[Term]
id: PR:Q9Y4K3-1
name: TNF receptor-associated factor 6 isoform 1 (human)
def: "A TNF receptor-associated factor 6 isoform 1 that is encoded in the genome of human." [PRO:JAN]
comment: Category=organism-sequence.
synonym: "hTRAF6/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9Y4K3-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002381 ! TNF receptor-associated factor 6 isoform 1

[Term]
id: PR:000035714
name: TNF receptor-associated factor 6 K63-polyubiquitinated 1 (human)
def: "A TNF receptor-associated factor 6 K63-polyubiquitinated 1 in human. UniProtKB:Q9Y4K3, Lys-124, PR:000044772." [PRO:DAN, UniProtKB:Q9Y4K3]
comment: Category=organism-modification.
synonym: "K63-pUb-TRAF6" RELATED []
synonym: "hTRAF6/K63polyUbiq:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9Y4K3, Lys-124, PR:000044772" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-450227 "PR:000035714 located_in GO:0010008"
xref: Reactome:R-HSA-936980 "PR:000035714 located_in GO:0005886"
xref: Reactome:R-HSA-2685681 "PR:000035714 located_in GO:0005829"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000035713 ! TNF receptor-associated factor 6 K63-polyubiquitinated 1
relationship: has_part PR:000044772 ! K63-polyubiquitinylated lysine

[Term]
id: PR:000002292
name: TNF receptor-associated factor 6
def: "A TNF receptor-associated factor that is a translation product of the human TRAF6 gene or a 1:1 ortholog thereof." [PRO:WCB]
comment: Category=gene.
synonym: "RNF85" RELATED Gene-based []
synonym: "TRAF6" EXACT PRO-short-label [PRO:DNx]
synonym: "RING finger protein 85" EXACT []
synonym: "interleukin-1 signal transducer" EXACT []
synonym: "E3 ubiquitin-protein ligase TRAF6" EXACT []
synonym: "RING-type E3 ubiquitin transferase TRAF6" EXACT []
is_a: PR:000002191 ! TNF receptor-associated factor

[Term]
id: PR:Q9Y4K3
name: TNF receptor-associated factor 6 (human)
def: "A TNF receptor-associated factor 6 that is encoded in the genome of human." [PRO:CNx, UniProtKB:Q9Y4K3]
comment: Category=organism-gene.
synonym: "RNF85" RELATED Gene-based [UniProtKB:Q9Y4K3]
synonym: "TRAF6" RELATED Gene-based [UniProtKB:Q9Y4K3]
synonym: "hTRAF6" EXACT PRO-short-label [PRO:DNx]
synonym: "RING finger protein 85 (human)" EXACT [UniProtKB:Q9Y4K3]
synonym: "interleukin-1 signal transducer (human)" EXACT [UniProtKB:Q9Y4K3]
synonym: "E3 ubiquitin-protein ligase TRAF6 (human)" EXACT [UniProtKB:Q9Y4K3]
synonym: "RING-type E3 ubiquitin transferase TRAF6 (human)" EXACT [UniProtKB:Q9Y4K3]
xref: UniProtKB:Q9Y4K3
xref: Reactome:R-HSA-166366 "PR:Q9Y4K3 located_in GO:0005829"
xref: Reactome:R-HSA-450272 "PR:Q9Y4K3 located_in GO:0010008"
xref: Reactome:R-HSA-936955 "PR:Q9Y4K3 located_in GO:0005886"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002292 ! TNF receptor-associated factor 6
relationship: has_gene_template HGNC:12036 ! TRAF6 (human)