[Term]
id: PR:000001869
name: interleukin-7 receptor subunit alpha
def: "A protein that is a translation product of the human IL7R gene or a 1:1 ortholog thereof." [PRO:WCB]
comment: Category=gene. Requested by=CL.
synonym: "IL7R" EXACT PRO-short-label [PRO:DNx]
synonym: "CD127" EXACT []
synonym: "CDw127" EXACT []
synonym: "IL-7RA" EXACT []
synonym: "IL-7R-alpha" EXACT []
synonym: "IL-7R subunit alpha" EXACT []
synonym: "IL-7 receptor subunit alpha" EXACT []
xref: IUPHARobj:1698
xref: PIRSF:PIRSF001960
is_a: PR:000000001 ! protein

[Term]
id: PR:P16871
name: interleukin-7 receptor subunit alpha (human)
def: "An interleukin-7 receptor subunit alpha that is encoded in the genome of human." [PRO:WCB, UniProtKB:P16871]
comment: Category=organism-gene.
synonym: "IL7R" RELATED Gene-based [UniProtKB:P16871]
synonym: "hIL7R" EXACT PRO-short-label [PRO:DNx]
synonym: "CD127 (human)" EXACT [UniProtKB:P16871]
synonym: "CDw127 (human)" EXACT [UniProtKB:P16871]
synonym: "IL-7RA (human)" EXACT [UniProtKB:P16871]
synonym: "IL-7R-alpha (human)" EXACT [UniProtKB:P16871]
synonym: "IL-7R subunit alpha (human)" EXACT [UniProtKB:P16871]
synonym: "IL-7 receptor subunit alpha (human)" EXACT [UniProtKB:P16871]
xref: UniProtKB:P16871
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001869 ! interleukin-7 receptor subunit alpha
relationship: has_gene_template HGNC:6024 ! IL7R (human)

[Term]
id: PR:000048033
name: interleukin-7 receptor subunit alpha, signal peptide removed phosphorylated 1 (human)
def: "An interleukin-7 receptor subunit alpha (human) that has had the signal peptide removed and has been post-translationally modified to include phosphotyrosine at position 449 of the amino acid sequence represented by UniProtKB:P16871. UniProtKB:P16871, 21-459, Tyr-449, MOD:00048." [PRO:DNx, Reactome:R-HSA-1295531]
comment: Category=organism-modification.
synonym: "hIL7R/SigPep-/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000010909, Tyr-449, MOD:00048" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P16871, 21-459, Tyr-449, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-1295531 "PR:000048033 located_in GO:0005886"
is_a: PR:P16871 ! interleukin-7 receptor subunit alpha (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part SO:0000418 ! signal_peptide

[Term]
id: PR:000048032
name: interleukin-7 receptor subunit alpha, signal peptide removed form (human)
def: "An interleukin-7 receptor subunit alpha (human) that has had the signal peptide removed. UniProtKB:P16871, 21-459." [PRO:DNx, Reactome:R-HSA-449945]
comment: Category=organism-modification.
synonym: "hIL7R/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000010909" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P16871, 21-459" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-449945 "PR:000048032 located_in GO:0005886"
xref: Reactome:R-HSA-9028500 "PR:000048032 located_in GO:0030669"
intersection_of: PR:P16871 ! interleukin-7 receptor subunit alpha (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P16871-4
name: interleukin-7 receptor subunit alpha isoform h2 (human)
def: "An interleukin-7 receptor subunit alpha (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16871-4." [PRO:DNx, UniProtKB:P16871]
comment: Category=organism-sequence.
synonym: "hIL7R/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "interleukin-7 receptor subunit alpha isoform Secreted (human)" BROAD [UniProtKB:P16871]
xref: UniProtKB:P16871-4
is_a: PR:P16871 ! interleukin-7 receptor subunit alpha (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P16871-3
name: interleukin-7 receptor subunit alpha isoform h4 (human)
def: "An interleukin-7 receptor subunit alpha (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16871-3." [PRO:DNx, UniProtKB:P16871]
comment: Category=organism-sequence.
synonym: "hIL7R/iso:h4" EXACT PRO-short-label [PRO:DNx]
synonym: "interleukin-7 receptor subunit alpha isoform H6 (human)" EXACT [UniProtKB:P16871]
synonym: "interleukin-7 receptor subunit alpha isoform Secreted (human)" BROAD [UniProtKB:P16871]
xref: UniProtKB:P16871-3
is_a: PR:P16871 ! interleukin-7 receptor subunit alpha (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P16871-2
name: interleukin-7 receptor subunit alpha isoform h3 (human)
def: "An interleukin-7 receptor subunit alpha (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16871-2." [PRO:DNx, UniProtKB:P16871]
comment: Category=organism-sequence.
synonym: "hIL7R/iso:h3" EXACT PRO-short-label [PRO:DNx]
synonym: "interleukin-7 receptor subunit alpha isoform H1 (human)" EXACT [UniProtKB:P16871]
xref: UniProtKB:P16871-2
is_a: PR:P16871 ! interleukin-7 receptor subunit alpha (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P16871-1
name: interleukin-7 receptor subunit alpha isoform h1 (human)
def: "An interleukin-7 receptor subunit alpha (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16871-1." [PRO:DNx, UniProtKB:P16871]
comment: Category=organism-sequence.
synonym: "hIL7R/iso:h1" EXACT PRO-short-label [PRO:DNx]
synonym: "interleukin-7 receptor subunit alpha isoform H20 (human)" EXACT [UniProtKB:P16871]
xref: UniProtKB:P16871-1
is_a: PR:P16871 ! interleukin-7 receptor subunit alpha (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens