[Term]
id: PR:000001940
name: tissue factor
def: "A protein that is a translation product of the human F3 gene or a 1:1 ortholog thereof." [PRO:WCB]
comment: Category=gene.
synonym: "F3" EXACT PRO-short-label [PRO:DNx]
synonym: "TF" RELATED []
synonym: "Cf3" RELATED Gene-based []
synonym: "Cf-3" RELATED Gene-based []
synonym: "CD142" EXACT []
synonym: "thromboplastin" EXACT []
synonym: "coagulation factor III" EXACT []
xref: PIRSF:PIRSF002498
is_a: PR:000000001 ! protein

[Term]
id: PR:P13726-2
name: tissue factor isoform h2 (human)
def: "A tissue factor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P13726-2." [PRO:DNx, UniProtKB:P13726]
comment: Category=organism-sequence.
synonym: "hF3/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "tissue factor isoform asHTF (human)" EXACT [UniProtKB:P13726]
xref: UniProtKB:P13726-2
is_a: PR:P13726 ! tissue factor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P13726-1
name: tissue factor isoform h1 (human)
def: "A tissue factor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P13726-1." [PRO:DNx, UniProtKB:P13726]
comment: Category=organism-sequence.
synonym: "hF3/iso:h1" EXACT PRO-short-label [PRO:DNx]
synonym: "tissue factor isoform flTF (human)" EXACT [UniProtKB:P13726]
xref: UniProtKB:P13726-1
is_a: PR:P13726 ! tissue factor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P13726
name: tissue factor (human)
def: "A tissue factor that is encoded in the genome of human." [PRO:WCB, UniProtKB:P13726]
comment: Category=organism-gene.
synonym: "F3" RELATED Gene-based [UniProtKB:P13726]
synonym: "hF3" EXACT PRO-short-label [PRO:DNx]
synonym: "TF (human)" EXACT [UniProtKB:P13726]
synonym: "CD142 (human)" EXACT [UniProtKB:P13726]
synonym: "thromboplastin (human)" EXACT [UniProtKB:P13726]
synonym: "coagulation factor III (human)" EXACT [UniProtKB:P13726]
xref: UniProtKB:P13726
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001940 ! tissue factor
relationship: has_gene_template HGNC:3541 ! F3 (human)

[Term]
id: PR:000047353
name: tissue factor, signal peptide removed palmitoylated 1 (human)
def: "A tissue factor (human) that has had the signal peptide removed and has been post-translationally modified to include palmitoylated residue at position 277 of the amino acid sequence represented by UniProtKB:P13726. UniProtKB:P13726, 33-295, Cys-277, MOD:00115." [PRO:DNx, Reactome:R-HSA-140704]
comment: Category=organism-modification.
synonym: "hF3/SigPep-/Palm:1" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000033638, Cys-277, MOD:00115" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P13726, 33-295, Cys-277, MOD:00115" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-140704 "PR:000047353 located_in GO:0005886"
is_a: PR:P13726 ! tissue factor (human)
relationship: has_part MOD:00115 ! S-palmitoyl-L-cysteine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part SO:0000418 ! signal_peptide

[Term]
id: PR:000047352
name: tissue factor, signal peptide removed form (human)
def: "A tissue factor (human) that has had the signal peptide removed. UniProtKB:P13726, 33-295." [PRO:DNx, Reactome:R-HSA-140762]
comment: Category=organism-modification.
synonym: "hF3/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000033638" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P13726, 33-295" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-140762 "PR:000047352 located_in GO:0005886"
intersection_of: PR:P13726 ! tissue factor (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens