[Term] id: PR:000048049 name: interferon regulatory factor 7 phosphorylated 1 (human) def: "An interferon regulatory factor 7 (human) that has been post-translationally modified to include phosphoserine at positions 477 and 479 of the amino acid sequence represented by UniProtKB:Q92985. UniProtKB:Q92985, Ser-477/Ser-479, MOD:00046." [PRO:DNx, Reactome:R-HSA-450270, Reactome:R-HSA-450318] comment: Category=organism-modification. synonym: "hIRF7/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q92985, Ser-477/Ser-479, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-450270 "PR:000048049 located_in GO:0005654" xref: Reactome:R-HSA-450318 "PR:000048049 located_in GO:0005829" is_a: PR:Q92985 ! interferon regulatory factor 7 (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q92985-3 name: interferon regulatory factor 7 isoform C (human) def: "An interferon regulatory factor 7 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q92985-3." [PRO:DNx, UniProtKB:Q92985] comment: Category=organism-sequence. synonym: "hIRF7/iso:C" EXACT PRO-short-label [PRO:DNx] synonym: "interferon regulatory factor 7 isoform Gamma (human)" EXACT [UniProtKB:Q92985] xref: UniProtKB:Q92985-3 is_a: PR:Q92985 ! interferon regulatory factor 7 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000002049 name: interferon regulatory factor 7 def: "An interferon regulatory factor 3-9 that is a translation product of the human IRF7 gene or a 1:1 ortholog thereof." [PRO:WCB] comment: Category=gene. synonym: "IRF7" EXACT PRO-short-label [PRO:DNx] synonym: "IRF-7" EXACT [] is_a: PR:000001863 ! interferon regulatory factor 3-9 [Term] id: PR:Q92985-1 name: interferon regulatory factor 7 isoform A (human) def: "An interferon regulatory factor 7 isoform 1 that is encoded in the genome of human." [PRO:CNA] comment: Category=organism-sequence. synonym: "hIRF7/iso:A" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q92985-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000003261 ! interferon regulatory factor 7 isoform 1 [Term] id: PR:000048050 name: interferon regulatory factor 7 ubiquitinated form (human) def: "An interferon regulatory factor 7 (human) that includes at least one ubiquitinated lysine. UniProtKB:Q92985, MOD:01148." [PRO:DNx, Reactome:R-HSA-975154] comment: Category=organism-modification. synonym: "hIRF7/UbiqLys+" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q92985, MOD:01148" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-975154 "PR:000048050 located_in GO:0010008" intersection_of: has_part MOD:01148 ! ubiquitinylated lysine intersection_of: PR:Q92985 ! interferon regulatory factor 7 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000027082 name: interferon regulatory factor 7 isoform 1 phosphorylated 1 (human) def: "An interferon regulatory factor 7 isoform 1 phosphorylated 1 in human. UniProtKB:Q92985-1, Ser-477/Ser-479, MOD:00046." [PMID:10893229, PMID:14517278, TLR:AMM] comment: Category=organism-modification. Requested by=TLR. synonym: "hIRF7/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "phospho IRF7 (human)" EXACT [] synonym: "IRF-7 active form (human)" EXACT [] synonym: "IRF-7 phosphorylated (human)" EXACT [] synonym: "UniProtKB:Q92985-1, Ser-477/Ser-479, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000003281 ! interferon regulatory factor 7 isoform 1 phosphorylated 1 relationship: has_part MOD:00046 ! O-phospho-L-serine [Term] id: PR:Q92985-2 name: interferon regulatory factor 7 isoform B (human) def: "An interferon regulatory factor 7 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q92985-2." [PRO:DNx, UniProtKB:Q92985] comment: Category=organism-sequence. synonym: "hIRF7/iso:B" EXACT PRO-short-label [PRO:DNx] synonym: "interferon regulatory factor 7 isoform Beta (human)" EXACT [UniProtKB:Q92985] xref: UniProtKB:Q92985-2 is_a: PR:Q92985 ! interferon regulatory factor 7 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000037791 name: interferon regulatory factor 7 isoform 1 unphosphorylated 1 (human) def: "An interferon regulatory factor 7 isoform 1 unphosphorylated 1 in human. UniProtKB:Q92985-1, Ser-477/Ser-479, PR:000026291." [PMID:10893229, PMID:14517278, PRO:CNA] comment: Category=organism-modification. Requested by=TLR. synonym: "hIRF7/iso:1/UnPhos:1" EXACT PRO-short-label [PRO:DNx] synonym: "IRF-7 unphosphorylated (human)" RELATED [] synonym: "UniProtKB:Q92985-1, Ser-477/Ser-479, PR:000026291" EXACT PRO-proteoform-std [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000037790 ! interferon regulatory factor 7 isoform 1 unphosphorylated 1 [Term] id: PR:Q92985-4 name: interferon regulatory factor 7 isoform D (human) def: "An interferon regulatory factor 7 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q92985-4." [PRO:DNx, UniProtKB:Q92985] comment: Category=organism-sequence. synonym: "hIRF7/iso:D" EXACT PRO-short-label [PRO:DNx] synonym: "interferon regulatory factor 7 isoform H (human)" EXACT [UniProtKB:Q92985] xref: UniProtKB:Q92985-4 is_a: PR:Q92985 ! interferon regulatory factor 7 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q92985 name: interferon regulatory factor 7 (human) def: "An interferon regulatory factor 7 that is encoded in the genome of human." [PRO:WCB, UniProtKB:Q92985] comment: Category=organism-gene. synonym: "IRF7" RELATED Gene-based [UniProtKB:Q92985] synonym: "hIRF7" EXACT PRO-short-label [PRO:DNx] synonym: "IRF-7 (human)" EXACT [UniProtKB:Q92985] xref: UniProtKB:Q92985 xref: Reactome:R-HSA-450274 "PR:Q92985 located_in GO:0010008" xref: Reactome:R-HSA-450281 "PR:Q92985 located_in GO:0005829" intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000002049 ! interferon regulatory factor 7 relationship: has_gene_template HGNC:6122 ! IRF7 (human) [Term] id: PR:000028704 name: interferon regulatory factor 7 unmodified form (human) def: "An interferon regulatory factor 7 unmodified form in human." [PRO:CNA] comment: Category=organism-modification. synonym: "hIRF7/UnMod" EXACT PRO-short-label [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000028703 ! interferon regulatory factor 7 unmodified form