[Term]
id: PR:000001785
name: prominin
def: "A protein with core architecture consisting of one Prominin (Pfam:PF05478) domain. The prominins are an emerging family of proteins that, among the multispan membrane proteins, display a novel topology. Mouse and human prominin and prominin-like 1 are predicted to contain five membrane spanning domains, with an N-terminal domain exposed to the extracellular space followed by four, alternating small cytoplasmic and large extracellular, loops and a cytoplasmic C-terminal domain." [InterPro:IPR008795, PMID:11467842]
comment: Category=family.
xref: PIRSF:PIRSF017831
xref: PANTHER:PTHR22730
is_a: PR:000000001 ! protein