[Term] id: PR:000002064 name: macrosialin def: "A lysosome-associated membrane protein that is a translation product of the human CD68 gene or a 1:1 ortholog thereof." [PRO:WCB] comment: Category=gene. Requested by=CL. synonym: "CD68" EXACT PRO-short-label [PRO:DNx] synonym: "gp110" RELATED [] is_a: PR:000001883 ! lysosome-associated membrane protein [Term] id: PR:000056380 name: macrosialin O-glycosylated 1 (human) def: "A macrosialin (human) that has been O-glycosylated at the residue equivalent to Ser-137 of the amino acid sequence represented by UniProtKB:P34810-1, in which the glycan composition is represented by GlyTouCan:G88713AC. Example: UniProtKB:P34810-1, Ser-137, MOD:00002~GNO:G88713AC." [GlyGen:P34810-1, PMID:30459171, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hCD68/OGlyco:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P34810-1, Ser-137, MOD:00002~GNO:G88713AC" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P34810 ! macrosialin (human) relationship: has_part GNO:G88713AC ! G88713AC relationship: has_part MOD:00002 ! O-glycosyl-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P34810 name: macrosialin (human) def: "A macrosialin that is encoded in the genome of human." [PRO:WCB, UniProtKB:P34810] comment: Category=organism-gene. synonym: "CD68" RELATED Gene-based [UniProtKB:P34810] synonym: "hCD68" EXACT PRO-short-label [PRO:DNx] synonym: "gp110 (human)" BROAD [UniProtKB:P34810] xref: UniProtKB:P34810 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000002064 ! macrosialin relationship: has_gene_template HGNC:1693 ! CD68 (human) [Term] id: PR:P34810-1 name: macrosialin isoform Long (human) def: "A macrosialin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P34810-1." [PRO:DNx, UniProtKB:P34810] comment: Category=organism-sequence. synonym: "hCD68/iso:Long" EXACT PRO-short-label [PRO:DNx] synonym: "macrosialin isoform CD68.1 (human)" EXACT [UniProtKB:P34810] xref: UniProtKB:P34810-1 is_a: PR:P34810 ! macrosialin (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P34810-2 name: macrosialin isoform Short (human) def: "A macrosialin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P34810-2." [PRO:DNx, UniProtKB:P34810] comment: Category=organism-sequence. synonym: "hCD68/iso:Short" EXACT PRO-short-label [PRO:DNx] synonym: "macrosialin isoform CD68.2 (human)" EXACT [UniProtKB:P34810] xref: UniProtKB:P34810-2 is_a: PR:P34810 ! macrosialin (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P34810-3 name: macrosialin isoform h3 (human) def: "A macrosialin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P34810-3." [PRO:DNx, UniProtKB:P34810] comment: Category=organism-sequence. synonym: "hCD68/iso:h3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P34810-3 is_a: PR:P34810 ! macrosialin (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens