT []
synonym: "alpha4Gal-T1" EXACT []
synonym: "CD77 synthase" EXACT []
synonym: "P1/Pk synthase" EXACT []
synonym: "globotriaosylceramide synthase" EXACT []
synonym: "alpha-1,4-galactosyltransferase" EXACT []
synonym: "alpha-1,4-N-acetylglucosaminyltransferase" BROAD [PRO:DNx]
synonym: "UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000058137
name: lactosylceramide 4-alpha-galactosyltransferase O-glycosylated 1 (human)
def: "A lactosylceramide 4-alpha-galactosyltransferase (human) that has been O-glycosylated at the residue equivalent to Thr-65 of the amino acid sequence represented by UniProtKB:Q9NPC4-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q9NPC4-1, Thr-65, MOD:00005~GNO:G43417UB." [GlyGen:Q9NPC4-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hA4GALT/OGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9NPC4-1, Thr-65, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q9NPC4 ! lactosylceramide 4-alpha-galactosyltransferase (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9JI93
name: lactosylceramide 4-alpha-galactosyltransferase (rat)
def: "A lactosylceramide 4-alpha-galactosyltransferase that is encoded in the genome of rat." [OMA:Q9JI93, PRO:DNx]
comment: Category=organism-gene.
synonym: "A4galt" RELATED Gene-based [UniProtKB:Q9JI93]
synonym: "rA4GALT" EXACT PRO-short-label [PRO:DNx]
synonym: "Gb3 synthase (rat)" EXACT [UniProtKB:Q9JI93]
synonym: "alpha4Gal-T1 (rat)" EXACT [UniProtKB:Q9JI93]
synonym: "globotriaosylceramide synthase (rat)" EXACT [UniProtKB:Q9JI93]
synonym: "alpha-1,4-galactosyltransferase (rat)" EXACT [UniProtKB:Q9JI93]
synonym: "alpha-1,4-N-acetylglucosaminyltransferase (rat)" EXACT [UniProtKB:Q9JI93]
synonym: "UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase (rat)" EXACT [UniProtKB:Q9JI93]
xref: UniProtKB:Q9JI93
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000003516 ! lactosylceramide 4-alpha-galactosyltransferase
relationship: has_gene_template RGD:621583 ! A4galt (rat)

[Term]
id: PR:Q67BJ4
name: lactosylceramide 4-alpha-galactosyltransferase (mouse)
def: "A lactosylceramide 4-alpha-galactosyltransferase that is encoded in the genome of mouse." [OMA:Q67BJ4, PRO:DNx]
comment: Category=organism-gene.
synonym: "A4galt" RELATED Gene-based [UniProtKB:Q67BJ4]
synonym: "mA4GALT" EXACT PRO-short-label [PRO:DNx]
synonym: "Gb3 synthase (mouse)" EXACT [UniProtKB:Q67BJ4]
synonym: "alpha4Gal-T1 (mouse)" EXACT [UniProtKB:Q67BJ4]
synonym: "globotriaosylceramide synthase (mouse)" EXACT [UniProtKB:Q67BJ4]
synonym: "alpha-1,4-galactosyltransferase (mouse)" EXACT [UniProtKB:Q67BJ4]
synonym: "alpha-1,4-N-acetylglucosaminyltransferase (mouse)" RELATED [PRO:DNx, UniProtKB:Q67BJ4]
synonym: "UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase (mouse)" EXACT [UniProtKB:Q67BJ4]
xref: UniProtKB:Q67BJ4
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000003516 ! lactosylceramide 4-alpha-galactosyltransferase
relationship: has_gene_template MGI:3512453 ! A4galt (mouse)

[Term]
id: PR:000058138
name: lactosylceramide 4-alpha-galactosyltransferase O-glycosylated 2 (human)
def: "A lactosylceramide 4-alpha-galactosyltransferase (human) that has been O-glycosylated at the residue equivalent to Thr-68 of the amino acid sequence represented by UniProtKB:Q9NPC4-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q9NPC4-1, Thr-68, MOD:00005~GNO:G43417UB." [GlyGen:Q9NPC4-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hA4GALT/OGlyco:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9NPC4-1, Thr-68, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q9NPC4 ! lactosylceramide 4-alpha-galactosyltransferase (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9C949
name: lactosylceramide 4-alpha-galactosyltransferase (Arabidopsis thaliana)
def: "A lactosylceramide 4-alpha-galactosyltransferase that is encoded in the genome of Arabidopsis thaliana." [PANTHER:PTHR12042:SF4, PRO:DNx]
comment: Category=organism-gene.
synonym: "AT1G61050" RELATED Gene-based [UniProtKB:Q9C949]
synonym: "At-A4GALT" EXACT PRO-short-label [PRO:DNx]
synonym: "At1g61050" RELATED Gene-based [UniProtKB:Q9C949]
synonym: "glycosyltransferase (Arabidopsis thaliana)" BROAD [UniProtKB:Q9C949]
synonym: "uncharacterized protein T7P1.18 (Arabidopsis thaliana)" EXACT [UniProtKB:Q9C949]
synonym: "alpha 1,4-glycosyltransferase-like protein (Arabidopsis thaliana)" BROAD [UniProtKB:Q9C949]
xref: UniProtKB:Q9C949
intersection_of: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana
intersection_of: PR:000003516 ! lactosylceramide 4-alpha-galactosyltransferase
relationship: has_gene_template Araport:AT1G61050 ! T7P1.18 (Arabidopsis thaliana)