[Term]
id: PR:000028382
name: TNF receptor-associated factor 2, initiator methionine removed form (human)
def: "A TNF receptor-associated factor 2, initiator methionine removed form in human. Example: UniProtKB:Q12933-1, 2-501." [PRO:DNx]
comment: Category=organism-modification.
synonym: "PRO_0000056399" NARROW PRO-proteoform-ftid [PRO:DNx]
synonym: "hTRAF2/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q12933-1, 2-501" NARROW PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-66370 "PR:000028382 located_in GO:0005829"
xref: Reactome:R-HSA-8862199 "PR:000028382 located_in GO:0005654"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000018757 ! TNF receptor-associated factor 2, initiator methionine removed form

[Term]
id: PR:Q12933-4
name: TNF receptor-associated factor 2 isoform h4 (human)
def: "A TNF receptor-associated factor 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q12933-4." [PRO:DNx, UniProtKB:Q12933]
comment: Category=organism-sequence.
synonym: "hTRAF2/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q12933-4
is_a: PR:Q12933 ! TNF receptor-associated factor 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q12933
name: TNF receptor-associated factor 2 (human)
def: "A TNF receptor-associated factor 2 that is encoded in the genome of human." [PRO:WCB, UniProtKB:Q12933]
comment: Category=organism-gene.
synonym: "TRAF2" RELATED Gene-based [UniProtKB:Q12933]
synonym: "TRAP3" RELATED Gene-based [UniProtKB:Q12933]
synonym: "hTRAF2" EXACT PRO-short-label [PRO:DNx]
synonym: "E3 ubiquitin-protein ligase TRAF2 (human)" EXACT [UniProtKB:Q12933]
synonym: "RING-type E3 ubiquitin transferase TRAF2 (human)" EXACT [UniProtKB:Q12933]
synonym: "tumor necrosis factor type 2 receptor-associated protein 3 (human)" EXACT [UniProtKB:Q12933]
xref: UniProtKB:Q12933
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002288 ! TNF receptor-associated factor 2
relationship: has_gene_template HGNC:12032 ! TRAF2 (human)

[Term]
id: PR:000049534
name: TNF receptor-associated factor 2, initiator methionine removed ubiquitinated form (human)
def: "A TNF receptor-associated factor 2, initiator methionine removed form (human) that includes at least one ubiquitinated lysine. UniProtKB:Q12933, 2-501, MOD:01148." [PRO:DNx, Reactome:R-HSA-8862194]
comment: Category=organism-modification.
synonym: "hTRAF2/InitMet-/UbiqLys+" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000056399, MOD:01148" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:Q12933, 2-501, MOD:01148" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-8862194 "PR:000049534 located_in GO:0005654"
intersection_of: has_part MOD:01148 ! ubiquitinylated lysine
intersection_of: PR:000028382 ! TNF receptor-associated factor 2, initiator methionine removed form (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000002288
name: TNF receptor-associated factor 2
def: "A TNF receptor-associated factor that is a translation product of the human TRAF2 gene or a 1:1 ortholog thereof." [PRO:WCB]
comment: Category=gene.
synonym: "TRAF2" EXACT PRO-short-label [PRO:DNx]
synonym: "TRAP3" RELATED Gene-based []
synonym: "E3 ubiquitin-protein ligase TRAF2" EXACT []
synonym: "RING-type E3 ubiquitin transferase TRAF2" EXACT []
synonym: "tumor necrosis factor type 2 receptor-associated protein 3" EXACT []
is_a: PR:000002191 ! TNF receptor-associated factor

[Term]
id: PR:Q12933-2
name: TNF receptor-associated factor 2 isoform 2 (human)
def: "A TNF receptor-associated factor 2 isoform 3 that is encoded in the genome of human." [PRO:JAN]
comment: Category=organism-sequence.
synonym: "hTRAF2/iso:2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q12933-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002376 ! TNF receptor-associated factor 2 isoform 3

[Term]
id: PR:Q12933-1
name: TNF receptor-associated factor 2 isoform 1 (human)
def: "A TNF receptor-associated factor 2 isoform 1 that is encoded in the genome of human." [PRO:JAN]
comment: Category=organism-sequence.
synonym: "hTRAF2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q12933-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002374 ! TNF receptor-associated factor 2 isoform 1

[Term]
id: PR:Q12933-3
name: TNF receptor-associated factor 2 isoform h3 (human)
def: "A TNF receptor-associated factor 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q12933-3." [PRO:DNx, UniProtKB:Q12933]
comment: Category=organism-sequence.
synonym: "hTRAF2/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q12933-3
is_a: PR:Q12933 ! TNF receptor-associated factor 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045896
name: TNF receptor-associated factor 2 phosphorylated 1 (human)
def: "A TNF receptor-associated factor 2 (human) that has been phosphorylated at the position equivalent to Ser-55 of the amino acid sequence represented by UniProtKB:Q12933-1. Example: UniProtKB:Q12933-1, Ser-55, MOD:00046." [PMID:19336568, iPTMnet:Q12933]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:19336568). Status=unreviewed.
synonym: "hTRAF2/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q12933-1, Ser-55, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q12933 ! TNF receptor-associated factor 2 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens