[Term]
id: PR:000003033
name: leucine-rich repeat serine/threonine-protein kinase 2
def: "A protein that is a translation product of the human LRRK2 gene or a 1:1 ortholog thereof. LRRK2 belongs to a gene family known as Roco. Roco genes encode for large proteins that have a characteristic GTPase domain, named Roc, plus a domain of unknown function called COR. Several Roco proteins also contain a protein kinase domain. Leucine-rich repeat serine/threonine-protein kinase 2 contains an N-terminal repeat that is unique to this protein." [PMID:16966681, PRO:CNA]
comment: Category=gene.
synonym: "LRRK2" EXACT PRO-short-label [PRO:DNx]
synonym: "PARK8" RELATED Gene-based []
synonym: "dardarin" EXACT []
xref: IUPHARobj:2059
is_a: PR:000000001 ! protein