[Term]
id: PR:000048884
name: serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform phosphorylated 1 (human)
def: "A serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (human) that has been post-translationally modified to include phosphotyrosine at position 307 of the amino acid sequence represented by UniProtKB:P67775. UniProtKB:P67775, Tyr-307, MOD:00048." [PRO:DNx, Reactome:R-HSA-8857939]
comment: Category=organism-modification.
synonym: "hPPP2CA/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P67775, Tyr-307, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-8857939 "PR:000048884 located_in GO:0005829"
is_a: PR:P67775 ! serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P63330
name: serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (mouse)
def: "A serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform that is encoded in the genome of mouse." [OMA:P63330, PRO:DNx]
comment: Category=organism-gene.
synonym: "Ppp2ca" RELATED Gene-based [UniProtKB:P63330]
synonym: "mPPP2CA" EXACT PRO-short-label [PRO:DNx]
synonym: "PP2A-alpha (mouse)" EXACT [UniProtKB:P63330]
xref: UniProtKB:P63330
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000003211 ! serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
relationship: has_gene_template MGI:1321159 ! Ppp2ca (mouse)

[Term]
id: PR:P63331
name: serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (rat)
def: "A serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform that is encoded in the genome of rat." [OMA:P63331, PRO:DNx]
comment: Category=organism-gene.
synonym: "Ppp2ca" RELATED Gene-based [UniProtKB:P63331]
synonym: "rPPP2CA" EXACT PRO-short-label [PRO:DNx]
synonym: "PP2A-alpha (rat)" EXACT [UniProtKB:P63331]
xref: UniProtKB:P63331
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000003211 ! serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
relationship: has_gene_template RGD:3380 ! Ppp2ca (rat)

[Term]
id: PR:000003211
name: serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
def: "A conventional serine/threonine-protein phosphatase that is a translation product of the human PPP2CA gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "RP-C" EXACT []
synonym: "PPP2CA" EXACT PRO-short-label [PRO:DNx]
synonym: "PP2A-alpha" EXACT []
synonym: "replication protein C" EXACT []
is_a: PR:000003208 ! conventional serine/threonine-protein phosphatase

[Term]
id: PR:P67777
name: serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (rabbit)
def: "A serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform that is encoded in the genome of rabbit." [OMA:P67777, PRO:DNx]
comment: Category=organism-gene. Requested by=PubChem.
synonym: "PPP2CA" RELATED Gene-based [UniProtKB:P67777]
synonym: "rabbit-PPP2CA" EXACT PRO-short-label [PRO:DNx]
synonym: "PP2A-alpha (rabbit)" EXACT [UniProtKB:P67777]
xref: UniProtKB:P67777
intersection_of: only_in_taxon NCBITaxon:9986 ! Oryctolagus cuniculus
intersection_of: PR:000003211 ! serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
relationship: has_gene_template NCBIGene:100009252 ! PPP2CA (rabbit)

[Term]
id: PR:P67775-1
name: serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform isoform h1 (human)
def: "A serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P67775-1." [PRO:DNx, UniProtKB:P67775]
comment: Category=organism-sequence.
synonym: "hPPP2CA/iso:h1" EXACT PRO-short-label [PRO:DNx]
synonym: "serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform isoform PP2Acalpha1 (human)" EXACT [UniProtKB:P67775]
xref: UniProtKB:P67775-1
is_a: PR:P67775 ! serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P67775-2
name: serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform isoform h2 (human)
def: "A serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P67775-2." [PRO:DNx, UniProtKB:P67775]
comment: Category=organism-sequence.
synonym: "hPPP2CA/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform isoform PP2Acalpha2 (human)" EXACT [UniProtKB:P67775]
xref: UniProtKB:P67775-2
is_a: PR:P67775 ! serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P67774
name: serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (cow)
def: "A serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform that is encoded in the genome of cow." [OMA:P67774, PRO:DNx]
comment: Category=organism-gene.
synonym: "PPP2CA" RELATED Gene-based [UniProtKB:P67774]
synonym: "cow-PPP2CA" EXACT PRO-short-label [PRO:DNx]
synonym: "PP2A-alpha (cow)" EXACT [UniProtKB:P67774]
xref: UniProtKB:P67774
intersection_of: only_in_taxon NCBITaxon:9913 ! Bos taurus
intersection_of: PR:000003211 ! serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
relationship: has_gene_template NCBIGene:282320 ! PPP2CA (cow)

[Term]
id: PR:P67775
name: serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (human)
def: "A serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform that is encoded in the genome of human." [PRO:CNA, UniProtKB:P67775]
comment: Category=organism-gene.
synonym: "PPP2CA" RELATED Gene-based [UniProtKB:P67775]
synonym: "hPPP2CA" EXACT PRO-short-label [PRO:DNx]
synonym: "RP-C (human)" EXACT [UniProtKB:P67775]
synonym: "PP2A-alpha (human)" EXACT [UniProtKB:P67775]
synonym: "replication protein C (human)" EXACT [UniProtKB:P67775]
xref: UniProtKB:P67775
xref: Reactome:R-HSA-165971 "PR:P67775 located_in GO:0005829"
xref: Reactome:R-HSA-165978 "PR:P67775 located_in GO:0005654"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003211 ! serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
relationship: has_gene_template HGNC:9299 ! PPP2CA (human)

[Term]
id: PR:000046188
name: serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform phosphorylated 1 (mouse)
def: "A serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (mouse) that has been phosphorylated at Tyr-307. UniProtKB:P63330, Tyr-307, MOD:00048." [PMID:7510677, iPTMnet:P63330]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:7510677). Status=unreviewed.
synonym: "mPPP2CA/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P63330, Tyr-307, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P63330 ! serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (mouse)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus