[Term]
id: PR:000049366
name: signal transducer and activator of transcription 6 phosphorylated 2 (human)
def: "A signal transducer and activator of transcription 6 (human) that has been post-translationally modified to include phosphoserine at position 407 of the amino acid sequence represented by UniProtKB:P42226. UniProtKB:P42226, Ser-407, MOD:00046." [PRO:DNx, Reactome:R-HSA-3249369]
comment: Category=organism-modification.
synonym: "hSTAT6/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P42226, Ser-407, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-3249369 "PR:000049366 located_in GO:0005829"
is_a: PR:P42226 ! signal transducer and activator of transcription 6 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000049367
name: signal transducer and activator of transcription 6 phosphorylated 3 (human)
def: "A signal transducer and activator of transcription 6 (human) that has been post-translationally modified to include phosphoserine at position 407, and phosphotyrosine at position 641 of the amino acid sequence represented by UniProtKB:P42226. UniProtKB:P42226, Ser-407, MOD:00046|Tyr-641, MOD:00048." [PRO:DNx, Reactome:R-HSA-3249376, Reactome:R-HSA-3261241]
comment: Category=organism-modification.
synonym: "hSTAT6/Phos:3" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P42226, Ser-407, MOD:00046|Tyr-641, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-3249376 "PR:000049367 located_in GO:0005829"
xref: Reactome:R-HSA-3261241 "PR:000049367 located_in GO:0005654"
is_a: PR:P42226 ! signal transducer and activator of transcription 6 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000002093
name: signal transducer and activator of transcription 6
def: "A signal transducer and transcription activator STAT that is a translation product of the human STAT6 gene or a 1:1 ortholog thereof." [PRO:WCB]
comment: Category=gene.
synonym: "STAT6" EXACT PRO-short-label [PRO:DNx]
synonym: "IL-4 Stat" EXACT []
is_a: PR:000001933 ! signal transducer and transcription activator STAT

[Term]
id: PR:P42226
name: signal transducer and activator of transcription 6 (human)
def: "A signal transducer and activator of transcription 6 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P42226]
comment: Category=organism-gene.
synonym: "STAT6" RELATED Gene-based [UniProtKB:P42226]
synonym: "hSTAT6" EXACT PRO-short-label [PRO:DNx]
synonym: "IL-4 Stat (human)" EXACT [UniProtKB:P42226]
xref: Reactome:R-HSA-629625 "PR:P42226 located_in GO:0005829"
xref: UniProtKB:P42226
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002093 ! signal transducer and activator of transcription 6
relationship: has_gene_template HGNC:11368 ! STAT6 (human)

[Term]
id: PR:P42226-1
name: signal transducer and activator of transcription 6 isoform h1 (human)
def: "A signal transducer and activator of transcription 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P42226-1." [PRO:DNx, UniProtKB:P42226]
comment: Category=organism-sequence.
synonym: "hSTAT6/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P42226-1
is_a: PR:P42226 ! signal transducer and activator of transcription 6 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045778
name: signal transducer and activator of transcription 6 phosphorylated 1 (human)
def: "A signal transducer and activator of transcription 6 (human) that has been phosphorylated at the position equivalent to Ser-707 of the amino acid sequence represented by UniProtKB:P42226-1. Example: UniProtKB:P42226-1, Ser-707, MOD:00046." [PMID:21123173, iPTMnet:P42226]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:21123173). Status=unreviewed.
synonym: "hSTAT6/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P42226-1, Ser-707, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P42226 ! signal transducer and activator of transcription 6 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P42226-2
name: signal transducer and activator of transcription 6 isoform h2 (human)
def: "A signal transducer and activator of transcription 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P42226-2." [PRO:DNx, UniProtKB:P42226]
comment: Category=organism-sequence.
synonym: "hSTAT6/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P42226-2
is_a: PR:P42226 ! signal transducer and activator of transcription 6 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P42226-3
name: signal transducer and activator of transcription 6 isoform h3 (human)
def: "A signal transducer and activator of transcription 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P42226-3." [PRO:DNx, UniProtKB:P42226]
comment: Category=organism-sequence.
synonym: "hSTAT6/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P42226-3
is_a: PR:P42226 ! signal transducer and activator of transcription 6 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens