[Term]
id: PR:000003107
name: mitogen-activated protein kinase 14
def: "A map kinase p38 that is a translation product of the human MAPK14 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "CRK1" EXACT []
synonym: "CSBP" RELATED Gene-based []
synonym: "MXI2" RELATED Gene-based []
synonym: "CSBP1" RELATED Gene-based []
synonym: "CSBP2" RELATED Gene-based []
synonym: "CSPB1" RELATED Gene-based []
synonym: "MAPK14" EXACT PRO-short-label [PRO:DNx]
synonym: "SAPK2A" RELATED Gene-based []
synonym: "MAPK 14" EXACT []
synonym: "MAP kinase 14" EXACT []
synonym: "MAP kinase MXI2" EXACT []
synonym: "MAP kinase p38 alpha" EXACT []
synonym: "CSAID-binding protein" EXACT []
synonym: "MAX-interacting protein 2" EXACT []
synonym: "mitogen-activated protein kinase p38 alpha" EXACT []
synonym: "cytokine suppressive anti-inflammatory drug-binding protein" EXACT []
xref: IUPHARobj:1499
is_a: PR:000003106 ! map kinase p38

[Term]
id: PR:Q16539-1
name: mitogen-activated protein kinase 14 isoform CSBP2 (human)
def: "A mitogen-activated protein kinase 14 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence. Requested by=PubChem.
synonym: "hMAPK14/iso:CSBP2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q16539-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000040708 ! mitogen-activated protein kinase 14 isoform 1

[Term]
id: PR:Q16539-3
name: mitogen-activated protein kinase 14 isoform hMxi2 (human)
def: "A mitogen-activated protein kinase 14 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q16539-3." [PRO:DNx, UniProtKB:Q16539]
comment: Category=organism-sequence.
synonym: "hMAPK14/iso:hMxi2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q16539-3
is_a: PR:Q16539 ! mitogen-activated protein kinase 14 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q16539-2
name: mitogen-activated protein kinase 14 isoform CSBP1 (human)
def: "A mitogen-activated protein kinase 14 isoform 2 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hMAPK14/iso:CSBP1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q16539-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000040709 ! mitogen-activated protein kinase 14 isoform 2

[Term]
id: PR:Q16539-5
name: mitogen-activated protein kinase 14 isoform h5 (human)
def: "A mitogen-activated protein kinase 14 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q16539-5." [PRO:DNx, UniProtKB:Q16539]
comment: Category=organism-sequence.
synonym: "hMAPK14/iso:h5" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q16539-5
is_a: PR:Q16539 ! mitogen-activated protein kinase 14 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q16539-4
name: mitogen-activated protein kinase 14 isoform Exip (human)
def: "A mitogen-activated protein kinase 14 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q16539-4." [PRO:DNx, UniProtKB:Q16539]
comment: Category=organism-sequence.
synonym: "hMAPK14/iso:Exip" EXACT PRO-short-label [PRO:DNx]
synonym: "mitogen-activated protein kinase 14 isoform Exon skip (human)" EXACT [UniProtKB:Q16539]
xref: UniProtKB:Q16539-4
is_a: PR:Q16539 ! mitogen-activated protein kinase 14 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q16539
name: mitogen-activated protein kinase 14 (human)
def: "A mitogen-activated protein kinase 14 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q16539]
comment: Category=organism-gene.
synonym: "CSBP" RELATED Gene-based [UniProtKB:Q16539]
synonym: "MXI2" RELATED Gene-based [UniProtKB:Q16539]
synonym: "CSBP1" RELATED Gene-based [UniProtKB:Q16539]
synonym: "CSBP2" RELATED Gene-based [UniProtKB:Q16539]
synonym: "CSPB1" RELATED Gene-based [UniProtKB:Q16539]
synonym: "MAPK14" RELATED Gene-based [UniProtKB:Q16539]
synonym: "SAPK2A" RELATED Gene-based [UniProtKB:Q16539]
synonym: "hMAPK14" EXACT PRO-short-label [PRO:DNx]
synonym: "MAPK 14 (human)" EXACT [UniProtKB:Q16539]
synonym: "MAP kinase 14 (human)" EXACT [UniProtKB:Q16539]
synonym: "MAP kinase MXI2 (human)" EXACT [UniProtKB:Q16539]
synonym: "MAP kinase p38 alpha (human)" EXACT [UniProtKB:Q16539]
synonym: "CSAID-binding protein (human)" EXACT [UniProtKB:Q16539]
synonym: "MAX-interacting protein 2 (human)" EXACT [UniProtKB:Q16539]
synonym: "stress-activated protein kinase 2a (human)" EXACT [UniProtKB:Q16539]
synonym: "mitogen-activated protein kinase p38 alpha (human)" EXACT [UniProtKB:Q16539]
synonym: "cytokine suppressive anti-inflammatory drug-binding protein (human)" EXACT [UniProtKB:Q16539]
xref: DTO:03100326
xref: UniProtKB:Q16539
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003107 ! mitogen-activated protein kinase 14
relationship: has_gene_template HGNC:6876 ! MAPK14 (human)

[Term]
id: PR:000036637
name: mitogen-activated protein kinase 14 phosphorylated 1 (human)
def: "A mitogen-activated protein kinase 14 phosphorylated 1 in human. Example: UniProtKB:Q16539-1, Thr-180, MOD:00047|Tyr-182, MOD:00048." [PMID:15642743, PRO:CL]
comment: Category=organism-modification.
synonym: "hMAPK14/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q16539-1, Thr-180, MOD:00047|Tyr-182, MOD:00048" NARROW PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003109 ! mitogen-activated protein kinase 14 phosphorylated 1
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine

[Term]
id: PR:000048320
name: mitogen-activated protein kinase 14, initiator methionine removed phosphorylated 1 (human)
def: "A mitogen-activated protein kinase 14 (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphothreonine at position 180, and phosphotyrosine at position 182 of the amino acid sequence represented by UniProtKB:Q16539. UniProtKB:Q16539, 2-360, Thr-180, MOD:00047|Tyr-182, MOD:00048." [PRO:DNx, Reactome:R-HSA-428935, Reactome:R-HSA-446227]
comment: Category=organism-modification.
synonym: "hMAPK14/InitMet-/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000186291, Thr-180, MOD:00047|Tyr-182, MOD:00048" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:Q16539, 2-360, Thr-180, MOD:00047|Tyr-182, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-428935 "PR:000048320 located_in GO:0005829"
xref: Reactome:R-HSA-446227 "PR:000048320 located_in GO:0005654"
is_a: PR:Q16539 ! mitogen-activated protein kinase 14 (human)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:000048319
name: mitogen-activated protein kinase 14, initiator methionine removed form (human)
def: "A mitogen-activated protein kinase 14 (human) that has had the initiator methionine removed. UniProtKB:Q16539, 2-360." [PRO:DNx, Reactome:R-HSA-428933, Reactome:R-HSA-446223]
comment: Category=organism-modification.
synonym: "PRO_0000186291" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hMAPK14/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q16539, 2-360" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-428933 "PR:000048319 located_in GO:0005829"
xref: Reactome:R-HSA-446223 "PR:000048319 located_in GO:0005654"
xref: Reactome:R-HSA-6803280 "PR:000048319 located_in GO:1904813"
xref: Reactome:R-HSA-6803300 "PR:000048319 located_in GO:0034774"
xref: Reactome:R-HSA-6806453 "PR:000048319 located_in GO:0005576"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:Q16539 ! mitogen-activated protein kinase 14 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens