[Term]
id: PR:O43187
name: interleukin-1 receptor-associated kinase-like 2 (human)
def: "An interleukin-1 receptor-associated kinase-like 2 that is encoded in the genome of human." [PRO:CNA, UniProtKB:O43187]
comment: Category=organism-gene.
synonym: "IRAK2" RELATED Gene-based [UniProtKB:O43187]
synonym: "hIRAK2" EXACT PRO-short-label [PRO:DNx]
synonym: "IRAK-2 (human)" EXACT [UniProtKB:O43187]
xref: Reactome:R-HSA-772534 "PR:O43187 located_in GO:0005829"
xref: Reactome:R-HSA-937014 "PR:O43187 located_in GO:0005886"
xref: Reactome:R-HSA-975116 "PR:O43187 located_in GO:0010008"
xref: DTO:03100191
xref: UniProtKB:O43187
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001783 ! interleukin-1 receptor-associated kinase-like 2
relationship: has_gene_template HGNC:6113 ! IRAK2 (human)

[Term]
id: PR:000048045
name: interleukin-1 receptor-associated kinase-like 2 phosphorylated form (human)
def: "An interleukin-1 receptor-associated kinase-like 2 (human) that includes at least one phosphorylated residue. UniProtKB:O43187, MOD:00696." [PRO:DNx, Reactome:R-HSA-446636, Reactome:R-HSA-936949, Reactome:R-HSA-975187]
comment: Category=organism-modification.
synonym: "hIRAK2/PhosRes+" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O43187, MOD:00696" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-936949 "PR:000048045 located_in GO:0005886"
xref: Reactome:R-HSA-975187 "PR:000048045 located_in GO:0010008"
xref: Reactome:R-HSA-446636 "PR:000048045 located_in GO:0005829"
intersection_of: has_part MOD:00696 ! phosphorylated residue
intersection_of: PR:O43187 ! interleukin-1 receptor-associated kinase-like 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000001783
name: interleukin-1 receptor-associated kinase-like 2
def: "An interleukin-1 receptor-associated kinase IRAK1/3 that is a translation product of the human IRAK2 gene or a 1:1 ortholog thereof. This protein class is inactive as a kinase due to a change of an Asn instead of an Asp redisue in a catalytic site." [PMID:9374458, PRO:CNA]
comment: Category=gene.
synonym: "IRAK2" EXACT PRO-short-label [PRO:DNx]
synonym: "IRAK-2" EXACT []
synonym: "mu-IRAK-2" EXACT []
xref: IUPHARobj:2043
is_a: PR:000001781 ! interleukin-1 receptor-associated kinase IRAK1/3