[Term]
id: PR:000002311
name: caspase-2
def: "A caspase-1-like protease that is a translation product of the human CASP2 gene or a 1:1 ortholog thereof. This protein is involved in the activation cascade of caspases responsible for apoptosis execution." [PRO:WCB]
comment: Category=gene.
synonym: "ICH1" RELATED Gene-based []
synonym: "CASP2" EXACT PRO-short-label [PRO:DNx]
synonym: "NEDD2" RELATED Gene-based []
synonym: "CASP-2" EXACT []
synonym: "NEDD-2" EXACT []
synonym: "protease ICH-1" EXACT []
synonym: "neural precursor cell expressed developmentally down-regulated protein 2" EXACT []
xref: IUPHARobj:1618
is_a: PR:000002195 ! caspase-1-like protease

[Term]
id: PR:P55215-2
name: caspase-2 isoform r2 (rat)
def: "A caspase-2 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55215-2." [PRO:DNx, UniProtKB:P55215]
comment: Category=organism-sequence.
synonym: "rCASP2/iso:r2" EXACT PRO-short-label [PRO:DNx]
synonym: "caspase-2 isoform caspase-2S (rat)" EXACT [UniProtKB:P55215]
xref: UniProtKB:P55215-2
is_a: PR:P55215 ! caspase-2 (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:P55215-1
name: caspase-2 isoform r1 (rat)
def: "A caspase-2 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55215-1." [PRO:DNx, UniProtKB:P55215]
comment: Category=organism-sequence.
synonym: "rCASP2/iso:r1" EXACT PRO-short-label [PRO:DNx]
synonym: "caspase-2 isoform caspase-2L (rat)" EXACT [UniProtKB:P55215]
xref: UniProtKB:P55215-1
is_a: PR:P55215 ! caspase-2 (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:P55215
name: caspase-2 (rat)
def: "A caspase-2 that is encoded in the genome of rat." [OMA:P55215, PANTHER:PTHR10454:SF21, PRO:DNx]
comment: Category=organism-gene.
synonym: "Ich1" RELATED Gene-based [UniProtKB:P55215]
synonym: "Casp2" RELATED Gene-based [UniProtKB:P55215]
synonym: "rCASP2" EXACT PRO-short-label [PRO:DNx]
synonym: "CASP-2 (rat)" EXACT [UniProtKB:P55215]
synonym: "protease ICH-1 (rat)" EXACT [UniProtKB:P55215]
xref: UniProtKB:P55215
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000002311 ! caspase-2
relationship: has_gene_template RGD:69274 ! Casp2 (rat)