[Term]
id: PR:000003199
name: calcium/calmodulin-dependent protein kinase type II subunit alpha
def: "A calcium/calmodulin-dependent protein kinase type II chain that is a translation product of the human CAMK2A gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "CAMKA" RELATED Gene-based []
synonym: "CAMK2A" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA0968" RELATED Gene-based []
synonym: "CaMK-II subunit alpha" EXACT []
synonym: "CaM kinase II subunit alpha" EXACT []
synonym: "calcium/calmodulin-dependent protein kinase type II alpha chain" EXACT []
xref: IUPHARobj:1555
is_a: PR:000003197 ! calcium/calmodulin-dependent protein kinase type II chain

[Term]
id: PR:000046554
name: calcium/calmodulin-dependent protein kinase type II subunit alpha phosphorylated 1 (human)
def: "A calcium/calmodulin-dependent protein kinase type II subunit alpha (human) that has been post-translationally modified to include phosphothreonine at position 286 of the amino acid sequence represented by UniProtKB:Q9UQM7. UniProtKB:Q9UQM7, Thr-286, MOD:00047." [PRO:DNx, Reactome:R-HSA-416999, Reactome:R-HSA-432796, Reactome:R-HSA-444797, Reactome:R-HSA-445368]
comment: Category=organism-modification.
synonym: "hCAMK2A/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9UQM7, Thr-286, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-416999 "PR:000046554 located_in GO:0030666"
xref: Reactome:R-HSA-432796 "PR:000046554 located_in GO:0005886"
xref: Reactome:R-HSA-444797 "PR:000046554 located_in GO:0005654"
xref: Reactome:R-HSA-445368 "PR:000046554 located_in GO:0005829"
is_a: PR:Q9UQM7 ! calcium/calmodulin-dependent protein kinase type II subunit alpha (human)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000046555
name: calcium/calmodulin-dependent protein kinase type II subunit alpha phosphorylated 2 (human)
def: "A calcium/calmodulin-dependent protein kinase type II subunit alpha (human) that has been post-translationally modified to include phosphothreonine at positions 286, 305 and 306 of the amino acid sequence represented by UniProtKB:Q9UQM7. UniProtKB:Q9UQM7, Thr-286/Thr-305/Thr-306, MOD:00047." [PRO:DNx, Reactome:R-HSA-4332334]
comment: Category=organism-modification.
synonym: "hCAMK2A/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9UQM7, Thr-286/Thr-305/Thr-306, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-4332334 "PR:000046555 located_in GO:0005829"
is_a: PR:Q9UQM7 ! calcium/calmodulin-dependent protein kinase type II subunit alpha (human)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9UQM7
name: calcium/calmodulin-dependent protein kinase type II subunit alpha (human)
def: "A calcium/calmodulin-dependent protein kinase type II subunit alpha that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q9UQM7]
comment: Category=organism-gene.
synonym: "CAMKA" RELATED Gene-based [UniProtKB:Q9UQM7]
synonym: "CAMK2A" RELATED Gene-based [UniProtKB:Q9UQM7]
synonym: "hCAMK2A" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA0968" RELATED Gene-based [UniProtKB:Q9UQM7]
synonym: "CaMK-II subunit alpha (human)" EXACT [UniProtKB:Q9UQM7]
synonym: "CaM kinase II subunit alpha (human)" EXACT [UniProtKB:Q9UQM7]
xref: UniProtKB:Q9UQM7
xref: Reactome:R-HSA-4332329 "PR:Q9UQM7 located_in GO:0005829"
xref: DTO:03100218
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003199 ! calcium/calmodulin-dependent protein kinase type II subunit alpha
relationship: has_gene_template HGNC:1460 ! CAMK2A (human)

[Term]
id: PR:Q9UQM7-1
name: calcium/calmodulin-dependent protein kinase type II subunit alpha isoform A (human)
def: "A calcium/calmodulin-dependent protein kinase type II subunit alpha isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence. Requested by=PubChem.
synonym: "hCAMK2A/iso:A" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9UQM7-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000044059 ! calcium/calmodulin-dependent protein kinase type II subunit alpha isoform 1

[Term]
id: PR:Q9UQM7-2
name: calcium/calmodulin-dependent protein kinase type II subunit alpha isoform B (human)
def: "A calcium/calmodulin-dependent protein kinase type II subunit alpha (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UQM7-2." [PRO:DNx, UniProtKB:Q9UQM7]
comment: Category=organism-sequence.
synonym: "hCAMK2A/iso:B" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9UQM7-2
is_a: PR:Q9UQM7 ! calcium/calmodulin-dependent protein kinase type II subunit alpha (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens