[Term]
id: PR:O35732
name: CASP8 and FADD-like apoptosis regulator (mouse)
def: "A CASP8 and FADD-like apoptosis regulator that is encoded in the genome of mouse." [OMA:O35732, PRO:DNx]
comment: Category=organism-gene.
synonym: "Cash" RELATED Gene-based [UniProtKB:O35732]
synonym: "Cflar" RELATED Gene-based [UniProtKB:O35732]
synonym: "mCFLAR" EXACT PRO-short-label [PRO:DNx]
synonym: "CASH (mouse)" EXACT [UniProtKB:O35732]
synonym: "MRIT (mouse)" EXACT [UniProtKB:O35732]
synonym: "CLARP (mouse)" EXACT [UniProtKB:O35732]
synonym: "c-FLIP (mouse)" EXACT [UniProtKB:O35732]
synonym: "casper (mouse)" EXACT [UniProtKB:O35732]
synonym: "FLAME-1 (mouse)" EXACT [UniProtKB:O35732]
synonym: "I-FLICE (mouse)" EXACT [UniProtKB:O35732]
synonym: "usurpin (mouse)" EXACT [UniProtKB:O35732]
synonym: "caspase homolog (mouse)" EXACT [UniProtKB:O35732]
synonym: "inhibitor of FLICE (mouse)" EXACT [UniProtKB:O35732]
synonym: "caspase-eight-related protein (mouse)" EXACT [UniProtKB:O35732]
synonym: "MACH-related inducer of toxicity (mouse)" EXACT [UniProtKB:O35732]
synonym: "FADD-like antiapoptotic molecule 1 (mouse)" EXACT [UniProtKB:O35732]
synonym: "cellular FLICE-like inhibitory protein (mouse)" EXACT [UniProtKB:O35732]
synonym: "caspase-like apoptosis regulatory protein (mouse)" EXACT [UniProtKB:O35732]
xref: UniProtKB:O35732
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000002282 ! CASP8 and FADD-like apoptosis regulator
relationship: has_gene_template MGI:1336166 ! Cflar (mouse)

[Term]
id: PR:O35732-1
name: CASP8 and FADD-like apoptosis regulator isoform m1 (mouse)
def: "A CASP8 and FADD-like apoptosis regulator (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O35732-1." [PRO:DNx, UniProtKB:O35732]
comment: Category=organism-sequence.
synonym: "mCFLAR/iso:m1" EXACT PRO-short-label [PRO:DNx]
synonym: "CASP8 and FADD-like apoptosis regulator isoform FLIP-L (mouse)" EXACT [UniProtKB:O35732]
synonym: "CASP8 and FADD-like apoptosis regulator isoform CASH alpha (mouse)" EXACT [UniProtKB:O35732]
xref: UniProtKB:O35732-1
is_a: PR:O35732 ! CASP8 and FADD-like apoptosis regulator (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:O35732-2
name: CASP8 and FADD-like apoptosis regulator isoform m2 (mouse)
def: "A CASP8 and FADD-like apoptosis regulator (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O35732-2." [PRO:DNx, UniProtKB:O35732]
comment: Category=organism-sequence.
synonym: "mCFLAR/iso:m2" EXACT PRO-short-label [PRO:DNx]
synonym: "CASP8 and FADD-like apoptosis regulator isoform FLIP-S (mouse)" EXACT [UniProtKB:O35732]
synonym: "CASP8 and FADD-like apoptosis regulator isoform CASH beta (mouse)" EXACT [UniProtKB:O35732]
xref: UniProtKB:O35732-2
is_a: PR:O35732 ! CASP8 and FADD-like apoptosis regulator (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000002282
name: CASP8 and FADD-like apoptosis regulator
def: "A caspase-8-like protease that is a translation product of the human CFLAR gene or a 1:1 ortholog thereof." [PRO:WCB]
comment: Category=gene.
synonym: "CASH" RELATED Gene-based []
synonym: "MRIT" RELATED Gene-based []
synonym: "CFLAR" EXACT PRO-short-label [PRO:DNx]
synonym: "CLARP" RELATED Gene-based []
synonym: "c-FLIP" EXACT []
synonym: "casper" EXACT []
synonym: "FLAME-1" EXACT []
synonym: "I-FLICE" EXACT []
synonym: "usurpin" EXACT []
synonym: "CASP8AP1" RELATED Gene-based []
synonym: "caspase homolog" EXACT []
synonym: "inhibitor of FLICE" EXACT []
synonym: "caspase-eight-related protein" EXACT []
synonym: "MACH-related inducer of toxicity" EXACT []
synonym: "FADD-like antiapoptotic molecule 1" EXACT []
synonym: "cellular FLICE-like inhibitory protein" EXACT []
synonym: "caspase-like apoptosis regulatory protein" EXACT []
is_a: PR:000002197 ! caspase-8-like protease