[Term] id: PR:000018803 name: insulin-like growth factor 1 receptor proteolytic cleavage product def: "An insulin-like growth factor 1 receptor that has been processed by proteolytic cleavage." [PRO:DNx] comment: Category=modification. synonym: "IGF1R/ClvPrd" EXACT PRO-short-label [PRO:DNx] intersection_of: output_of GO:0016485 ! protein processing intersection_of: PR:000003273 ! insulin-like growth factor 1 receptor [Term] id: PR:000018802 name: insulin-like growth factor 1 receptor, signal peptide removed form def: "An insulin-like growth factor 1 receptor that has had the signal peptide removed." [PRO:DNx] comment: Category=modification. synonym: "IGF1R/SigPep-" EXACT PRO-short-label [PRO:DNx] intersection_of: PR:000003273 ! insulin-like growth factor 1 receptor intersection_of: lacks_part SO:0000418 ! signal_peptide [Term] id: PR:Q60751 name: insulin-like growth factor 1 receptor (mouse) def: "An insulin-like growth factor 1 receptor that is encoded in the genome of mouse." [OMA:Q60751, PRO:DNx] comment: Category=organism-gene. synonym: "Igf1r" RELATED Gene-based [UniProtKB:Q60751] synonym: "mIGF1R" EXACT PRO-short-label [PRO:DNx] synonym: "CD221 (mouse)" EXACT [UniProtKB:Q60751] synonym: "IGF-I receptor (mouse)" EXACT [UniProtKB:Q60751] synonym: "insulin-like growth factor I receptor (mouse)" EXACT [UniProtKB:Q60751] xref: UniProtKB:Q60751 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000003273 ! insulin-like growth factor 1 receptor relationship: has_gene_template MGI:96433 ! Igf1r (mouse) [Term] id: PR:P08069 name: insulin-like growth factor 1 receptor (human) def: "An insulin-like growth factor 1 receptor that is encoded in the genome of human." [PRO:JAN, UniProtKB:P08069] comment: Category=organism-gene. synonym: "IGF1R" RELATED Gene-based [UniProtKB:P08069] synonym: "hIGF1R" EXACT PRO-short-label [PRO:DNx] synonym: "CD221 (human)" EXACT [UniProtKB:P08069] synonym: "IGF-I receptor (human)" EXACT [UniProtKB:P08069] synonym: "insulin-like growth factor I receptor (human)" EXACT [UniProtKB:P08069] xref: DTO:03100180 xref: UniProtKB:P08069 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000003273 ! insulin-like growth factor 1 receptor relationship: has_gene_template HGNC:5465 ! IGF1R (human) [Term] id: PR:000003273 name: insulin-like growth factor 1 receptor def: "An insulin receptor-related receptor that is a translation product of the human IGF1R gene or a 1:1 ortholog thereof." [PRO:JAN] comment: Category=gene. synonym: "CD221" EXACT [] synonym: "IGF1R" EXACT PRO-short-label [PRO:DNx] synonym: "IGF-I receptor" EXACT [] synonym: "insulin-like growth factor I receptor" EXACT [] xref: IUPHARobj:1801 is_a: PR:000003272 ! insulin receptor-related receptor [Term] id: PR:P08069-1 name: insulin-like growth factor 1 receptor isoform 1 (human) def: "An insulin-like growth factor 1 receptor isoform 1 that is encoded in the genome of human." [PRO:CNA] comment: Category=organism-sequence. synonym: "hIGF1R/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P08069-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000003274 ! insulin-like growth factor 1 receptor isoform 1 [Term] id: PR:P24062 name: insulin-like growth factor 1 receptor (rat) def: "An insulin-like growth factor 1 receptor that is encoded in the genome of rat." [OMA:P24062, PANTHER:PTHR24416:SF178, PRO:DNx] comment: Category=organism-gene. synonym: "Igf1r" RELATED Gene-based [UniProtKB:P24062] synonym: "rIGF1R" EXACT PRO-short-label [PRO:DNx] synonym: "CD221 (rat)" EXACT [UniProtKB:P24062] synonym: "IGF-I receptor (rat)" EXACT [UniProtKB:P24062] synonym: "insulin-like growth factor I receptor (rat)" EXACT [UniProtKB:P24062] xref: UniProtKB:P24062 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000003273 ! insulin-like growth factor 1 receptor relationship: has_gene_template RGD:2869 ! Igf1r (rat) [Term] id: PR:000003276 name: insulin-like growth factor 1 receptor isoform 1 cleaved 1 def: "An insulin-like growth factor 1 receptor isoform 1, signal peptide removed form that has been subsequently processed to yield the N-terminal mature chain." [PMID:8257688, PRO:JAN] comment: Category=modification. synonym: "IGF1R/iso:1/Clv:1" EXACT PRO-short-label [PRO:DNx] synonym: "insulin-like growth factor 1 receptor alpha chain" EXACT [] is_a: PR:000021922 ! insulin-like growth factor 1 receptor isoform 1, signal peptide removed form relationship: output_of GO:0016485 ! protein processing [Term] id: PR:000003277 name: insulin-like growth factor 1 receptor isoform 1 cleaved 2 def: "An insulin-like growth factor 1 receptor isoform 1, signal peptide removed form that has been subsequently processed to yield the C-terminal mature chain." [PRO:JAN] comment: Category=modification. synonym: "IGF1R/iso:1/Clv:2" EXACT PRO-short-label [PRO:DNx] synonym: "insulin-like growth factor 1 receptor beta chain" EXACT [] is_a: PR:000021922 ! insulin-like growth factor 1 receptor isoform 1, signal peptide removed form relationship: output_of GO:0016485 ! protein processing [Term] id: PR:000003274 name: insulin-like growth factor 1 receptor isoform 1 def: "An insulin-like growth factor 1 receptor that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08069-1 or a 1:1 ortholog thereof." [PRO:CNA] comment: Category=sequence. synonym: "IGF1R/iso:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000003273 ! insulin-like growth factor 1 receptor [Term] id: PR:000021922 name: insulin-like growth factor 1 receptor isoform 1, signal peptide removed form def: "An insulin-like growth factor 1 receptor isoform 1 that has had the signal peptide removed." [PRO:DNx] comment: Category=modification. synonym: "IGF1R/iso:1/SigPep-" EXACT PRO-short-label [PRO:DNx] intersection_of: PR:000003274 ! insulin-like growth factor 1 receptor isoform 1 intersection_of: lacks_part SO:0000418 ! signal_peptide [Term] id: PR:Q60751-1 name: insulin-like growth factor 1 receptor isoform 1 (mouse) def: "An insulin-like growth factor 1 receptor isoform 1 that is encoded in the genome of mouse." [PRO:CNA] comment: Category=organism-sequence. synonym: "mIGF1R/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q60751-1 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000003274 ! insulin-like growth factor 1 receptor isoform 1 [Term] id: PR:000054420 name: insulin-like growth factor 1 receptor O-glycosylated 1 (human) def: "An insulin-like growth factor 1 receptor (human) that has been O-glycosylated at the residue equivalent to Thr-684 of the amino acid sequence represented by UniProtKB:P08069-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P08069-1, Thr-684, MOD:00005~GNO:G43417UB." [GlyGen:P08069-1, PMID:30459171, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hIGF1R/OGlyco:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P08069-1, Thr-684, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P08069 ! insulin-like growth factor 1 receptor (human) relationship: has_part GNO:G43417UB ! G43417UB relationship: has_part MOD:00005 ! O-glycosyl-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens