[Term]
id: PR:P56477-1
name: interferon regulatory factor 5 isoform 1 (mouse)
def: "An interferon regulatory factor 5 isoform 1 that is encoded in the genome of mouse." [PMID:18332133, PRO:CNA]
comment: Category=organism-sequence.
synonym: "MuIRF-5" EXACT []
synonym: "mIRF5/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P56477-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000027087 ! interferon regulatory factor 5 isoform 1

[Term]
id: PR:Q13568-1
name: interferon regulatory factor 5 isoform 1 (human)
def: "An interferon regulatory factor 5 isoform 1 that is encoded in the genome of human." [PMID:15805103, PRO:CNA]
comment: Category=organism-sequence.
synonym: "hIRF-5 v6" EXACT []
synonym: "hIRF5/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q13568-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027087 ! interferon regulatory factor 5 isoform 1

[Term]
id: PR:Q13568-2
name: interferon regulatory factor 5 isoform h2 (human)
def: "An interferon regulatory factor 5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13568-2." [PRO:DNx, UniProtKB:Q13568]
comment: Category=organism-sequence.
synonym: "hIRF5/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q13568-2
is_a: PR:Q13568 ! interferon regulatory factor 5 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q13568-3
name: interferon regulatory factor 5 isoform h3 (human)
def: "An interferon regulatory factor 5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13568-3." [PRO:DNx, UniProtKB:Q13568]
comment: Category=organism-sequence.
synonym: "hIRF5/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q13568-3
is_a: PR:Q13568 ! interferon regulatory factor 5 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P56477
name: interferon regulatory factor 5 (mouse)
def: "An interferon regulatory factor 5 that is encoded in the genome of mouse." [OMA:P56477, PRO:DNx]
comment: Category=organism-gene.
synonym: "Irf5" RELATED Gene-based [UniProtKB:P56477]
synonym: "mIRF5" EXACT PRO-short-label [PRO:DNx]
synonym: "IRF-5 (mouse)" EXACT [UniProtKB:P56477]
xref: UniProtKB:P56477
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000002047 ! interferon regulatory factor 5
relationship: has_gene_template MGI:1350924 ! Irf5 (mouse)

[Term]
id: PR:000002047
name: interferon regulatory factor 5
def: "An interferon regulatory factor 3-9 that is a translation product of the human IRF5 gene or a 1:1 ortholog thereof." [PRO:WCB]
comment: Category=gene.
synonym: "IRF5" EXACT PRO-short-label [PRO:DNx]
synonym: "IRF-5" EXACT []
is_a: PR:000001863 ! interferon regulatory factor 3-9

[Term]
id: PR:Q13568-6
name: interferon regulatory factor 5 isoform h6 (human)
def: "An interferon regulatory factor 5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13568-6." [PRO:DNx, UniProtKB:Q13568]
comment: Category=organism-sequence.
synonym: "hIRF5/iso:h6" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q13568-6
is_a: PR:Q13568 ! interferon regulatory factor 5 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000027535
name: interferon regulatory factor 5 isoform 1 K63-polyubiquitinated 1 (mouse)
def: "An interferon regulatory factor 5 isoform 1 K63-polyubiquitinated 1 in mouse. UniProtKB:P56477-1, Lys-410/Lys-411, PR:000044772." [PMID:18824541, PRO:CNA, TLR:AMM]
comment: Category=organism-modification. Requested by=TLR.
synonym: "mIRF5/iso:1/K63polyUbiq:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P56477-1, Lys-410/Lys-411, PR:000044772" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000027534 ! interferon regulatory factor 5 isoform 1 K63-polyubiquitinated 1
relationship: has_part PR:000044772 ! K63-polyubiquitinylated lysine

[Term]
id: PR:000027534
name: interferon regulatory factor 5 isoform 1 K63-polyubiquitinated 1
def: "An interferon regulatory factor 5 isoform 1 that has been K63-linked polyubiquitinated in response to TLR/MyD88-dependent signaling. Ubiquitinated by TRAF6. Example: UniProtKB:P56477-1, Lys-410/Lys-411, PR:000044772." [PMID:18824541, PRO:CNA]
comment: Category=modification.
synonym: "IRF5/iso:1/Ubiq:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027087 ! interferon regulatory factor 5 isoform 1
relationship: has_part PR:000044772 ! K63-polyubiquitinylated lysine

[Term]
id: PR:000027090
name: interferon regulatory factor 5 isoform 2
def: "An interferon regulatory factor 5 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:B2CC69 or a 1:1 ortholog thereof." [PMID:18332133, PRO:CNA]
comment: Category=sequence.
synonym: "IRF-5 BMv" EXACT []
synonym: "IRF5/iso:2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000002047 ! interferon regulatory factor 5

[Term]
id: PR:Q5ZJM5
name: uncharacterized protein, RCJMB04_17b14 translation product (chicken)
def: "An interferon regulatory factor 5 that is encoded in the genome of chicken." [PANTHER:PTHR11949:SF10, PRO:DAN]
comment: Category=organism-gene.
synonym: "chick-IRF5" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q5ZJM5
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000002047 ! interferon regulatory factor 5
relationship: has_gene_template CGNC:53929 ! IRF5 (chicken)

[Term]
id: PR:000027093
name: interferon regulatory factor 5 isoform 1 phosphorylated 1
def: "An interferon regulatory factor 5 isoform 1 that has been phosphorylated on Ser residues within the C-terminal region, leading to a conformational change and promoting dimerization." [PMID:18332133, PRO:CNA]
comment: Category=modification.
synonym: "IRF5/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027087 ! interferon regulatory factor 5 isoform 1
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:000027094
name: interferon regulatory factor 5 isoform 1 phosphorylated 1 (mouse)
def: "An interferon regulatory factor 5 isoform 1 phosphorylated 1 in mouse." [PMID:18332133, PRO:CNA]
comment: Category=organism-modification.
synonym: "mIRF5/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000027093 ! interferon regulatory factor 5 isoform 1 phosphorylated 1
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:000027095
name: interferon regulatory factor 5 isoform 2 phosphorylated 1
def: "An interferon regulatory factor 5 isoform 2 that has been phosphorylated on Ser residues within the C-terminal region, leading to a conformational change and promoting dimerization." [PMID:18332133, PRO:CNA]
comment: Category=modification.
synonym: "IRF5/iso:2/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027090 ! interferon regulatory factor 5 isoform 2
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:000027096
name: interferon regulatory factor 5 isoform 2 phosphorylated 1 (mouse)
def: "An interferon regulatory factor 5 isoform 2 phosphorylated 1 in mouse." [PMID:18332133, PRO:CNA]
comment: Category=organism-modification.
synonym: "mIRF5/iso:2/Phos:1" EXACT PRO-short-label [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000027095 ! interferon regulatory factor 5 isoform 2 phosphorylated 1
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:Q13568-4
name: interferon regulatory factor 5 isoform h4 (human)
def: "An interferon regulatory factor 5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13568-4." [PRO:DNx, UniProtKB:Q13568]
comment: Category=organism-sequence.
synonym: "hIRF5/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q13568-4
is_a: PR:Q13568 ! interferon regulatory factor 5 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:B2CC69
name: interferon regulatory factor 5 isoform 2 (mouse)
def: "An interferon regulatory factor 5 isoform 2 that is encoded in the genome of mouse. This isoform contains contains an internal deletion of most of exons 4 to 6 in comparison to isoform 1." [PMID:18332133, PRO:CNA]
comment: Category=organism-sequence.
synonym: "MuIRF-5 BMv" EXACT []
synonym: "mIRF5/iso:2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:B2CC69
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000027090 ! interferon regulatory factor 5 isoform 2

[Term]
id: PR:000027087
name: interferon regulatory factor 5 isoform 1
def: "An interferon regulatory factor 5 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P56477-1 or a 1:1 ortholog thereof." [PMID:18332133, PRO:CNA]
comment: Category=sequence.
synonym: "IRF5/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000002047 ! interferon regulatory factor 5

[Term]
id: PR:Q13568-5
name: interferon regulatory factor 5 isoform h5 (human)
def: "An interferon regulatory factor 5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13568-5." [PRO:DNx, UniProtKB:Q13568]
comment: Category=organism-sequence.
synonym: "hIRF5/iso:h5" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q13568-5
is_a: PR:Q13568 ! interferon regulatory factor 5 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q13568
name: interferon regulatory factor 5 (human)
def: "An interferon regulatory factor 5 that is encoded in the genome of human." [PRO:WCB, UniProtKB:Q13568]
comment: Category=organism-gene.
synonym: "IRF5" RELATED Gene-based [UniProtKB:Q13568]
synonym: "hIRF5" EXACT PRO-short-label [PRO:DNx]
synonym: "IRF-5 (human)" EXACT [UniProtKB:Q13568]
xref: Reactome:R-HSA-1015676 "PR:Q13568 located_in GO:0005829"
xref: UniProtKB:Q13568
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002047 ! interferon regulatory factor 5
relationship: has_gene_template HGNC:6120 ! IRF5 (human)