[Term]
id: PR:000035703
name: CD14 molecule isoform 1 cleaved 2 soluble form (human)
def: "A CD14 molecule isoform 1 cleaved 2 soluble form in human. UniProtKB:P08571-1, 20-345." [PRO:DNx, UniProtKB:P08571]
comment: Category=organism-modification.
synonym: "PRO_0000020885" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hCD14/iso:1/Clv:2/soluble" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P08571-1, 20-345" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "Secreted form of CD14 (human)" EXACT [Reactome:R-HSA-166025]
xref: Reactome:R-HSA-166025 "PR:000035703 located_in GO:0005576"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002147 ! CD14 molecule isoform 1 cleaved 2 soluble form

[Term]
id: PR:000035702
name: CD14 molecule isoform 1 cleaved 2 GPI-anchored form (human)
def: "A CD14 molecule isoform 1 cleaved 2 GPI-anchored form in human. UniProtKB:P08571-1, 20-345, Asn-345, MOD:00167." [Reactome:R-HSA-166033, Reactome:R-HSA-2201284]
comment: Category=organism-modification.
synonym: "GPI-N345-CD14 (human)" EXACT [Reactome:R-HSA-166033, Reactome:R-HSA-2201284]
synonym: "hCD14/iso:1/Clv:2/anchored" EXACT PRO-short-label [PRO:DAN]
synonym: "GPI-anchored form of CD14 (human)" EXACT [Reactome:R-HSA-166033, Reactome:R-HSA-2201284]
synonym: "PRO_0000020885, Asn-345, MOD:00167" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P08571-1, 20-345, Asn-345, MOD:00167" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-166033 "PR:000035702 located_in GO:0005886"
xref: Reactome:R-HSA-2201284 "PR:000035702 located_in GO:0010008"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002149 ! CD14 molecule isoform 1 cleaved 2 GPI-anchored form
relationship: has_part MOD:00167 ! N-asparaginyl-glycosylphosphatidylinositolethanolamine

[Term]
id: PR:000054476
name: monocyte differentiation antigen CD14 N-glycosylated 1 (human)
def: "A monocyte differentiation antigen CD14 (human) that has been N-glycosylated at the residue equivalent to Asn-151 of the amino acid sequence represented by UniProtKB:P08571-1, in which the glycan composition is represented by GlyTouCan:G59626AS. Example: UniProtKB:P08571-1, Asn-151, MOD:00160~GNO:G59626AS." [GlyGen:P08571-1, PMID:29671580, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hCD14/NGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P08571-1, Asn-151, MOD:00160~GNO:G59626AS" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P08571 ! monocyte differentiation antigen CD14 (human)
relationship: has_part GNO:G59626AS ! G59626AS
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P08571-1
name: monocyte differentiation antigen CD14 isoform 1 (human)
def: "A CD14 molecule isoform 1 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hCD14/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P08571-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002144 ! CD14 molecule isoform 1

[Term]
id: PR:000001889
name: CD14 molecule
def: "A protein that is a translation product of the human CD14 gene or a 1:1 ortholog thereof." [PRO:WCB]
comment: Category=gene. Requested by=CL.
synonym: "CD14" EXACT PRO-short-label [PRO:DNx]
synonym: "monocyte differentiation antigen CD14" EXACT []
synonym: "myeloid cell-specific leucine-rich glycoprotein" EXACT []
xref: PIRSF:PIRSF002017
is_a: PR:000000001 ! protein

[Term]
id: PR:000050392
name: presepsin (human)
def: "A CD14 molecule isoform 1, signal peptide removed form that has been cleaved by plasma proteases to yield a soluble 13kD N-terminal fragment in human." [PMID:16258819, PMID:21740312, PMID:25215141, PRO:DAN]
comment: Category=organism-modification. Note: The cleavage position indicated in [PMID:21740312] is based on a synthetic construct; the true point of cleavage is unknown. It is believed that presepsin is derived from a membrane-bound precursor as opposed to a secreted form [PMID:16258819].
synonym: "hPSEP" EXACT PRO-short-label [PRO:DAN]
synonym: "PSEP (human)" EXACT [PRO:DAN]
synonym: "P-SEP (human)" EXACT [PRO:DAN]
synonym: "sCD14-ST (human)" EXACT [PRO:DAN]
synonym: "soluble CD14 subtype (human)" EXACT [PRO:DAN]
synonym: "soluble cluster of differentiation 14 subtype (human)" EXACT [PRO:DAN]
is_a: PR:000025460 ! CD14 molecule isoform 1, signal peptide removed form
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000054480
name: monocyte differentiation antigen CD14 O-glycosylated 4 (human)
def: "A monocyte differentiation antigen CD14 (human) that has been O-glycosylated at the residue equivalent to Thr-336 of the amino acid sequence represented by UniProtKB:P08571-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P08571-1, Thr-336, MOD:00005~GNO:G43417UB." [GlyGen:P08571-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hCD14/OGlyco:4" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P08571-1, Thr-336, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P08571 ! monocyte differentiation antigen CD14 (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P08571
name: monocyte differentiation antigen CD14 (human)
def: "A CD14 molecule that is encoded in the genome of human." [PRO:WCB, UniProtKB:P08571]
comment: Category=organism-gene.
synonym: "CD14" RELATED Gene-based [UniProtKB:P08571]
synonym: "hCD14" EXACT PRO-short-label [PRO:DNx]
synonym: "myeloid cell-specific leucine-rich glycoprotein (human)" EXACT [UniProtKB:P08571]
xref: UniProtKB:P08571
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001889 ! CD14 molecule
relationship: has_gene_template HGNC:1628 ! CD14 (human)

[Term]
id: PR:000036945
name: CD14 molecule isoform 1 cleaved and soluble form (human)
def: "A CD14 molecule isoform 1 cleaved and soluble form in human." [PRO:DAN]
comment: Category=organism-modification.
synonym: "hCD14/iso:1/ClvPrd/soluble" EXACT PRO-short-label [PRO:DAN]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000036849 ! CD14 molecule isoform 1 cleaved and soluble form
union_of: PR:000035703 ! CD14 molecule isoform 1 cleaved 2 soluble form (human)
union_of: PR:000036615 ! CD14 molecule isoform 1 cleaved 1 soluble form (human)

[Term]
id: PR:000037480
name: CD14 molecule isoform 1 cleaved 2 (human)
def: "A CD14 molecule isoform 1 cleaved 2 in human. This represents both the GPI-anchored and soluble forms." [PRO:CNA, PRO:DAN]
comment: Category=organism-modification.
synonym: "hCD14/iso:1/Clv:2" EXACT PRO-short-label [PRO:DAN]
synonym: "CD14 molecule (human)" RELATED [PRO:CNA]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000036848 ! CD14 molecule isoform 1 cleaved 2
union_of: PR:000035702 ! CD14 molecule isoform 1 cleaved 2 GPI-anchored form (human)
union_of: PR:000035703 ! CD14 molecule isoform 1 cleaved 2 soluble form (human)

[Term]
id: PR:000054477
name: monocyte differentiation antigen CD14 O-glycosylated 1 (human)
def: "A monocyte differentiation antigen CD14 (human) that has been O-glycosylated at the residue equivalent to Ser-362 of the amino acid sequence represented by UniProtKB:P08571-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P08571-1, Ser-362, MOD:00002~GNO:G43417UB." [GlyGen:P08571-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hCD14/OGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P08571-1, Ser-362, MOD:00002~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P08571 ! monocyte differentiation antigen CD14 (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00002 ! O-glycosyl-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000054478
name: monocyte differentiation antigen CD14 O-glycosylated 2 (human)
def: "A monocyte differentiation antigen CD14 (human) that has been O-glycosylated at the residue equivalent to Thr-336 of the amino acid sequence represented by UniProtKB:P08571-1, in which the glycan composition is represented by GlyTouCan:G27391WQ. Example: UniProtKB:P08571-1, Thr-336, MOD:00005~GNO:G27391WQ." [GlyGen:P08571-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hCD14/OGlyco:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P08571-1, Thr-336, MOD:00005~GNO:G27391WQ" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P08571 ! monocyte differentiation antigen CD14 (human)
relationship: has_part GNO:G27391WQ ! G27391WQ
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000054479
name: monocyte differentiation antigen CD14 O-glycosylated 3 (human)
def: "A monocyte differentiation antigen CD14 (human) that has been O-glycosylated at the residue equivalent to Thr-336 of the amino acid sequence represented by UniProtKB:P08571-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P08571-1, Thr-336, MOD:00005~GNO:G29068FM." [GlyGen:P08571-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hCD14/OGlyco:3" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P08571-1, Thr-336, MOD:00005~GNO:G29068FM" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P08571 ! monocyte differentiation antigen CD14 (human)
relationship: has_part GNO:G29068FM ! G29068FM
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000054481
name: monocyte differentiation antigen CD14 O-glycosylated 5 (human)
def: "A monocyte differentiation antigen CD14 (human) that has been O-glycosylated at the residue equivalent to Thr-364 of the amino acid sequence represented by UniProtKB:P08571-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P08571-1, Thr-364, MOD:00005~GNO:G43417UB." [GlyGen:P08571-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hCD14/OGlyco:5" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P08571-1, Thr-364, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P08571 ! monocyte differentiation antigen CD14 (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000036615
name: CD14 molecule isoform 1 cleaved 1 soluble form (human)
def: "A CD14 molecule isoform 1 cleaved 1 soluble form in human. UniProtKB:P08571-1, 20-367." [PMID:7519994, PRO:CNA]
comment: Category=organism-modification.
synonym: "PRO_0000020884" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hCD14/iso:1/Clv:1/soluble" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P08571-1, 20-367" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000002146 ! CD14 molecule isoform 1 cleaved 1 soluble form