[Term]
id: PR:000001823
name: MHC class II transactivator
def: "A protein that is a translation product of the human CIITA gene or a 1:1 ortholog thereof." [PRO:WCB]
comment: Category=gene.
synonym: "C2ta" RELATED Gene-based []
synonym: "CIITA" EXACT PRO-short-label [PRO:DNx]
synonym: "MHC2TA" RELATED Gene-based []
xref: IUPHARobj:1767
is_a: PR:000000001 ! protein

[Term]
id: PR:P33076-4
name: MHC class II transactivator isoform h4 (human)
def: "An MHC class II transactivator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P33076-4." [PRO:DNx, UniProtKB:P33076]
comment: Category=organism-sequence.
synonym: "hCIITA/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P33076-4
is_a: PR:P33076 ! MHC class II transactivator (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P33076
name: MHC class II transactivator (human)
def: "An MHC class II transactivator that is encoded in the genome of human." [PRO:WCB, UniProtKB:P33076]
comment: Category=organism-gene.
synonym: "CIITA" RELATED Gene-based [UniProtKB:P33076]
synonym: "MHC2TA" RELATED Gene-based [UniProtKB:P33076]
synonym: "hCIITA" EXACT PRO-short-label [PRO:DNx]
xref: Reactome:R-HSA-1031702 "PR:P33076 located_in GO:0005654"
xref: UniProtKB:P33076
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001823 ! MHC class II transactivator
relationship: has_gene_template HGNC:7067 ! CIITA (human)

[Term]
id: PR:P33076-3
name: MHC class II transactivator isoform h3 (human)
def: "An MHC class II transactivator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P33076-3." [PRO:DNx, UniProtKB:P33076]
comment: Category=organism-sequence.
synonym: "hCIITA/iso:h3" EXACT PRO-short-label [PRO:DNx]
synonym: "MHC class II transactivator isoform hCIITA' (human)" EXACT [UniProtKB:P33076]
xref: UniProtKB:P33076-3
is_a: PR:P33076 ! MHC class II transactivator (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P33076-2
name: MHC class II transactivator isoform h2 (human)
def: "An MHC class II transactivator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P33076-2." [PRO:DNx, UniProtKB:P33076]
comment: Category=organism-sequence.
synonym: "hCIITA/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P33076-2
is_a: PR:P33076 ! MHC class II transactivator (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000028745
name: MHC class II transactivator isoform 1 acetylated 1 (human)
def: "An MHC class II transactivator isoform 1 acetylated 1 in human. UniProtKB:P33076-1, Lys-141/Lys-144, MOD:00064." [PMID:11046145, PRO:PD]
comment: Category=organism-modification. Acetylase=("CREBBP"; PR:Q92793). Acetylase=("KAT2B"; PR:000012332).
synonym: "hCIITA/iso:1/Ac:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P33076-1, Lys-141/Lys-144, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000028744 ! MHC class II transactivator isoform 1 acetylated 1
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine

[Term]
id: PR:P33076-1
name: MHC class II transactivator isoform 1 (human)
def: "An MHC class II transactivator isoform 1 that is encoded in the genome of human." [PRO:PD]
comment: Category=organism-sequence.
synonym: "hCIITA/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P33076-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000028742 ! MHC class II transactivator isoform 1