[Term]
id: PR:P06240
name: proto-oncogene tyrosine-protein kinase LCK (mouse)
def: "A tyrosine-protein kinase Lck that is encoded in the genome of mouse." [OMA:P06240, PRO:CNA]
comment: Category=organism-gene.
synonym: "Lck" RELATED Gene-based [UniProtKB:P06240]
synonym: "mLCK" EXACT PRO-short-label [PRO:DNx]
synonym: "Lsk-t" RELATED Gene-based [UniProtKB:P06240]
synonym: "LSK (mouse)" EXACT [UniProtKB:P06240]
synonym: "p56-LCK (mouse)" EXACT [UniProtKB:P06240]
synonym: "leukocyte C-terminal Src kinase (mouse)" EXACT [UniProtKB:P06240]
synonym: "lymphocyte cell-specific protein-tyrosine kinase (mouse)" EXACT [UniProtKB:P06240]
xref: UniProtKB:P06240
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000002998 ! tyrosine-protein kinase Lck
relationship: has_gene_template MGI:96756 ! Lck (mouse)

[Term]
id: PR:000002998
name: tyrosine-protein kinase Lck
def: "A proto-oncogene SRC-like tyrosine-protein kinase that is a translation product of the human LCK gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "LCK" EXACT PRO-short-label [PRO:DNx]
synonym: "LSK" EXACT []
synonym: "Lsk-t" RELATED Gene-based []
synonym: "p56-LCK" EXACT []
synonym: "proto-oncogene Lck" EXACT []
synonym: "leukocyte C-terminal Src kinase" EXACT []
synonym: "T cell-specific protein-tyrosine kinase" EXACT []
synonym: "proto-oncogene tyrosine-protein kinase lck" EXACT []
synonym: "lymphocyte cell-specific protein-tyrosine kinase" EXACT []
xref: IUPHARobj:2053
is_a: PR:000002997 ! proto-oncogene SRC-like tyrosine-protein kinase

[Term]
id: PR:P06240-1
name: proto-oncogene tyrosine-protein kinase LCK isoform 1 (mouse)
def: "A tyrosine-protein kinase Lck isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "mLCK/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P06240-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000002999 ! tyrosine-protein kinase Lck isoform 1

[Term]
id: PR:000045642
name: proto-oncogene tyrosine-protein kinase LCK phosphorylated 1 (mouse)
def: "A proto-oncogene tyrosine-protein kinase LCK (mouse) that has been phosphorylated at Tyr-505. UniProtKB:P06240, Tyr-505, MOD:00048." [PMID:8413300, iPTMnet:P06240]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:8413300). Status=unreviewed.
synonym: "mLCK/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P06240, Tyr-505, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P06240 ! proto-oncogene tyrosine-protein kinase LCK (mouse)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000049825
name: proto-oncogene tyrosine-protein kinase LCK phosphorylated 3 (mouse)
def: "A proto-oncogene tyrosine-protein kinase LCK (mouse) that has been phosphorylated at the position equivalent to Tyr-192 of the amino acid sequence represented by UniProtKB:P06240. UniProtKB:P06240, Tyr-192, MOD:00048." [PMID:21183079, PRO:HJD]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:21183079). Evidence=(ECO:0006055, based on PMID:21183079).
synonym: "mLCK/Phos:3" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P06240, Tyr-192, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P06240 ! proto-oncogene tyrosine-protein kinase LCK (mouse)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000049824
name: proto-oncogene tyrosine-protein kinase LCK phosphorylated 2 (mouse)
def: "A proto-oncogene tyrosine-protein kinase LCK (mouse) that has been phosphorylated at the position equivalent to Ser-35 of the amino acid sequence represented by UniProtKB:P06240. UniProtKB:P06240, Ser-35, MOD:00046." [PMID:21183079, PRO:HJD]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:21183079). Evidence=(ECO:0006055, based on PMID:21183079).
synonym: "mLCK/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P06240, Ser-35, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P06240 ! proto-oncogene tyrosine-protein kinase LCK (mouse)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus