[Term]
id: PR:000003041
name: serine/threonine-protein kinase mTOR
def: "A protein that is a translation product of the human MTOR gene or a 1:1 ortholog thereof." [PRO:CL]
comment: Category=gene.
synonym: "FRAP" RELATED Gene-based []
synonym: "MTOR" EXACT PRO-short-label [PRO:DNx]
synonym: "mTOR" EXACT []
synonym: "FRAP1" RELATED Gene-based []
synonym: "FRAP2" RELATED Gene-based []
synonym: "RAFT1" RELATED Gene-based []
synonym: "RAPT1" RELATED Gene-based []
synonym: "rapamycin target protein 1" EXACT []
synonym: "mammalian target of rapamycin" EXACT []
synonym: "mechanistic target of rapamycin" EXACT []
synonym: "FKBP12-rapamycin complex-associated protein" EXACT []
synonym: "FK506-binding protein 12-rapamycin complex-associated protein 1" EXACT []
xref: IUPHARobj:2109
is_a: PR:000000001 ! protein

[Term]
id: PR:Q9JLN9
name: serine/threonine-protein kinase mTOR (mouse)
def: "A serine/threonine-protein kinase mTOR that is encoded in the genome of mouse." [OMA:Q9JLN9, PRO:DNx]
comment: Category=organism-gene.
synonym: "Frap" RELATED Gene-based [UniProtKB:Q9JLN9]
synonym: "Mtor" RELATED Gene-based [UniProtKB:Q9JLN9]
synonym: "Frap1" RELATED Gene-based [UniProtKB:Q9JLN9]
synonym: "mMTOR" EXACT PRO-short-label [PRO:DNx]
synonym: "RAPT1 (mouse)" EXACT [UniProtKB:Q9JLN9]
synonym: "rapamycin target protein 1 (mouse)" EXACT [UniProtKB:Q9JLN9]
synonym: "mammalian target of rapamycin (mouse)" EXACT [UniProtKB:Q9JLN9]
synonym: "mechanistic target of rapamycin (mouse)" EXACT [UniProtKB:Q9JLN9]
synonym: "FKBP12-rapamycin complex-associated protein (mouse)" EXACT [UniProtKB:Q9JLN9]
synonym: "FK506-binding protein 12-rapamycin complex-associated protein 1 (mouse)" EXACT [UniProtKB:Q9JLN9]
xref: UniProtKB:Q9JLN9
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000003041 ! serine/threonine-protein kinase mTOR
relationship: has_gene_template MGI:1928394 ! Mtor (mouse)

[Term]
id: PR:Q9JLN9-2
name: serine/threonine-protein kinase mTOR isoform m2 (mouse)
def: "A serine/threonine-protein kinase mTOR (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9JLN9-2." [PRO:DNx, UniProtKB:Q9JLN9]
comment: Category=organism-sequence.
synonym: "mMTOR/iso:m2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9JLN9-2
is_a: PR:Q9JLN9 ! serine/threonine-protein kinase mTOR (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000050320
name: serine/threonine-protein kinase mTOR isoform 1 phosphorylated 1 (mouse)
def: "A serine/threonine-protein kinase mTOR isoform 1 (mouse) that has been phosphorylated at the position equivalent to Ser-2448 of the amino acid sequence represented by UniProtKB:Q9JLN9-1. UniProtKB:Q9JLN9-1, Ser-2448, MOD:00046." [PMID:10567225, PRO:LN]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:10567225).
synonym: "mMTOR/iso:1/Phos:1" EXACT PRO-short-label [PRO:KER]
synonym: "UniProtKB:Q9JLN9-1, Ser-2448, MOD:00046" EXACT PRO-proteoform-std [PRO:KER]
is_a: PR:Q9JLN9-1 ! serine/threonine-protein kinase mTOR isoform 1 (mouse)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000050321
name: serine/threonine-protein kinase mTOR isoform 1 unphosphorylated 1 (mouse)
def: "A serine/threonine-protein kinase mTOR isoform 1 (mouse) that is unphosphorylated at at position equivalent to Ser-2448 of the amino acid sequence represented by UniProtKB:Q9JLN9-1. UniProtKB:Q9JLN9-1, Ser-2448, PR:000026291." [PMID:10567225, PRO:LN]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:10567225).
synonym: "mMTOR/iso:1/UnPhos:1" EXACT PRO-short-label [PRO:KER]
synonym: "UniProtKB:Q9JLN9-1, Ser-2448, PR:000026291" EXACT PRO-proteoform-std [PRO:KER]
is_a: PR:Q9JLN9-1 ! serine/threonine-protein kinase mTOR isoform 1 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q9JLN9-1
name: serine/threonine-protein kinase mTOR isoform 1 (mouse)
def: "A serine/threonine-protein kinase mTOR isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mMTOR/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9JLN9-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000039438 ! serine/threonine-protein kinase mTOR isoform 1