[Term]
id: PR:O00220
name: tumor necrosis factor receptor superfamily member 10A (human)
def: "A tumor necrosis factor receptor superfamily member 10A that is encoded in the genome of human." [PRO:WCB, UniProtKB:O00220]
comment: Category=organism-gene.
synonym: "DR4" RELATED Gene-based [UniProtKB:O00220]
synonym: "APO2" RELATED Gene-based [UniProtKB:O00220]
synonym: "TRAILR1" RELATED Gene-based [UniProtKB:O00220]
synonym: "TNFRSF10A" RELATED Gene-based [UniProtKB:O00220]
synonym: "hTNFRSF10A" EXACT PRO-short-label [PRO:DNx]
synonym: "CD261 (human)" EXACT [UniProtKB:O00220]
synonym: "TRAIL-R1 (human)" EXACT [UniProtKB:O00220]
synonym: "TRAIL receptor 1 (human)" EXACT [UniProtKB:O00220]
synonym: "death receptor 4 (human)" EXACT [UniProtKB:O00220]
synonym: "TNF-related apoptosis-inducing ligand receptor 1 (human)" EXACT [UniProtKB:O00220]
xref: UniProtKB:O00220
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002108 ! tumor necrosis factor receptor superfamily member 10A
relationship: has_gene_template HGNC:11904 ! TNFRSF10A (human)

[Term]
id: PR:000050628
name: tumor necrosis factor receptor superfamily member 10A O-glycosylated 1 (human)
def: "A tumor necrosis factor receptor superfamily member 10A (human) that has been O-glycosylated at the residue equivalent to Ser-126 of the amino acid sequence represented by UniProtKB:O00220-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:O00220-1, Ser-126, MOD:00002~GNO:G43417UB." [GlyGen:O00220-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hTNFRSF10A/OGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O00220-1, Ser-126, MOD:00002~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:O00220 ! tumor necrosis factor receptor superfamily member 10A (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00002 ! O-glycosyl-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O00220-1
name: tumor necrosis factor receptor superfamily member 10A isoform 1 (human)
def: "A tumor necrosis factor receptor superfamily member 10A isoform 1 that is encoded in the genome of human." [PRO:JAN]
comment: Category=organism-sequence.
synonym: "hTNFRSF10A/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O00220-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002225 ! tumor necrosis factor receptor superfamily member 10A isoform 1

[Term]
id: PR:000049485
name: tumor necrosis factor receptor superfamily member 10A, signal peptide removed form (human)
def: "A tumor necrosis factor receptor superfamily member 10A (human) that has had the signal peptide removed. UniProtKB:O00220, 24-468." [PRO:DNx, Reactome:R-HSA-5633393]
comment: Category=organism-modification.
synonym: "PRO_0000034579" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hTNFRSF10A/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O00220, 24-468" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5633393 "PR:000049485 located_in GO:0005886"
intersection_of: PR:O00220 ! tumor necrosis factor receptor superfamily member 10A (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000002108
name: tumor necrosis factor receptor superfamily member 10A
def: "A tumor necrosis factor receptor superfamily member 10A/B that is a translation product of the human TNFRSF10A gene or a 1:1 ortholog thereof. No mouse gene has been assigned this name." [PRO:WCB]
comment: Category=gene.
synonym: "DR4" RELATED Gene-based []
synonym: "APO2" RELATED Gene-based []
synonym: "CD261" EXACT []
synonym: "TRAILR1" RELATED Gene-based []
synonym: "TRAIL-R1" EXACT []
synonym: "TNFRSF10A" EXACT PRO-short-label [PRO:DNx]
synonym: "TRAIL receptor 1" EXACT []
synonym: "death receptor 4" EXACT []
synonym: "TNF-related apoptosis-inducing ligand receptor 1" EXACT []
xref: IUPHARobj:1879
is_a: PR:000001951 ! tumor necrosis factor receptor superfamily member 10A/B