[Term]
id: PR:000037009
name: signal transducer and activator of transcription 3 isoform Stat3A phosphorylated 1 (mouse)
def: "A signal transducer and activator of transcription 3 isoform Stat3A (mouse) that has been phosphorylated on a residue equivalent to UniProtKB:P42227-1 Tyr-705. UniProtKB:P42227-1, Tyr-705, MOD:00048." [PMID:26026268, PRO:HJD]
comment: Category=organism-modification.
synonym: "mSTAT3/iso:Stat3A/Phos:1" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P42227-1, Tyr-705, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P42227-1 ! signal transducer and activator of transcription 3 isoform Stat3A (mouse)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000002089
name: signal transducer and activator of transcription 3
def: "A signal transducer and transcription activator STAT that is a translation product of the human STAT3 gene or a 1:1 ortholog thereof." [PRO:WCB]
comment: Category=gene.
synonym: "APRF" RELATED Gene-based []
synonym: "STAT3" EXACT PRO-short-label [PRO:DNx]
synonym: "acute-phase response factor" EXACT []
is_a: PR:000001933 ! signal transducer and transcription activator STAT

[Term]
id: PR:P42227-1
name: signal transducer and activator of transcription 3 isoform Stat3A (mouse)
def: "A signal transducer and activator of transcription 3 isoform 1 that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:P42227]
comment: Category=organism-sequence.
synonym: "mSTAT3/iso:Stat3A" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P42227-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000027921 ! signal transducer and activator of transcription 3 isoform 1

[Term]
id: PR:P42227
name: signal transducer and activator of transcription 3 (mouse)
def: "A signal transducer and activator of transcription 3 that is encoded in the genome of mouse." [OMA:P42227, PRO:DNx]
comment: Category=organism-gene.
synonym: "Aprf" RELATED Gene-based [UniProtKB:P42227]
synonym: "Stat3" RELATED Gene-based [UniProtKB:P42227]
synonym: "mSTAT3" EXACT PRO-short-label [PRO:DNx]
synonym: "acute-phase response factor (mouse)" EXACT [UniProtKB:P42227]
xref: UniProtKB:P42227
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000002089 ! signal transducer and activator of transcription 3
relationship: has_gene_template MGI:103038 ! Stat3 (mouse)

[Term]
id: PR:000045779
name: signal transducer and activator of transcription 3 isoform Stat3A phosphorylated 2 (mouse)
def: "A signal transducer and activator of transcription 3 isoform Stat3A (mouse) that has been phosphorylated at Ser-727 of the amino acid sequence represented by UniProtKB:P42227-1. UniProtKB:P42227-1, Ser-727, MOD:00046." [PMID:14617800, PMID:15096606, PRO:CNA, iPTMnet:P42227]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:14617800, PMID:15096606).
synonym: "mSTAT3/iso:Stat3A/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P42227-1, Ser-727, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P42227-1 ! signal transducer and activator of transcription 3 isoform Stat3A (mouse)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000049779
name: signal transducer and activator of transcription 3 isoform Stat3A unphosphorylated 2 (mouse)
def: "A signal transducer and activator of transcription 3 isoform Stat3A (mouse) that is unphosphorylated at the position equivalent to Ser-727. UniProtKB:P42227-1, Ser-727, PR:000026291." [PMID:26764350, PRO:HJD]
comment: Category=organism-modification.
synonym: "mSTAT3/iso:Stat3A/UnPhos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P42227-1, Ser-727, PR:000026291" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P42227-1 ! signal transducer and activator of transcription 3 isoform Stat3A (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000049778
name: signal transducer and activator of transcription 3 isoform Stat3A unphosphorylated 1 (mouse)
def: "A signal transducer and activator of transcription 3 isoform Stat3A (mouse) that lacks phosphorylation at position Tyr-705. UniProtKB:P42227-1, Tyr-705, PR:000026291." [PMID:26764350, PRO:HJD]
comment: Category=organism-modification.
synonym: "mSTAT3/iso:Stat3A/UnPhos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P42227-1, Tyr-705, PR:000026291" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P42227-1 ! signal transducer and activator of transcription 3 isoform Stat3A (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P42227-3
name: signal transducer and activator of transcription 3 isoform Del-701 (mouse)
def: "A signal transducer and activator of transcription 3 isoform Del-701 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mSTAT3/iso:Del-701" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P42227-3
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000039402 ! signal transducer and activator of transcription 3 isoform Del-701

[Term]
id: PR:P42227-2
name: signal transducer and activator of transcription 3 isoform mStat3B (mouse)
def: "A signal transducer and activator of transcription 3 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P42227-2." [PRO:DNx, UniProtKB:P42227]
comment: Category=organism-sequence.
synonym: "mSTAT3/iso:mStat3B" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P42227-2
is_a: PR:P42227 ! signal transducer and activator of transcription 3 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus