[Term]
id: PR:000003113
name: nuclear factor of activated T-cells, cytoplasmic 1
def: "An NFAT protein that is a translation product of the human NFATC1 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "NFAT2" RELATED Gene-based []
synonym: "NFATC" RELATED Gene-based []
synonym: "NFATc" EXACT []
synonym: "NF-ATc" EXACT []
synonym: "NFATC1" EXACT PRO-short-label [PRO:DNx]
synonym: "NFATc1" EXACT []
synonym: "NF-ATc1" EXACT []
synonym: "NFAT transcription complex cytosolic component" EXACT []
is_a: PR:000003112 ! NFAT protein

[Term]
id: PR:O95644
name: nuclear factor of activated T-cells, cytoplasmic 1 (human)
def: "A nuclear factor of activated T-cells, cytoplasmic 1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:O95644]
comment: Category=organism-gene.
synonym: "NFAT2" RELATED Gene-based [UniProtKB:O95644]
synonym: "NFATC" RELATED Gene-based [UniProtKB:O95644]
synonym: "NFATC1" RELATED Gene-based [UniProtKB:O95644]
synonym: "hNFATC1" EXACT PRO-short-label [PRO:DNx]
synonym: "NF-ATc (human)" EXACT [UniProtKB:O95644]
synonym: "NFATc1 (human)" EXACT [UniProtKB:O95644]
synonym: "NF-ATc1 (human)" EXACT [UniProtKB:O95644]
synonym: "NFAT transcription complex cytosolic component (human)" EXACT [UniProtKB:O95644]
xref: UniProtKB:O95644
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003113 ! nuclear factor of activated T-cells, cytoplasmic 1
relationship: has_gene_template HGNC:7775 ! NFATC1 (human)

[Term]
id: PR:O95644-17
name: nuclear factor of activated T-cells, cytoplasmic 1 isoform h10 (human)
def: "A nuclear factor of activated T-cells, cytoplasmic 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O95644-17." [PRO:DNx, UniProtKB:O95644]
comment: Category=organism-sequence.
synonym: "hNFATC1/iso:h10" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O95644-17
is_a: PR:O95644 ! nuclear factor of activated T-cells, cytoplasmic 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O95644-11
name: nuclear factor of activated T-cells, cytoplasmic 1 isoform IB-deltaIX (human)
def: "A nuclear factor of activated T-cells, cytoplasmic 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O95644-11." [PRO:DNx, UniProtKB:O95644]
comment: Category=organism-sequence.
synonym: "hNFATC1/iso:IB-deltaIX" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O95644-11
is_a: PR:O95644 ! nuclear factor of activated T-cells, cytoplasmic 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O95644-10
name: nuclear factor of activated T-cells, cytoplasmic 1 isoform IA-deltaIX (human)
def: "A nuclear factor of activated T-cells, cytoplasmic 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O95644-10." [PRO:DNx, UniProtKB:O95644]
comment: Category=organism-sequence.
synonym: "hNFATC1/iso:IA-deltaIX" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O95644-10
is_a: PR:O95644 ! nuclear factor of activated T-cells, cytoplasmic 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O95644-8
name: nuclear factor of activated T-cells, cytoplasmic 1 isoform A-alpha' (human)
def: "A nuclear factor of activated T-cells, cytoplasmic 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O95644-8." [PRO:DNx, UniProtKB:O95644]
comment: Category=organism-sequence.
synonym: "hNFATC1/iso:A-alpha'" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O95644-8
is_a: PR:O95644 ! nuclear factor of activated T-cells, cytoplasmic 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O95644-1
name: nuclear factor of activated T-cells, cytoplasmic 1 isoform C-alpha (human)
def: "A nuclear factor of activated T-cells, cytoplasmic 1 isoform 1 that is encoded in the genome of human." [PRO:JAN]
comment: Category=organism-sequence.
synonym: "hNFATC1/iso:C-alpha" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O95644-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003114 ! nuclear factor of activated T-cells, cytoplasmic 1 isoform 1

[Term]
id: PR:O95644-3
name: nuclear factor of activated T-cells, cytoplasmic 1 isoform A-beta (human)
def: "A nuclear factor of activated T-cells, cytoplasmic 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O95644-3." [PRO:DNx, UniProtKB:O95644]
comment: Category=organism-sequence.
synonym: "hNFATC1/iso:A-beta" EXACT PRO-short-label [PRO:DNx]
synonym: "nuclear factor of activated T-cells, cytoplasmic 1 isoform IB-VIII (human)" EXACT [UniProtKB:O95644]
xref: UniProtKB:O95644-3
is_a: PR:O95644 ! nuclear factor of activated T-cells, cytoplasmic 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O95644-2
name: nuclear factor of activated T-cells, cytoplasmic 1 isoform A-alpha (human)
def: "A nuclear factor of activated T-cells, cytoplasmic 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O95644-2." [PRO:DNx, UniProtKB:O95644]
comment: Category=organism-sequence.
synonym: "hNFATC1/iso:A-alpha" EXACT PRO-short-label [PRO:DNx]
synonym: "nuclear factor of activated T-cells, cytoplasmic 1 isoform IA-VIII (human)" EXACT [UniProtKB:O95644]
xref: UniProtKB:O95644-2
is_a: PR:O95644 ! nuclear factor of activated T-cells, cytoplasmic 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O95644-5
name: nuclear factor of activated T-cells, cytoplasmic 1 isoform B-beta (human)
def: "A nuclear factor of activated T-cells, cytoplasmic 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O95644-5." [PRO:DNx, UniProtKB:O95644]
comment: Category=organism-sequence.
synonym: "hNFATC1/iso:B-beta" EXACT PRO-short-label [PRO:DNx]
synonym: "nuclear factor of activated T-cells, cytoplasmic 1 isoform IB-IXS (human)" EXACT [UniProtKB:O95644]
xref: UniProtKB:O95644-5
is_a: PR:O95644 ! nuclear factor of activated T-cells, cytoplasmic 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O95644-4
name: nuclear factor of activated T-cells, cytoplasmic 1 isoform B-alpha (human)
def: "A nuclear factor of activated T-cells, cytoplasmic 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O95644-4." [PRO:DNx, UniProtKB:O95644]
comment: Category=organism-sequence.
synonym: "hNFATC1/iso:B-alpha" EXACT PRO-short-label [PRO:DNx]
synonym: "nuclear factor of activated T-cells, cytoplasmic 1 isoform IA-IXS (human)" EXACT [UniProtKB:O95644]
xref: UniProtKB:O95644-4
is_a: PR:O95644 ! nuclear factor of activated T-cells, cytoplasmic 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O95644-6
name: nuclear factor of activated T-cells, cytoplasmic 1 isoform C-beta (human)
def: "A nuclear factor of activated T-cells, cytoplasmic 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O95644-6." [PRO:DNx, UniProtKB:O95644]
comment: Category=organism-sequence.
synonym: "hNFATC1/iso:C-beta" EXACT PRO-short-label [PRO:DNx]
synonym: "nuclear factor of activated T-cells, cytoplasmic 1 isoform IB-IXL (human)" EXACT [UniProtKB:O95644]
xref: UniProtKB:O95644-6
is_a: PR:O95644 ! nuclear factor of activated T-cells, cytoplasmic 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000048589
name: nuclear factor of activated T-cells, cytoplasmic 1 phosphorylated 3 (human)
def: "A nuclear factor of activated T-cells, cytoplasmic 1 (human) that has been post-translationally modified to include phosphoserine at position 257 of the amino acid sequence represented by UniProtKB:O95644. UniProtKB:O95644, Ser-257, MOD:00046." [PRO:DNx, Reactome:R-HSA-2025935, Reactome:R-HSA-2685618]
comment: Category=organism-modification.
synonym: "hNFATC1/Phos:3" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O95644, Ser-257, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2025935 "PR:000048589 located_in GO:0005654"
xref: Reactome:R-HSA-2685618 "PR:000048589 located_in GO:0005829"
is_a: PR:O95644 ! nuclear factor of activated T-cells, cytoplasmic 1 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000048588
name: nuclear factor of activated T-cells, cytoplasmic 1 phosphorylated 2 (human)
def: "A nuclear factor of activated T-cells, cytoplasmic 1 (human) that has been post-translationally modified to include phosphoserine at positions 175, 176, 178, 179, 181, 233, 237, 241, 257, 278, 286 and 290 of the amino acid sequence represented by UniProtKB:O95644. UniProtKB:O95644, Ser-175/Ser-176/Ser-178/Ser-179/Ser-181/Ser-233/Ser-237/Ser-241/Ser-257/Ser-278/Ser-286/Ser-290, MOD:00046." [PRO:DNx, Reactome:R-HSA-2025953]
comment: Category=organism-modification.
synonym: "hNFATC1/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O95644, Ser-175/Ser-176/Ser-178/Ser-179/Ser-181/Ser-233/Ser-237/Ser-241/Ser-257/Ser-278/Ser-286/Ser-290, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2025953 "PR:000048588 located_in GO:0005829"
is_a: PR:O95644 ! nuclear factor of activated T-cells, cytoplasmic 1 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000036638
name: nuclear factor of activated T-cells, cytoplasmic 1 isoform 1 phosphorylated 1 (human)
def: "A nuclear factor of activated T-cells, cytoplasmic 1 isoform 1 phosphorylated 1 in human. UniProtKB:O95644-1, Ser-117/Ser-172, MOD:00046." [PMID:10866678, PRO:JAN]
comment: Category=organism-modification.
synonym: "hNFATC1/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O95644-1, Ser-117/Ser-172, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003116 ! nuclear factor of activated T-cells, cytoplasmic 1 isoform 1 phosphorylated 1
relationship: has_part MOD:00046 ! O-phospho-L-serine