[Term] id: PR:000003209 name: serine/threonine-protein phosphatase PP1-alpha catalytic subunit def: "A conventional serine/threonine-protein phosphatase that is a translation product of the human PPP1CA gene or a 1:1 ortholog thereof." [PRO:CNA] comment: Category=gene. synonym: "PP-1A" EXACT [] synonym: "PPP1A" RELATED Gene-based [] synonym: "PPP1CA" EXACT PRO-short-label [PRO:DNx] is_a: PR:000003208 ! conventional serine/threonine-protein phosphatase [Term] id: PR:P62136 name: serine/threonine-protein phosphatase PP1-alpha catalytic subunit (human) def: "A serine/threonine-protein phosphatase PP1-alpha catalytic subunit that is encoded in the genome of human." [PRO:CNA, UniProtKB:P62136] comment: Category=organism-gene. synonym: "PPP1A" RELATED Gene-based [UniProtKB:P62136] synonym: "PPP1CA" RELATED Gene-based [UniProtKB:P62136] synonym: "hPPP1CA" EXACT PRO-short-label [PRO:DNx] synonym: "PP-1A (human)" EXACT [UniProtKB:P62136] xref: UniProtKB:P62136 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000003209 ! serine/threonine-protein phosphatase PP1-alpha catalytic subunit relationship: has_gene_template HGNC:9281 ! PPP1CA (human) [Term] id: PR:000048863 name: serine/threonine-protein phosphatase PP1-alpha catalytic subunit, initiator methionine removed form (human) def: "A serine/threonine-protein phosphatase PP1-alpha catalytic subunit (human) that has had the initiator methionine removed. UniProtKB:P62136, 2-330." [PRO:DNx, Reactome:R-HSA-163525] comment: Category=organism-modification. synonym: "PRO_0000058774" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "hPPP1CA/InitMet-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P62136, 2-330" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-163525 "PR:000048863 located_in GO:0005829" intersection_of: lacks_part PR:000021937 ! initiator methionine intersection_of: PR:P62136 ! serine/threonine-protein phosphatase PP1-alpha catalytic subunit (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P62136-2 name: serine/threonine-protein phosphatase PP1-alpha catalytic subunit isoform h2 (human) def: "A serine/threonine-protein phosphatase PP1-alpha catalytic subunit (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P62136-2." [PRO:DNx, UniProtKB:P62136] comment: Category=organism-sequence. synonym: "hPPP1CA/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P62136-2 is_a: PR:P62136 ! serine/threonine-protein phosphatase PP1-alpha catalytic subunit (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P62136-3 name: serine/threonine-protein phosphatase PP1-alpha catalytic subunit isoform h3 (human) def: "A serine/threonine-protein phosphatase PP1-alpha catalytic subunit (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P62136-3." [PRO:DNx, UniProtKB:P62136] comment: Category=organism-sequence. synonym: "hPPP1CA/iso:h3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P62136-3 is_a: PR:P62136 ! serine/threonine-protein phosphatase PP1-alpha catalytic subunit (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P62136-1 name: serine/threonine-protein phosphatase PP1-alpha catalytic subunit isoform 1 (human) def: "A serine/threonine-protein phosphatase PP1-alpha catalytic subunit isoform 1 that is encoded in the genome of human." [PRO:DNx] comment: Category=organism-sequence. synonym: "hPPP1CA/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P62136-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000039976 ! serine/threonine-protein phosphatase PP1-alpha catalytic subunit isoform 1