[Term]
id: PR:P06396-3
name: gelsolin isoform h3 (human)
def: "A gelsolin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P06396-3." [PRO:DNx, UniProtKB:P06396]
comment: Category=organism-sequence.
synonym: "hGSN/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P06396-3
is_a: PR:P06396 ! gelsolin (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000047636
name: gelsolin, signal peptide removed form (human)
def: "A gelsolin (human) that has had the signal peptide removed. UniProtKB:P06396, 28-782." [PRO:DNx, Reactome:R-HSA-350275]
comment: Category=organism-modification.
synonym: "hGSN/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000036385" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P06396, 28-782" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-350275 "PR:000047636 located_in GO:0005829"
xref: Reactome:R-HSA-6801465 "PR:000047636 located_in GO:1904813"
xref: Reactome:R-HSA-6801486 "PR:000047636 located_in GO:0034774"
xref: Reactome:R-HSA-6806510 "PR:000047636 located_in GO:0005576"
intersection_of: PR:P06396 ! gelsolin (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000002202
name: gelsolin
def: "A protein that is a translation product of the human GSN gene or a 1:1 ortholog thereof." [PRO:WCB]
comment: Category=gene.
synonym: "ADF" RELATED []
synonym: "GSN" EXACT PRO-short-label [PRO:DNx]
synonym: "Gsb" RELATED Gene-based []
synonym: "AGEL" EXACT []
synonym: "brevin" EXACT []
synonym: "actin-depolymerizing factor" RELATED []
is_a: PR:000000001 ! protein

[Term]
id: PR:P06396-4
name: gelsolin isoform h4 (human)
def: "A gelsolin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P06396-4." [PRO:DNx, UniProtKB:P06396]
comment: Category=organism-sequence.
synonym: "hGSN/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P06396-4
is_a: PR:P06396 ! gelsolin (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000053585
name: gelsolin O-glycosylated 8 (human)
def: "A gelsolin (human) that has been O-glycosylated at the residue equivalent to Ser-412 of the amino acid sequence represented by UniProtKB:P06396-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P06396-1, Ser-412, MOD:00002~GNO:G43417UB." [GlyGen:P06396-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hGSN/OGlyco:8" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P06396-1, Ser-412, MOD:00002~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P06396 ! gelsolin (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00002 ! O-glycosyl-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P06396-2
name: gelsolin isoform 2 (human)
def: "A gelsolin isoform 2 that is encoded in the genome of human." [PRO:JAN]
comment: Category=organism-sequence.
synonym: "hGSN/iso:2" EXACT PRO-short-label [PRO:DNx]
synonym: "gelsolin isoform Cytoplasmic (human)" EXACT [UniProtKB:P06396]
xref: UniProtKB:P06396-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002328 ! gelsolin isoform 2

[Term]
id: PR:P06396
name: gelsolin (human)
def: "A gelsolin that is encoded in the genome of human." [PRO:WCB, UniProtKB:P06396]
comment: Category=organism-gene.
synonym: "GSN" RELATED Gene-based [UniProtKB:P06396]
synonym: "hGSN" EXACT PRO-short-label [PRO:DNx]
synonym: "ADF (human)" BROAD [UniProtKB:P06396]
synonym: "AGEL (human)" EXACT [UniProtKB:P06396]
synonym: "brevin (human)" EXACT [UniProtKB:P06396]
synonym: "actin-depolymerizing factor (human)" BROAD [UniProtKB:P06396]
xref: UniProtKB:P06396
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002202 ! gelsolin
relationship: has_gene_template HGNC:4620 ! GSN (human)

[Term]
id: PR:000053584
name: gelsolin O-glycosylated 7 (human)
def: "A gelsolin (human) that has been O-glycosylated at the residue equivalent to Ser-412 of the amino acid sequence represented by UniProtKB:P06396-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P06396-1, Ser-412, MOD:00002~GNO:G29068FM." [GlyGen:P06396-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hGSN/OGlyco:7" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P06396-1, Ser-412, MOD:00002~GNO:G29068FM" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P06396 ! gelsolin (human)
relationship: has_part GNO:G29068FM ! G29068FM
relationship: has_part MOD:00002 ! O-glycosyl-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000053589
name: gelsolin O-glycosylated 12 (human)
def: "A gelsolin (human) that has been O-glycosylated at the residue equivalent to Thr-431 of the amino acid sequence represented by UniProtKB:P06396-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P06396-1, Thr-431, MOD:00005~GNO:G43417UB." [GlyGen:P06396-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hGSN/OGlyco:12" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P06396-1, Thr-431, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P06396 ! gelsolin (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000053588
name: gelsolin O-glycosylated 11 (human)
def: "A gelsolin (human) that has been O-glycosylated at the residue equivalent to Thr-426 of the amino acid sequence represented by UniProtKB:P06396-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P06396-1, Thr-426, MOD:00005~GNO:G43417UB." [GlyGen:P06396-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hGSN/OGlyco:11" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P06396-1, Thr-426, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P06396 ! gelsolin (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P06396-1
name: gelsolin isoform 1 (human)
def: "A gelsolin isoform 1 that is encoded in the genome of human." [PRO:JAN]
comment: Category=organism-sequence.
synonym: "hGSN/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "gelsolin isoform Plasma (human)" EXACT [UniProtKB:P06396]
synonym: "gelsolin isoform Secreted (human)" EXACT [UniProtKB:P06396]
xref: UniProtKB:P06396-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002327 ! gelsolin isoform 1

[Term]
id: PR:000053581
name: gelsolin O-glycosylated 4 (human)
def: "A gelsolin (human) that has been O-glycosylated at the residue equivalent to Ser-411 of the amino acid sequence represented by UniProtKB:P06396-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P06396-1, Ser-411, MOD:00002~GNO:G29068FM." [GlyGen:P06396-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hGSN/OGlyco:4" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P06396-1, Ser-411, MOD:00002~GNO:G29068FM" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P06396 ! gelsolin (human)
relationship: has_part GNO:G29068FM ! G29068FM
relationship: has_part MOD:00002 ! O-glycosyl-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000053580
name: gelsolin O-glycosylated 3 (human)
def: "A gelsolin (human) that has been O-glycosylated at the residue equivalent to Ser-408 of the amino acid sequence represented by UniProtKB:P06396-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P06396-1, Ser-408, MOD:00002~GNO:G43417UB." [GlyGen:P06396-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hGSN/OGlyco:3" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P06396-1, Ser-408, MOD:00002~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P06396 ! gelsolin (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00002 ! O-glycosyl-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000053583
name: gelsolin O-glycosylated 6 (human)
def: "A gelsolin (human) that has been O-glycosylated at the residue equivalent to Ser-411 of the amino acid sequence represented by UniProtKB:P06396-1, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:P06396-1, Ser-411, MOD:00002~GNO:G53434XO." [GlyGen:P06396-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hGSN/OGlyco:6" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P06396-1, Ser-411, MOD:00002~GNO:G53434XO" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P06396 ! gelsolin (human)
relationship: has_part GNO:G53434XO ! G53434XO
relationship: has_part MOD:00002 ! O-glycosyl-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000053582
name: gelsolin O-glycosylated 5 (human)
def: "A gelsolin (human) that has been O-glycosylated at the residue equivalent to Ser-411 of the amino acid sequence represented by UniProtKB:P06396-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P06396-1, Ser-411, MOD:00002~GNO:G43417UB." [GlyGen:P06396-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hGSN/OGlyco:5" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P06396-1, Ser-411, MOD:00002~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P06396 ! gelsolin (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00002 ! O-glycosyl-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000053578
name: gelsolin O-glycosylated 1 (human)
def: "A gelsolin (human) that has been O-glycosylated at the residue equivalent to Ser-31 of the amino acid sequence represented by UniProtKB:P06396-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P06396-1, Ser-31, MOD:00002~GNO:G43417UB." [GlyGen:P06396-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hGSN/OGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P06396-1, Ser-31, MOD:00002~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P06396 ! gelsolin (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00002 ! O-glycosyl-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000053579
name: gelsolin O-glycosylated 2 (human)
def: "A gelsolin (human) that has been O-glycosylated at the residue equivalent to Ser-408 of the amino acid sequence represented by UniProtKB:P06396-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P06396-1, Ser-408, MOD:00002~GNO:G29068FM." [GlyGen:P06396-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hGSN/OGlyco:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P06396-1, Ser-408, MOD:00002~GNO:G29068FM" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P06396 ! gelsolin (human)
relationship: has_part GNO:G29068FM ! G29068FM
relationship: has_part MOD:00002 ! O-glycosyl-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000053587
name: gelsolin O-glycosylated 10 (human)
def: "A gelsolin (human) that has been O-glycosylated at the residue equivalent to Thr-402 of the amino acid sequence represented by UniProtKB:P06396-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P06396-1, Thr-402, MOD:00005~GNO:G43417UB." [GlyGen:P06396-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hGSN/OGlyco:10" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P06396-1, Thr-402, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P06396 ! gelsolin (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000053586
name: gelsolin O-glycosylated 9 (human)
def: "A gelsolin (human) that has been O-glycosylated at the residue equivalent to Ser-430 of the amino acid sequence represented by UniProtKB:P06396-1, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:P06396-1, Ser-430, MOD:00002~GNO:G53434XO." [GlyGen:P06396-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hGSN/OGlyco:9" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P06396-1, Ser-430, MOD:00002~GNO:G53434XO" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P06396 ! gelsolin (human)
relationship: has_part GNO:G53434XO ! G53434XO
relationship: has_part MOD:00002 ! O-glycosyl-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens