[Term] id: PR:000001969 name: urokinase plasminogen activator surface receptor def: "A protein that is a translation product of the human PLAUR gene or a 1:1 ortholog thereof." [PRO:WCB] comment: Category=gene. Requested by=CL. synonym: "MO3" RELATED Gene-based [] synonym: "CD87" EXACT [] synonym: "UPAR" RELATED Gene-based [] synonym: "uPAR" EXACT [] synonym: "PLAUR" EXACT PRO-short-label [PRO:DNx] synonym: "U-PAR" EXACT [] synonym: "monocyte activation antigen Mo3" EXACT [] xref: PIRSF:PIRSF002022 is_a: PR:000000001 ! protein [Term] id: PR:Q03405 name: urokinase plasminogen activator surface receptor (human) def: "A urokinase plasminogen activator surface receptor that is encoded in the genome of human." [PRO:WCB, UniProtKB:Q03405] comment: Category=organism-gene. synonym: "MO3" RELATED Gene-based [UniProtKB:Q03405] synonym: "UPAR" RELATED Gene-based [UniProtKB:Q03405] synonym: "PLAUR" RELATED Gene-based [UniProtKB:Q03405] synonym: "hPLAUR" EXACT PRO-short-label [PRO:DNx] synonym: "CD87 (human)" EXACT [UniProtKB:Q03405] synonym: "U-PAR (human)" EXACT [UniProtKB:Q03405] synonym: "monocyte activation antigen Mo3 (human)" EXACT [UniProtKB:Q03405] xref: UniProtKB:Q03405 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000001969 ! urokinase plasminogen activator surface receptor relationship: has_gene_template HGNC:9053 ! PLAUR (human) [Term] id: PR:000048798 name: urokinase plasminogen activator surface receptor, signal peptide removed form (human) def: "A urokinase plasminogen activator surface receptor (human) that has had the signal peptide removed. UniProtKB:Q03405, 23-335." [PRO:DNx, Reactome:R-HSA-162866] comment: Category=organism-modification. synonym: "hPLAUR/SigPep-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q03405, 23-335" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-162866 "PR:000048798 located_in GO:0005789" intersection_of: PR:Q03405 ! urokinase plasminogen activator surface receptor (human) intersection_of: lacks_part SO:0000418 ! signal_peptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000050322 name: urokinase plasminogen activator surface receptor membrane-bound form (human) def: "A urokinase plasminogen activator surface receptor (human) that has had the signal peptide and propeptide removed, with subsequent attachment to the cell membrane via GPI-anchor. UniProtKB:Q03405, 23-305, Gly-305, MOD:00170." [PMID:19893210, PRO:DAN] comment: Category=organism-modification. synonym: "hPLAUR/membrane" EXACT PRO-short-label [PRO:DAN] synonym: "UniProtKB:Q03405, 23-305, Gly-305, MOD:00170" EXACT PRO-proteoform-std [PRO:DAN] synonym: "mature urokinase plasminogen activator receptor (human)" EXACT [PRO:DAN] intersection_of: has_part MOD:00170 ! N-glycyl-glycosylphosphatidylinositolethanolamine intersection_of: PR:Q03405 ! urokinase plasminogen activator surface receptor (human) intersection_of: lacks_part SO:0000418 ! signal_peptide intersection_of: lacks_part SO:0001062 ! propeptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000050323 name: soluble urokinase plasminogen activator surface receptor (human) def: "A urokinase plasminogen activator surface receptor (human) that has had the signal peptide and propeptide removed, subsequently attached to the cell membrane via GPI anchor, and then detached." [PMID:1325906, PMID:19893210, PRO:DAN] comment: Category=organism-modification. synonym: "suPAR (human)" EXACT [PRO:DAN] synonym: "hPLAUR/soluble" EXACT PRO-short-label [PRO:DAN] synonym: "soluble urokinase plasminogen activator receptor (human)" EXACT [PRO:DAN] intersection_of: lacks_part MOD:00170 ! N-glycyl-glycosylphosphatidylinositolethanolamine intersection_of: PR:Q03405 ! urokinase plasminogen activator surface receptor (human) intersection_of: lacks_part SO:0000418 ! signal_peptide intersection_of: lacks_part SO:0001062 ! propeptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q03405-3 name: urokinase plasminogen activator surface receptor isoform h3 (human) def: "A urokinase plasminogen activator surface receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q03405-3." [PRO:DNx, UniProtKB:Q03405] comment: Category=organism-sequence. synonym: "hPLAUR/iso:h3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q03405-3 is_a: PR:Q03405 ! urokinase plasminogen activator surface receptor (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q03405-2 name: urokinase plasminogen activator surface receptor isoform h2 (human) def: "A urokinase plasminogen activator surface receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q03405-2." [PRO:DNx, UniProtKB:Q03405] comment: Category=organism-sequence. synonym: "hPLAUR/iso:h2" EXACT PRO-short-label [PRO:DNx] synonym: "uPAR7b (human)" EXACT [PRO:DAN, PMID:25797271] synonym: "urokinase plasminogen activator surface receptor isoform uPAR2 (human)" EXACT [UniProtKB:Q03405] synonym: "urokinase plasminogen activator surface receptor isoform Secreted (human)" EXACT [UniProtKB:Q03405] xref: UniProtKB:Q03405-2 is_a: PR:Q03405 ! urokinase plasminogen activator surface receptor (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q03405-1 name: urokinase plasminogen activator surface receptor isoform h1 (human) def: "A urokinase plasminogen activator surface receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q03405-1." [PRO:DNx, UniProtKB:Q03405] comment: Category=organism-sequence. synonym: "hPLAUR/iso:h1" EXACT PRO-short-label [PRO:DNx] synonym: "urokinase plasminogen activator surface receptor isoform uPAR1 (human)" EXACT [UniProtKB:Q03405] synonym: "urokinase plasminogen activator surface receptor isoform GPI-anchored (human)" EXACT [UniProtKB:Q03405] xref: UniProtKB:Q03405-1 is_a: PR:Q03405 ! urokinase plasminogen activator surface receptor (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens